ChemicalBook > CAS DataBase List > 7-bromo-4H-chromen-4-one

7-bromo-4H-chromen-4-one

Product Name
7-bromo-4H-chromen-4-one
CAS No.
168759-60-2
Chemical Name
7-bromo-4H-chromen-4-one
Synonyms
7-Bromochromone;7-Bromochromen-4-one;7-bromo-4H-chromen-4-one;7-Bromo-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 7-broMo-;1,2-Ethanediamine,N1-(5-methylpropyl)-
CBNumber
CB92513981
Molecular Formula
C9H5BrO2
Formula Weight
225.04
MOL File
168759-60-2.mol
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7-bromo-4H-chromen-4-one Property

Melting point:
154-159°C
Boiling point:
306.0±42.0 °C(Predicted)
Density 
1.688±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
732818
Product name
7-Bromochromone
Packaging
250mg
Price
$60.3
Updated
2023/06/20
TRC
Product number
B686168
Product name
7-Bromo-4H-chromen-4-one
Packaging
500mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB141433
Product name
7-Bromo-4H-chromen-4-one
Packaging
500mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB141433
Product name
7-Bromo-4H-chromen-4-one
Packaging
100mg
Price
$53
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB141433
Product name
7-Bromo-4H-chromen-4-one
Packaging
250mg
Price
$105
Updated
2021/12/16
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7-bromo-4H-chromen-4-one Chemical Properties,Usage,Production

Synthesis

945724-02-7

168759-60-2

General procedure for the synthesis of 7-bromo-4H-chromen-4-one from (E)-1-(4-bromo-2-hydroxyphenyl)-3-(dimethylamino)prop-2-en-1-one: Concentrated hydrochloric acid (30 mL) was slowly added to a (E)-1-(4-bromo-2-hydroxyphenyl)-3-(dimethylamino)prop-2-en-1-one (10.4 g, 38.5 mmol) in a solution of dichloromethane (250 mL). The reaction mixture was heated to reflux for 30 minutes and then cooled to room temperature. The aqueous phase was extracted with dichloromethane (20 mL). The organic phases were combined, washed with saturated sodium bicarbonate solution (50 mL), dried over anhydrous sodium sulfate, and filtered. The solvent was removed by concentration under reduced pressure to give 7-bromo-4H-chromen-4-one (8.7 g, 38.5 mmol, 100% yield).

References

[1] Patent: WO2012/68234, 2012, A2. Location in patent: Page/Page column 629; 630
[2] Patent: WO2007/88450, 2007, A2. Location in patent: Page/Page column 22
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 22, p. 10228 - 10243
[4] Patent: US2009/202478, 2009, A1

7-bromo-4H-chromen-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-bromo-4H-chromen-4-one Suppliers

Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai potentpharm CO.,Ltd
Tel
13524892556
Fax
(86) 21 51969655, QQ: 263541193
Email
sales-cn@potentpharm.com
Country
China
ProdList
1011
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
Nantong Bosu Pharmaceutical Technology Co., Ltd.
Tel
0513-0513-51005092 13390947892
Fax
0513-51005092
Email
tashiyxy@163.com
Country
China
ProdList
839
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Chengdu J&B Technology Co., Ltd.
Tel
028-61186694 15608078506
Fax
028-61186694
Email
609128801@qq.com
Country
China
ProdList
837
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Pingguo Pharmaceutical Co., Ltd.
Tel
021-20432229
Fax
QQ2412110556
Email
2412110556@qq.com
Country
China
ProdList
6017
Advantage
55
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View Lastest Price from 7-bromo-4H-chromen-4-one manufacturers

R&D Scientific Inc.
Product
7-Bromochromone 168759-60-2
Price
US $520.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-23

168759-60-2, 7-bromo-4H-chromen-4-oneRelated Search:


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  • 4H-1-Benzopyran-4-one, 7-broMo-
  • 7-Bromochromone
  • 7-Bromochromen-4-one
  • 1,2-Ethanediamine,N1-(5-methylpropyl)-
  • 7-Bromo-4H-1-benzopyran-4-one
  • 168759-60-2