7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Application- Product Name
- 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- CAS No.
- 882521-63-3
- Chemical Name
- 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Synonyms
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amin;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;2-AMino-7-broMo-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 7-bromo-;7-Bromo-1,2,4 Triazolo [1,5-A] Pyridine-2-amine;7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;7-bromo-[1,2,4triazole combined[1,5-A]pyridine-2-amine;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine ISO 9001：2015 REACH
- CBNumber
- CB81560271
- Molecular Formula
- C6H5BrN4
- Formula Weight
- 213.03
- MOL File
- 882521-63-3.mol
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Property
- Density
- 2.09±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 4.30±0.30(Predicted)
- form
- solid
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C6H5BrN4/c7-4-1-2-11-5(3-4)9-6(8)10-11/h1-3H,(H2,8,10)
- InChIKey
- DAYYXZOMYRSLBX-UHFFFAOYSA-N
- SMILES
- C12=NC(N)=NN1C=CC(Br)=C2
Safety
- WGK Germany
- 3
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00258
- Product name
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $330
- Updated
- 2025/07/31
- Product number
- B614675
- Product name
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B614675
- Product name
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 500mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 3H30-9-0W
- Product name
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 1g
- Price
- $247
- Updated
- 2021/12/16
- Product number
- 115574
- Product name
- 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $322
- Updated
- 2021/12/16
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Chemical Properties,Usage,Production
Application
7-Bromo-[1,2,4]triazolo[1,5-A]pyridine-2-amine is an organic intermediate that can be prepared by first preparing 1-ethoxycarbonyl-3-(4-bromo-pyridin-2-yl)-thiourea from 4-bromopyridine-2-amine and 4-bromopyridine-2-amine, and then reacting it with hydroxylamine hydrochloride to obtain 7-bromo-[1,2,4]triazolo[1,5-a]pyridine-2-amine.
Synthesis
882521-62-2
882521-63-3
1-Ethoxycarbonyl-3-(4-bromopyridin-2-yl)thiourea (17.5 g, 57.5 mmol) was mixed with hydroxylamine hydrochloride (20.0 g, 288 mmol) and N-ethyl diisopropylamine (30.1 ml, 173 mmol) in ethanol (367 ml). After stirring for a few minutes at room temperature, the reaction mixture was heated to reflux for 24 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. Water (100 ml) was added to the residue and stirred for 10 min to form a suspension. The solid product was collected by filtration, washed with water and dried to give 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine (10.71 g, 87.4% yield) as a light yellow solid. Melting point: 190-192°C. Mass spectrum (MS): m/z = 213.0, 215.0 ([M+H]+).
References
[1] Patent: WO2012/76430, 2012, A1. Location in patent: Page/Page column 90
[2] Patent: WO2006/38116, 2006, A2. Location in patent: Page/Page column 21
[3] Patent: WO2010/7100, 2010, A1. Location in patent: Page/Page column 40-41
[4] Patent: US2012/142665, 2012, A1. Location in patent: Page/Page column 17
[5] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 129
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Suppliers
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View Lastest Price from 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine manufacturers
- Product
- 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08