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ChemicalBook > CAS DataBase List > 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine

7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Application
Product Name
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS No.
882521-63-3
Chemical Name
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Synonyms
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amin;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;2-AMino-7-broMo-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 7-bromo-;7-Bromo-1,2,4 Triazolo [1,5-A] Pyridine-2-amine;7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;7-bromo-[1,2,4triazole combined[1,5-A]pyridine-2-amine;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine ISO 9001:2015 REACH
CBNumber
CB81560271
Molecular Formula
C6H5BrN4
Formula Weight
213.03
MOL File
882521-63-3.mol
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7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Property

Density 
2.09±0.1 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
4.30±0.30(Predicted)
form 
solid
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C6H5BrN4/c7-4-1-2-11-5(3-4)9-6(8)10-11/h1-3H,(H2,8,10)
InChIKey
DAYYXZOMYRSLBX-UHFFFAOYSA-N
SMILES
C12=NC(N)=NN1C=CC(Br)=C2
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Safety

WGK Germany 
3
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00258
Product name
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Purity
Aldrich
Packaging
1g
Price
$330
Updated
2025/07/31
TRC
Product number
B614675
Product name
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
B614675
Product name
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Packaging
500mg
Price
$240
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-9-0W
Product name
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Packaging
1g
Price
$247
Updated
2021/12/16
Matrix Scientific
Product number
115574
Product name
7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Purity
95%
Packaging
1g
Price
$322
Updated
2021/12/16
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7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Chemical Properties,Usage,Production

Application

7-Bromo-[1,2,4]triazolo[1,5-A]pyridine-2-amine is an organic intermediate that can be prepared by first preparing 1-ethoxycarbonyl-3-(4-bromo-pyridin-2-yl)-thiourea from 4-bromopyridine-2-amine and 4-bromopyridine-2-amine, and then reacting it with hydroxylamine hydrochloride to obtain 7-bromo-[1,2,4]triazolo[1,5-a]pyridine-2-amine.

Synthesis

882521-62-2

882521-63-3

1-Ethoxycarbonyl-3-(4-bromopyridin-2-yl)thiourea (17.5 g, 57.5 mmol) was mixed with hydroxylamine hydrochloride (20.0 g, 288 mmol) and N-ethyl diisopropylamine (30.1 ml, 173 mmol) in ethanol (367 ml). After stirring for a few minutes at room temperature, the reaction mixture was heated to reflux for 24 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. Water (100 ml) was added to the residue and stirred for 10 min to form a suspension. The solid product was collected by filtration, washed with water and dried to give 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine (10.71 g, 87.4% yield) as a light yellow solid. Melting point: 190-192°C. Mass spectrum (MS): m/z = 213.0, 215.0 ([M+H]+).

References

[1] Patent: WO2012/76430, 2012, A1. Location in patent: Page/Page column 90
[2] Patent: WO2006/38116, 2006, A2. Location in patent: Page/Page column 21
[3] Patent: WO2010/7100, 2010, A1. Location in patent: Page/Page column 40-41
[4] Patent: US2012/142665, 2012, A1. Location in patent: Page/Page column 17
[5] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 129

7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine manufacturers

Dideu Industries Group Limited
Product
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-27
Career Henan Chemical Co
Product
7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-08

882521-63-3, 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amineRelated Search:


  • 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
  • 2-AMino-7-broMo-[1,2,4]triazolo[1,5-a]pyridine
  • [1,2,4]Triazolo[1,5-a]pyridin-2-amine, 7-bromo-
  • 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine ISO 9001:2015 REACH
  • 7-Bromo-[1,2,4]triazolo[1,5-<i>a</i>]pyridin-2-amine
  • 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amin
  • 7-bromo-[1,2,4triazole combined[1,5-A]pyridine-2-amine
  • 7-Bromo-1,2,4 Triazolo [1,5-A] Pyridine-2-amine
  • 882521-63-3