Naxitamab

Product Name: Naxitamab
CAS No.: 1879925-92-4
Chemical Name: Naxitamab
Synonyms: Naxitamab;Naxitamab (anti-GD2);Research Grade Naxitamab;Research Grade Naxitamab(DGK07803);Naxitamab-gqgk|||Humanized 3F8|||Hu3F8
CBNumber: CB38081123
Formula Weight: 0
MOL File: Mol file

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Naxitamab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Naxitamab Chemical Properties,Usage,Production

Uses

Naxitamab (Hu3F8) is a humanized monoclonal antibody targeting the disialoganglioside GD2. Naxitamab can be used in research of neuroblastoma, osteosarcoma and other GD2-positive cancers[1].

in vivo

Naxitamab (Hu3F8; 100 mg/kg; i.v.; twice a week, for 4 weeks; athymic nude mice with LAN-1 xenografts) inhibits tumor growth in neuroblastoma xenografts^[1].

Animal Model:	Female athymic nude mice with LAN-1 xenografts^[1]
Dosage:	100 mg/kg
Administration:	Intravenous injection; twice a week, for 4 weeks
Result:	Inhibited tumor growth and prolonged the survival time.

References

[1] Cheung NK, et, al. Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo. Oncoimmunology. 2012 Jul 1;1(4):477-486. DOI:10.4161/onci.19864
[2] Markham A. Naxitamab: First Approval. Drugs. 2021 Feb;81(2):291-296. DOI:10.1007/s40265-021-01467-4

Naxitamab Preparation Products And Raw materials

Raw materials

Preparation Products

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Naxitamab Suppliers

China 19 United States 2 Global 21

Shanghai YuanYe Biotechnology Co., Ltd.

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1879925-92-4, NaxitamabRelated Search:

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Naxitamab

Research Grade Naxitamab(DGK07803)

Naxitamab (anti-GD2)

Naxitamab-gqgk|||Humanized 3F8|||Hu3F8

Research Grade Naxitamab

1879925-92-4