1-(2-Furoyl)piperazine

Product Name: 1-(2-Furoyl)piperazine
CAS No.: 40172-95-0
Chemical Name: 1-(2-Furoyl)piperazine
Synonyms: AKOS BB/0087;AKOS B003992;AKOS BBS-00003689;BIO-FARMA BF003584;TIMTEC-BB SBB003747;RARECHEM AH CK 0108;N-Furoyl piperazine;2-furoic piperazide;Terazosin Impurity10;2-(2-FUROYL)PIPERAZINE
CBNumber: CB3853599
Molecular Formula: C9H12N2O2
Formula Weight: 180.2
MOL File: 40172-95-0.mol

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1-(2-Furoyl)piperazine Property

Melting point:: 67-70 °C(lit.)
Boiling point:: 137-140°C 0,1mm
Density: 1.1819 (rough estimate)
refractive index: 1.5373 (estimate)
Flash point:: >230 °F
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform, Methanol (Slightly)
pka: 8.37±0.10(Predicted)
color: White to Pale Yellow
Sensitive: Hygroscopic
BRN: 880196
Stability:: Very Hygroscopic
CAS DataBase Reference: 40172-95-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
F: 10-34
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3100
Product name: Prazosin Related Compound D
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50MG
Price: $485
Updated: 2024/03/01

Sigma-Aldrich

Product number: 558966
Product name: 1-(2-Furoyl)piperazine
Purity: 97%
Packaging: 25g
Price: $133
Updated: 2023/06/20

Sigma-Aldrich

Product number: Y0000623
Product name: Terazosin impurity L
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000623
Price: $149
Updated: 2023/01/07

Alfa Aesar

Product number: A16773
Product name: 1-(2-Furoyl)piperazine, 98%
Packaging: 25g
Price: $65.5
Updated: 2021/12/16

Alfa Aesar

Product number: A16773
Product name: 1-(2-Furoyl)piperazine, 98%
Packaging: 100g
Price: $188
Updated: 2021/12/16

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1-(2-Furoyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow solid

Uses

2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Uses

1-(2-Furoyl)piperazine may be used to synthesize:

2-[4-(2-furoyl) piperazin-1-yl]-4-amino-6-benzyloxy-7-methoxyquinazoline hydrochloride monohydrate
2-[4-(2-furoyl)piperazin-1-yl]-4-amino-7-benzyloxy-6-methoxyquinazoline hydrochloride monohydrate
4-amino-2-[4-(2-furoyl)piperazin-1-yl]-quinazoline hydrochloride
6,7-dimethoxy-2-[4-(2-furoyl)-piperazin-1-yl]quinazoline-4-one hydrate
1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-furoyl)-piperazine hydrogen oxalate
1-(3,4-dichlorobenzyl)-4-(2-furoyl)-piperazine hydrogen oxalate
4-(9-fluorenyl)-1-(2-furoyl)piperazine
2-[4-(2-furoyl)piperazin-1-yl]-benzimidazole hydrochloride hydrate

Uses

2-Furanyl-1-piperazinylmethanone was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031

1-(2-Furoyl)piperazine Preparation Products And Raw materials

Raw materials

2-Furoic acid Toluene Di-tert-butyl dicarbonate Triethylamine Piperazine Dichloromethane Sodium hydroxide Thionyl chloride

Preparation Products

Prazosin

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1-(2-Furoyl)piperazine Suppliers

Belgium 3 Canada 3 China 127 Europe 2 France 2 Germany 11 India 35 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 16 United States 41 Global 248

Creasyn Finechem(Tianjin) Co., Ltd.

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J & K SCIENTIFIC LTD.

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INTATRADE GmbH

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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Energy Chemical

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Capot Chemical Co., Ltd

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View Lastest Price from 1-(2-Furoyl)piperazine manufacturers

Career Henan Chemical Co

Product: 1-(2-Furoyl)piperazine 40172-95-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2019-08-30

40172-95-0, 1-(2-Furoyl)piperazineRelated Search:

N-Aminoethylpiperazine 2-Ethylhexyl ferulate Piperazine Piperacillin 1-(Tetrahydro-2-Furoyl)Piperazine,TerazosinHcl,,1-(TETRAHYDRO-2-FUROYL)PIPERAZINE,N-(TETRAHYDRO-2-FUROYL)-PIPERAZINE 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine monohydrochloride Terazosin impurity 2-Piperazine-4-amino-6,7-dimethoxyquinazoline (R)-Terazosin 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine] 1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone 6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone NSC 351869 [4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin hydrochloride dihydrate Terazosin IMpurity J

BIO-FARMA BF003584

(FURAN-2-YL)(PIPERAZIN-1-YL)METHANONE

1-(2-FURANYLCARBONYL)-PIPERAZINE

1-(2-FUROYL)PIPERAZINE

AKOS BBS-00003689

AKOS B003992

AKOS BB/0087

N-(2-FUROYL)PIPERAZINE

RARECHEM AH CK 0108

TIMTEC-BB SBB003747

2-(2-FUROYL)PIPERAZINE

N-Furoyl piperazine

1-(2-FUROYL)-PIPERAZINE 97%

2-furoic piperazide

1-(2-Furoyl)piperazine,98%

Piperazine, 1-(2-furanylcarbonyl)-

(2-Furyl)(piperazino) ketone

Piperazino 2-furyl ketone

Piperazino(2-furanyl) ketone

Piperazino(2-furyl) ketone

1-(2-Furoyl)-piperazine ,97%

Prazosin EP IMpurity D

2-Furanyl-1-piperazinylmethanone

1-(2-Furoyl)piperazine96%

N-(2-Furoyl) piperazine 1-(2-Furoyl) piperazine

Terazosin EP Impurity L

Terazosin Impurity 12(Terazosin EP Impurity L)

Terazosin Impurity10

Prazosin Impurity 4(Prazosin EP Impurity D)

1-(furan-2-carbonyl)piperazine

Terazosin EP Impurity L (Prazosin EP Impurity D)

Prazosin EP Impurity D (Terazosin EP Impurity L)

Methanone, 2-furanyl-1-piperazinyl-

40172-95-0 1-(2-Furoyl)piperazine

Terazosin Hydrochloride Dihydrate EP Impurity L

Prazosin Hydrochloride Impurity D

Terazosin Hydrochloride Dihydrate Impurity L

40172-95-0

Heterocyclic Building Blocks

Piperazines

Building Blocks

BUILDING BLOCKS

API intermediates

Piperidines, Piperidones, Piperazines