ChemicalBook > CAS DataBase List > metiazinic acid
metiazinic acid
- Product Name
- metiazinic acid
- CAS No.
- 13993-65-2
- Chemical Name
- metiazinic acid
- Synonyms
- Metian;Soripal;RP 16091;Ambrunate;Novartril;Soridermal;Metiazinic;metiazinic acid;(10-METHYL2-PHENOTHIAZINYL)ACETICACID;10H-Phenothiazine-2-acetic acid, 10-methyl-
- CBNumber
- CB3889277
- Molecular Formula
- C15H13NO2S
- Formula Weight
- 271.33
- MOL File
- 13993-65-2.mol
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metiazinic acid Property
- Melting point:
- 146℃
- Boiling point:
- 482.6±44.0 °C(Predicted)
- Density
- 1.2237 (rough estimate)
- refractive index
- 1.7500 (estimate)
- pka
- 4.12±0.10(Predicted)
- Water Solubility
- 31mg/L(30 ºC)
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Safety
- Toxicity
- LD50 in mice, rats (mg/kg): 800, ~500 orally (Joulou)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0003349
- Product name
- METIAZINIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.29
- Updated
- 2021/12/16
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metiazinic acid Chemical Properties,Usage,Production
Originator
Soripan,Specia,France,1970
Definition
ChEBI: Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.
Manufacturing Process
10-Methyl-3-acetylphenthiazine is prepared in accordance with G. Cauquil and A. Casadevall, Bull. Soc.Chim., p 768 (1955). (10-Methyl-3-phenthiazinyl)acetic acid (MP 146°C; 21.4 g) is prepared by Willgerodt's reaction (action of sulfur and morpholine, followed by hydrolysis) employing 10-methyl-3-acetylphenthiazine as starting material.
Therapeutic Function
Antiinflammatory
Trade name
Roimal (Kantoishi, Japan), Soripal (Torii, Japan).
Synthesis
Metiazinic acid is prepared via
the Willgerodt reaction (sulfur and morpholine)
from 2-acetyl-10-methylphenothiazine.
Dosage
Metiazinic acid has been beneficial to arthritis patients when given at a daily dose of 0.75 – 1.5 g/d.
metiazinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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metiazinic acid Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32165
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19711
- Advantage
- 58
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19885
- Advantage
- 58
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