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4-MERCAPTOPHENYLACETIC ACID

Product Name
4-MERCAPTOPHENYLACETIC ACID
CAS No.
39161-84-7
Chemical Name
4-MERCAPTOPHENYLACETIC ACID
Synonyms
MPAA;4-MERCAPTOBENZENEACETATE;4-MERCAPTOPHENYLACETIC ACID;p-Mercaptophenylacetic Acid;2-(4-sulfanylphenyl)aceticaci;Benzeneacetic acid,4-mercapto-;4-Mercaptophenylacetic acid 97%;2-(4-sulfanylphenyl)acetic acid;4-Mercaptophenylacetic Acid ( MPAA);4-Mercaptophenylacetic acid≥ 98% (HPLC)
CBNumber
CB3276163
Molecular Formula
C8H8O2S
Formula Weight
168.21
MOL File
39161-84-7.mol
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4-MERCAPTOPHENYLACETIC ACID Property

Melting point:
105-109 °C (lit.)
Boiling point:
336.0±17.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly), DMSO (Slightly)
pka
4.21±0.10(Predicted)
form 
Solid
color 
Off-White
Water Solubility 
Slightly soluble in water. Soluble in Dichloromethane, Ethanol and Methanol
Sensitive 
Air Sensitive
InChI
InChI=1S/C8H8O2S/c9-8(10)5-6-1-3-7(11)4-2-6/h1-4,11H,5H2,(H,9,10)
InChIKey
ORXSLDYRYTVAPC-UHFFFAOYSA-N
SMILES
C1(CC(O)=O)=CC=C(S)C=C1
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-36/37/39
RIDADR 
UN 3335
WGK Germany 
3
HS Code 
2930909899
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
653152
Product name
4-Mercaptophenylacetic acid
Purity
97%
Packaging
1g
Price
$112
Updated
2025/07/31
Sigma-Aldrich
Product number
653152
Product name
4-Mercaptophenylacetic acid
Purity
97%
Packaging
5g
Price
$309
Updated
2025/07/31
TCI Chemical
Product number
M2601
Product name
2-(4-Mercaptophenyl)acetic Acid
Packaging
1G
Price
$96
Updated
2025/07/31
TCI Chemical
Product number
M2601
Product name
2-(4-Mercaptophenyl)acetic Acid
Packaging
5G
Price
$288
Updated
2025/07/31
AK Scientific
Product number
5630AH
Product name
4-Mercaptophenylacetic acid
Packaging
5g
Price
$293
Updated
2021/12/16
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4-MERCAPTOPHENYLACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

4-MERCAPTOPHENYLACETIC ACID is White Powder

Uses

4-MERCAPTOPHENYLACETIC ACID is a redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents.

Uses

4-Mercaptophenylacetic acid has been used in the preparation of small ubiquitin-like modifier peptides from bis(2-sulfanylethyl)amido peptide via sequential native chemical ligation.
It can be used:

  • On-resin preparation of peptide-α thiophenylesters which are used in a chemical ligation process for the chemical synthesis of peptides.
  • In one pot deprotection of (acetamido-methyl)cysteine following native chemical ligation and/or desulfurization method for the preparation of peptides.
  • Palladium facilitated deprotection of N-terminal cysteine through native chemical ligation method for the preparation of synthetically challenging proteins.

4-MERCAPTOPHENYLACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-MERCAPTOPHENYLACETIC ACID Suppliers

Shanghai QiQiao Biological Technology Co., Ltd.
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021-37653318; 15221675714
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515366396@qq.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
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Alfa Aesar
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400-6106006
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021-67582001/03/05
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saleschina@alfa-asia.com
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China
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Energy Chemical
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Nanjing Chemlin Chemical Co., Ltd
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+86-25-83453306
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Chemsky(shanghai)International Co.,Ltd.
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Syntechem Co.,Ltd
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E-Mail Inquiry
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info@syntechem.com
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China
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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sales@heowns.com
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China
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View Lastest Price from 4-MERCAPTOPHENYLACETIC ACID manufacturers

Shanghai Rlavie Technology Co ltd
Product
4-Mercaptophenylacetic acid 39161-84-7
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-01-03

39161-84-7, 4-MERCAPTOPHENYLACETIC ACIDRelated Search:


  • 4-MERCAPTOBENZENEACETATE
  • 4-MERCAPTOPHENYLACETIC ACID
  • 4-Mercaptophenylacetic Acid ( MPAA)
  • 2-(4-sulfanylphenyl)acetic acid
  • MPAA
  • 4-Mercaptophenylacetic acid 97%
  • 4-Mercaptophenylacetic acid≥ 98% (HPLC)
  • Benzeneacetic acid,4-mercapto-
  • p-Mercaptophenylacetic Acid
  • 2-(4-sulfanylphenyl)aceticaci
  • ORGANIC CHEMICALS- 4-MERCAPTOPHENYLACETIC ACID
  • 39161-84-7
  • HSC6H4CH2CO2H
  • Building Blocks
  • Sulfur Compounds
  • Thiols/Mercaptans
  • Organic Building Blocks
  • Aromatic Phenylacetic Acids and Derivatives
  • Intermediates
  • Sulfur & Selenium Compounds
  • Organic Building Blocks
  • Sulfur Compounds
  • Thiols/Mercaptans