ChemicalBook > CAS DataBase List > 2-[2-(2-methoxyethoxy)ethoxy]ethylamine

2-[2-(2-methoxyethoxy)ethoxy]ethylamine

Product Name
2-[2-(2-methoxyethoxy)ethoxy]ethylamine
CAS No.
74654-07-2
Chemical Name
2-[2-(2-methoxyethoxy)ethoxy]ethylamine
Synonyms
2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine;MPEG3-NH2;NH3-PEG3-OME;m-PEG3-Amine;MeO-PEG3-NH2;Methyl-PEG3-amine;H2N-(CH2CH2O)3-Me;3,6,9-Trioxa-1-aminodecane;3,6,9-Trioxadecane-1-amine;2,5,8-trioxatridecane-10-aMine
CBNumber
CB3899124
Molecular Formula
C7H17NO3
Formula Weight
163.21
MOL File
74654-07-2.mol
More
Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Property

Boiling point:
106℃ (11 Torr)
Density 
0.978±0.06 g/cm3(Predicted)
refractive index 
1.4395 (589.3 nm 20℃)
storage temp. 
2-8°C
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Oil
pka
8.74±0.10(Predicted)
color 
Colorless to light yellow
InChI
InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
InChIKey
OKUWOEKJQRUMBW-UHFFFAOYSA-N
SMILES
C(N)COCCOCCOC
More
Less

Safety

HS Code 
2922190090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901158
Product name
2-(2-(2-Methoxyethoxy)ethoxy) ethanamine
Purity
≥95%
Packaging
5G
Price
$332
Updated
2025/07/31
TCI Chemical
Product number
M3686
Product name
m-PEG3-Amine
Purity
min. 95.0 %
Packaging
200MG
Price
$90
Updated
2025/07/31
TCI Chemical
Product number
M3686
Product name
m-PEG3-Amine
Purity
min. 95.0 %
Packaging
1G
Price
$270
Updated
2025/07/31
TRC
Product number
M220438
Product name
2-(2-(2-Methoxyethoxy)ethoxy)ethanamine
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
M220438
Product name
2-(2-(2-Methoxyethoxy)ethoxy)ethanamine
Packaging
2.5g
Price
$175
Updated
2021/12/16
More
Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Chemical Properties,Usage,Production

Description

m-PEG3-amine is a PEG reagent containing an amino group (NH2). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-amine whose chemical name 2-[2-(2-methoxyethoxy)ethoxy]ethylamine,it is a PROTAC bridge, belonging to the PEG class, which can be used to synthesize a series of PROTAC molecules, and can also be used for the synthesis of antibody drug conjugates (ADCs).

Synthesis

2-[2-(2-methoxyethoxy)ethoxy]ethylamine is an organic intermediate, which can be prepared from triethylene glycol monomethyl ether as raw material to prepare 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate, and then Reaction with sodium azide,and then Reacts with sodium azide to finally yield 3,6,9-trioxa-1-aminodecane.

IC 50

Cleavable Linker; PEGs

References

[1] Patent: WO2015/191433, 2015, A1. Location in patent: Paragraph 0041
[2] Chemische Berichte, 1980, vol. 113, # 5, p. 1691 - 1707
[3] Molecules, 2015, vol. 20, # 9, p. 16085 - 16102
[4] Chemistry - An Asian Journal, 2011, vol. 6, # 1, p. 149 - 156
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 48, p. 15461 - 15465

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Suppliers

China 153 Germany 1 India 2 United Kingdom 1 United States 13 Global 170
Suzhou Greet Medical Technology Co., Ltd.
Tel
0512-62384765 13701544574
Email
renwei@great-chem.cn
Country
China
ProdList
77
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
Advantage
59
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
Advantage
58
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
43
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
354
Advantage
60
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7782
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
SunaTech Inc.
Tel
0512-62872180 18994314770
Fax
+86 512 62872181
Email
sales@sunatech.com
Country
China
ProdList
1182
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Shanghai Boka-chem Tech. Inc.
Tel
400-026-1533/(021) 6478-0600
Fax
+86 (21) 6459-2060
Email
sales@bokachem.com
Country
China
ProdList
876
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
JinJin Le Chemical Co., Ltd
Tel
18001959627(微信同号) 18001959627
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd
Tel
021-50929289 18616309303
Fax
-
Email
sales@ypptech.com.cn
Country
China
ProdList
287
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9751
Advantage
58
Wuxi AppTec
Tel
022-59987777 13552403979
Email
jia_guoqiang@wuxiapptec.com
Country
China
ProdList
22345
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Shanghai 9i Technology Co., Ltd.
Tel
021-33555271 18201009191
Fax
021-33555271
Email
MWen@9iLab.com
Country
China
ProdList
133
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9717
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Linyi Azelasi Biological Co., Ltd.
Tel
17753923223
Fax
0539-6222546
Email
2805221329@qq.com
Country
China
ProdList
1474
Advantage
58
Zhengzhou Ruke Biological Co., Ltd.
Tel
15981811963
Fax
QQ：1410472904
Email
1410472904@qq.com
Country
China
ProdList
5825
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9988
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
More
Less

View Lastest Price from 2-[2-(2-methoxyethoxy)ethoxy]ethylamine manufacturers

LAURENT
Product
mPEG3-NH2 74654-07-2
Price
US $4560.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
300kg
Release date
2025-11-20
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
m-PEG3-Amine 74654-07-2
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-06
Xian confluore Biological Technology Co., Ltd.
Product
m-PEG3-amine 74654-07-2
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-27

74654-07-2, 2-[2-(2-methoxyethoxy)ethoxy]ethylamineRelated Search:

OCTAETHYLENE GLYCOL MONOMETHYL ETHER Methyl-PEG3-MS Methyl-PEG9-t-butyl ester 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Nonaethylene glycol HEXAETHYLENE GLYCOL MONOMETHYL ETHER BIOTIN-XX-NHS H2N-PEG24-tBu 2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol Boc-1-amino-3,6-dioxa-8-octanediamine 2-(2-Methoxyethoxy)ethanamine alpha, oMega-Dipropionic acid triethylene glycol HS-PEG8-CH2CH2COOH 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol DODECAETHYLENE GLYCOL alpha-aMine-oMega-propionic acid octaethylene glycol N3-PEG6-tBu Amino-PEG2-acid

  • 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
  • 2-[2-(2-Methoxyethoxy)ethoxy]ethanamine
  • 3,6,9-Trioxadecane-1-amine
  • 2,5,8-trioxatridecane-10-aMine
  • MPEG3-NH2
  • EthanaMine,2-[2-(2-Methoxyethoxy)ethoxy]-
  • 3,6,9-Trioxa-1-aminodecane
  • Methyl-PEG3-amine
  • m-PEG3-Amine
  • NH3-PEG3-OME
  • 2-(2-(2-Methoxyethoxy)ethoxy) ethanamine >=95%
  • MeO-PEG3-NH2
  • 2-(2-(2-Methoxyethoxy)ethoxy)-eth
  • 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine
  • H2N-(CH2CH2O)3-Me
  • mPEG3-NH2/Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-
  • 74654-07-2
  • MeO-PEG-NH2
  • peg