Amino-PEG2-acid

Product Name: Amino-PEG2-acid
CAS No.: 791028-27-8
Chemical Name: Amino-PEG2-acid
Synonyms: NH2-PEG2-COOH;H2N-PEG2-CH2CH2COOH;Amino-PEG2-C2-acid;Amino-PEG2-COOH;AMINE-PEG2-COOH;Amino-PEG2-acid;Amino-PEG2-propionic acid;H2N-(CH2CH2O)2-CH2CH2COOH;Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL;3-[2-(2-Aminoethoxy)ethoxy]-propanoic acid
CBNumber: CB62501433
Molecular Formula: C7H15NO4
Formula Weight: 177.2
MOL File: 791028-27-8.mol

More

Less

Amino-PEG2-acid Property

Boiling point:: 331.5±27.0 °C(Predicted)
Density: 1.142±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 4.27±0.10(Predicted)

More

Less

Safety

HS Code: 2918999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A577183
Product name: Amino-PEG2Acid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A577183
Product name: Amino-PEG2Acid
Packaging: 100mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP73006
Product name: 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid
Packaging: 250mg
Price: $160
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP73006
Product name: 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid
Packaging: 50mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP73006
Product name: 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid
Packaging: 100mg
Price: $80
Updated: 2021/12/16

More

Less

Amino-PEG2-acid Chemical Properties,Usage,Production

Description

Amino-PEG2-acid is a PEG reagent containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADClinker for the synthesis of antibody-drug conjugated Ck (ADC). It is also a PEG-based PROTAClinker that can be used for PROTAC synthesis.

in vivo

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Amino-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Amino-PEG2-acid Suppliers

China 106 India 1 United Kingdom 2 United States 10 Global 119

Nanjing Anyan Pharmaceutical Technology Co. , Ltd.

Tel: 18136859766
Fax: QQ3209878052
Email: amy.xiang@ally-chem.com
Country: China
ProdList: 330
Advantage: 60

Shanghai Huici Pharmaceutical Technology Co., LTD

Tel: 19372841038 19372841038
Email: lixing@pharmahuici.com
Country: China
ProdList: 216
Advantage: 58

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Sichuan Tongsheng Amino acids Co.,Ltd.

Tel: 0838-2809458 13350585791
Fax: +86-838-2274207
Email: pharm@biots.cn
Country: China
ProdList: 348
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3296
Advantage: 57

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6854
Advantage: 65

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8618575662672 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9747
Advantage: 57

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 479
Advantage: 58

More

Less

View Lastest Price from Amino-PEG2-acid manufacturers

airuikechemical co., ltd.

Product: α-amine-ω-propionic acid diethylene glycol 791028-27-8
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Xian confluore Biological Technology Co., Ltd.

Product: Amino-PEG2-COOH 791028-27-8
Price: US $0.00/mg
Min. Order: 250mg
Purity: >98.00%
Supply Ability: 250mg
Release date: 2024-03-22

Career Henan Chemical Co

Product: α-amine-ω-propionic acid diethylene glycol 791028-27-8
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

791028-27-8, Amino-PEG2-acidRelated Search:

α,ω-dipropionic acid tetraethylene glycol Biotin-PEG6-OH H2N-PEG8-tBu alpha-aMine-oMega-propionic acid triethylene glycol 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid 2,5,8,11,14,17-Hexaoxanonadecan-19-amine MPEG16-NH2 TETRAETHYLENEGLYCOL MONOMETHYL ETHER N3-PEG3-tBu 2,5,8,11,14-Pentaoxahexadecan-16-amine 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine alpha-aMine-oMega-propionic acid dodecaethylene glycol HEPTAETHYLENE GLYCOL MONOMETHYL ETHER 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AMINE O-METHYL-UNDECAETHYLENE GLYCOL Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Amino-PEG4-acid

α-amine-ω-propionic acid diethylene glycol

alpha-aMine-oMega-propionic acid diethylene glycol

H2N-PEG2-CH2CH2COOH

3-[2-(2-Aminoethoxy)ethoxy]-propanoic acid

Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL

Amino-PEG2-acid

NH2-PEG2-COOH

Amino-PEG2-propionic acid

H2N-PEG2-CH2CH2COOH

AMINE-PEG2-COOH

Amino-PEG2-COOH

Amino-PEG2-C2-acid

Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]-

H2N-(CH2CH2O)2-CH2CH2COOH

α-Amine-ω-propionic acid diethylene glycol

H2N-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]-

791028-27-8

PEG-COOtBu

ADCs Linkers

peg