Dimethylenastron

Product Name: Dimethylenastron
CAS No.: 863774-58-7
Chemical Name: Dimethylenastron
Synonyms: enastron;Dimethylenastron;Eg5 Inhibitor III;Dimethylenastron, 10 mM in DMSO;Eg5 Inhibitor III(Dimethylenastron);Dimethylenastron - Eg5 inhibitor III;Inhibitor,Dimethylenastron,Kinesin,inhibit;Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem;2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone;4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one
CBNumber: CB41115853
Molecular Formula: C16H18N2O2S
Formula Weight: 302.39
MOL File: 863774-58-7.mol

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Dimethylenastron Property

Boiling point:: 475.6±55.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble15mg/mL, clear
pka: 9.59±0.10(Predicted)
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H360May damage fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 324622
Product name: Eg5 Inhibitor III, Dimethylenastron
Packaging: 5mg
Price: $432
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324622
Product name: Eg5 Inhibitor III, Dimethylenastron
Packaging: 1mg
Price: $154
Updated: 2023/01/07

Cayman Chemical

Product number: 22357
Product name: Dimethylenastron
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22357
Product name: Dimethylenastron
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0905
Product name: Dimethylenastron
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $108
Updated: 2022/05/15

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Dimethylenastron Chemical Properties,Usage,Production

Uses

Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells.

Biochem/physiol Actions

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays.

storage

Store at -20°C

Dimethylenastron Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethylenastron Suppliers

Americas 1 China 56 Europe 1 India 2 Japan 1 United Kingdom 2 United States 11 Global 74

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Cayman Chemical Company

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Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

MedChemExpress

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Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Combi-Blocks Inc.

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Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Axon Medchem LLC

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Fax: --
Email: info@axonmedchem.com
Country: United States
ProdList: 763
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

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View Lastest Price from Dimethylenastron manufacturers

Career Henan Chemical Co

Product: Dimethylenastron 863774-58-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-04

863774-58-7, DimethylenastronRelated Search:

SILICA Phenol Dimethylenastron

Dimethylenastron

2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone

Eg5 Inhibitor III(Dimethylenastron)

Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem

Dimethylenastron - Eg5 inhibitor III

Eg5 Inhibitor III

enastron

5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-

4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one

Inhibitor,Dimethylenastron,Kinesin,inhibit

Dimethylenastron, 10 mM in DMSO

863774-58-7