MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Product Name: MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
CAS No.: 65144-34-5
Chemical Name: MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
Synonyms: SPCK;HLE INHIBITOR;MEOSUC-AAPV-CMK;MEOSUC-APPV-CMK;ELASTASE INHIBITOR III;Elastase Inhibitor, SPCK;MEOSUC-ALA-ALA-PRO-VAL-CMK;N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone
CBNumber: CB4111744
Molecular Formula: C22H35ClN4O7
Formula Weight: 502.99
MOL File: 65144-34-5.mol

More

Less

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Property

Melting point:: 159-161 °C
Boiling point:: 809.4±65.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: ethanol: 50 mg/mL, clear, colorless
pka: 13.05±0.20(Predicted)
form: Solid
Sensitive: Moisture Sensitive
BRN: 6167019

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 5mg
Price: $170
Updated: 2024/03/01

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 10mg
Price: $291
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324745
Product name: Elastase Inhibitor III
Purity: The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Packaging: 5MG
Price: $238
Updated: 2023/06/20

Alfa Aesar

Product number: J65894
Product name: Elastase Inhibitor III
Packaging: 5mg
Price: $123
Updated: 2021/12/16

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 25mg
Price: $549
Updated: 2024/03/01

More

Less

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties,Usage,Production

Uses

A potent irreversible inhibitor of human leukocyte elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Suppliers

China 57 Germany 1 Switzerland 1 United Kingdom 2 United States 12 Global 73

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7298
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 6968
Advantage: 58

Nanchang Tianzhen Biotechnology Co., Ltd

Tel: 13173652190
Email: pomy@tanzhenbio.com
Country: China
ProdList: 1790
Advantage: 58

65144-34-5, MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONERelated Search:

Elastase 2-AMINO-1-PYRROLIDIN-1-YL-ETHANONE HCL N,N-DIETHYL-2-(METHYLAMINO)ACETAMIDE HYDROCHLORIDE N-ME-GLY-NME2 1-ACETAMIDO-ACETONE MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE H-ALA-PRO-NH2 HCL Methyl 4-aminobutyrate hydrochloride H-ALA-ALA-ALA-NH2 HCL 2-AMINO-N,N-DIETHYL-ACETAMIDE HCL N-(1-methyl-2-oxopropyl)acetamide ALA-ALA-PRO-VAL-CMK H-PRO-NHET HCL 2-METHYLAMINO-1-PYRROLIDIN-1-YL-ETHANONE X HCL >98% MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE

methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE

MEOSUC-APPV-CMK

MEOSUC-AAPV-CMK

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CMK

ELASTASE INHIBITOR III

HLE INHIBITOR

N-(methoxysuccinyl)-L-ala-L-ala-L-prol.-L-val-chlorome.ket.

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL*CHLORO METHYL KETO

N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&

N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine CMK

SPCK

Elastase Inhibitor, SPCK

methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone

methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate

L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]-

65144-34-5

C22H35ClN4O7

C22H35N4O7Cl

Biochemicals and Reagents

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Metalloproteinase Inhibitors

Cytoskeleton and Extracellular Matrix

Enzyme Inhibitors

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Extracellular Matrix

Substrate Analogs

ProteaseInhibitors