ChemicalBook > CAS DataBase List > (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID

Product Name
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
CAS No.
114457-94-2
Chemical Name
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
Synonyms
N-PyrazinyL;Bortezomib INT;Bortezomib INT B;Bortezomib impurity B;Bortezomib Acid Analog;Bortezomib impurity 92;N-(2-pyrazinylcarbonyl)-;Bortezomib Acid Impurity;Bortezomib Intermediate 2;Bortezomib USP Impurity D
CBNumber
CB41119462
Molecular Formula
C14H13N3O3
Formula Weight
271.27
MOL File
114457-94-2.mol
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(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Property

Melting point:
166-169℃
Boiling point:
573.8±50.0 °C(Predicted)
Density 
1.323
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol (Sparingly)
pka
13.93±0.46(Predicted)
form 
Solid
color 
White to Light Beige
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2068
Product name
N-(Pyrazinylcarbonyl)-L-phenylalanine
Purity
>98.0%(HPLC)
Packaging
1g
Price
$56
Updated
2024/03/01
TRC
Product number
P841500
Product name
N-Pyrazinylcarbonyl-L-phenylalanine
Packaging
250mg
Price
$95
Updated
2021/12/16
Usbiological
Product number
287137
Product name
N-Pyrazinylcarbonyl-L-phenylalanine
Packaging
100mg
Price
$305
Updated
2021/12/16
ChemScene
Product number
CS-W020144
Product name
(S)-3-Phenyl-2-[[(pyrazin-2-yl)carbonyl]amino]propanoicacid
Purity
99.74%
Packaging
1g
Price
$10
Updated
2021/12/16
ChemScene
Product number
CS-W020144
Product name
(S)-3-Phenyl-2-[[(pyrazin-2-yl)carbonyl]amino]propanoicacid
Purity
99.74%
Packaging
5g
Price
$40
Updated
2021/12/16
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(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Chemical Properties,Usage,Production

Chemical Properties

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID is Light Beige Solid

Uses

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID is used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Suppliers

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View Lastest Price from (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID 114457-94-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(S)-3-phenyl-2-(pyrazine-2-carboxamido)propanoic acid 114457-94-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000 KGS
Release date
2021-06-19
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID 114457-94-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-01

114457-94-2, (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACIDRelated Search:

Palladium (II) Acetate Phosphorus trichloride Ufiprazole L-Phenylalanine Sildenafil citrate 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- Bortezomib Impurity 45 BOC-D-Phenylalanine N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide BortezoMib IMpurity N Sildenafil ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Bortezomib 1-Chloro-2-methylpropane Bortezomib Impurity 5

  • (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
  • (S)-3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic acid
  • Bortezomib Intermediate 2
  • N-Pyrazinylcarbonyl-L-phenylalanine
  • N-(2-Pyrazinylcarbonyl)-L-phenylalanine
  • Bortezomib Acid Impurity
  • Bortezomib INT B
  • <i>N</i>-(Pyrazinylcarbonyl)-<small>L</small>-phenylalanine
  • (S)-3-Phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
  • N-(2-pyrazinylcarbonyl)-
  • BortezoMib IMpurity B ((S)-3-Phenyl-2-(pyrazine-2-carbonylaMino)propanoic Acid)
  • L-Phenylalanine, N-(2-pyrazinylcarbonyl)-
  • Bortezomib impurity B
  • Bortezomib INT
  • Bortezomib impurity 12/((S)-3-Phenyl-2-(pyrazine-2-carbonylamino)propanoic Acid
  • (2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanoic acid
  • (pyrazine-2-carbonyl)-L-phenylalanine
  • (S)-3-Phenyl-2-(pyrazine-2-carbox
  • 2-[[oxo(2-pyrazinyl)methyl]amino]-3-phenylpropanoic acid
  • N-PyrazinyL
  • Bortezomib USP Impurity D
  • N-((S)-1-(((S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3- phenylpropan-2-yl)pyrazine-2-carboxamide
  • (S)-3-Phenyl-2-[[(pyrazin-2-yl)carbonyl]amino]propanoic acid (Bortezomib Impurity)
  • Bortezomib Related Compund D/ Bortezomib Acid Analog
  • (R)-3-methyl-1-((3aS,4S,6S,7aS)-3a,5,5- trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1- amine
  • Bortezomib Acid Analog
  • (S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoicaci
  • (S)-3-phenyl-2-(pyrazine-5-carboxamido)propanoic acid
  • (S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid|||N-(Pyrazinylcarbonyl)-L-phenylalanine
  • Bortezomib impurity 92
  • 114457-94-2
  • 114459-94-2
  • 1144557-94-2
  • Amino Acids & Derivatives
  • Aromatics