Z-9-DODECEN-1-YL ACETATE Property

Boiling point:

300.1±21.0℃ (760 Torr)

Density 

0.881±0.06 g/cm3 (20 ºC 760 Torr)

refractive index 

1.4439 (22℃)

Flash point:

96.5±20.4℃

LogP

5.504 (est)

EPA Substance Registry System

(Z)-9-Dodecen-1-ol acetate (16974-11-1)

Safety

Toxicity

LD50 oral in rat: > 5gm/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Z-9-DODECEN-1-YL ACETATE Chemical Properties,Usage,Production

Uses

(9Z)-Dodecen-1-ol Acetate is derived from 2-Decyn-1-ol (D228475), which is used in the synthesis of antitumor agents, isomers of Panaxytriol and Falcarinol (F101100). Also used in the synthesis of aromatase inhibitors used in the treatment of cancers, primarily breast and ovarian.

Definition

ChEBI: 9Z-Dodecenyl acetate is a carboxylic ester.

Synthesis Reference(s)

Tetrahedron Letters, 21, p. 1433, 1980 DOI: 10.1016/S0040-4039(00)92738-2