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Deoxycorticosterone acetate

Product Name
Deoxycorticosterone acetate
CAS No.
56-47-3
Chemical Name
Deoxycorticosterone acetate
Synonyms
doxo;DOCA;arcort;steraq;cortate;ocriten;syncort;Decorten;cortacet;cortenil
CBNumber
CB3462948
Molecular Formula
C23H32O4
Formula Weight
372.5
MOL File
56-47-3.mol
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Deoxycorticosterone acetate Property

Melting point:
157°C
alpha 
D20 +168 to +176° (dioxane)
Boiling point:
421.94°C (rough estimate)
Density 
1.0415 (rough estimate)
refractive index 
175 ° (C=1, Dioxane)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: insoluble
color 
White to Off-White
Water Solubility 
4mg/L(25 ºC)
Merck 
2901
BRN 
2570798
InChI
InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
InChIKey
VPGRYOFKCNULNK-ACXQXYJUSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2
LogP
3.080
CAS DataBase Reference
56-47-3(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
RIDADR 
UN 2811
WGK Germany 
3
RTECS 
HG0525000
HazardClass 
IRRITANT
HS Code 
2937290000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
1g
Price
$207
Updated
2024/03/01
Sigma-Aldrich
Product number
1174001
Product name
Deoxycorticosterone acetate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$174.4
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
5g
Price
$673
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
25g
Price
$1590
Updated
2024/03/01
Sigma-Aldrich
Product number
D0400000
Product name
Desoxycortone acetate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
d0400000
Price
$220
Updated
2024/03/01
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Deoxycorticosterone acetate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Adrenocortical/mineralocorticoid Steroid.

Uses

Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

Definition

ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.

brand name

Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].

General Description

Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.

Purification Methods

11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]

Deoxycorticosterone acetate Preparation Products And Raw materials

Raw materials

Dry acetone Calcium oxide Progesterone Tetrahydrofuran Potassium Acetate

Preparation Products

5A-PREGNAN-21-OL-3-20-DIONE CRYSTALLINE
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Deoxycorticosterone acetate Suppliers

Canada 1 China 184 Europe 3 France 3 Germany 4 India 8 Japan 3 Russia 1 Switzerland 1 United Kingdom 12 United States 36 Global 256
Wuhan Dingtong Pharmaceutical Co., Ltd
Tel
027-027-59207795 18327179646
Fax
027-59207795
Email
18327179646@163.com
Country
China
ProdList
1959
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel
18858184290; 18858184290
Fax
0086-571-28313105
Email
sales@zyterpharm.com
Country
China
ProdList
48
Advantage
49
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
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RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
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View Lastest Price from Deoxycorticosterone acetate manufacturers

Nantong Guangyuan Chemicl Co,Ltd
Product
corticosterone 56-47-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-02
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
Deoxycorticosterone acetate 56-47-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50tons
Release date
2023-08-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
Deoxycorticosterone acetate 56-47-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

56-47-3, Deoxycorticosterone acetate Related Search:

Ethyl acetate Cellulose acetate Desoxycorticosterone CHLOROPHOSPHONAZO III Chenodeoxycholic acid CORTICOSTERONE POLY(VINYL ACETATE) Vinyl acetate Glatiramer acetate Ammonium acetate Epiandrosterone acetate Ursodeoxycholic acid Sodium acetate 16-Dehydropregnenolone acetate ACETATE (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Hydrocortisone sodium succinate REICHSTEIN'S SUBSTANCE S 21-ACETATE

  • 21-HYDROXYPROGESTERONE 21-ACETATE VETRAN
  • 11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate
  • 21-Acetoxypregn-4-en-3,20-dione
  • 21-Hydroxypregn-4-ene-3,20-dione Acetate
  • Decorten
  • Decosteron
  • DEOXYCORTICOSTERONE ACETATE(RG)
  • Desoxycorticosterone Acetate (200 mg)
  • 3,20-Dioxopregn-4-en-21-yl acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
  • DOCA(Deoxycorticosterone acetate)
  • arcort
  • bio-corten
  • cortacet
  • cortate
  • cortenil
  • cortesan
  • cortifar
  • cortigen
  • cortinaq
  • cortiron
  • cortivis
  • cortixyl
  • decosterone
  • decostrate
  • deoxy-corticosteronacetate
  • deoxycortoneacetate
  • descorterone
  • descotone
  • desoxycorticosterone-21-acetate
  • dorcostrin
  • doxo
  • doxycamon
  • krinocorts
  • ocriten
  • organon’sdocaacetate
  • percorten
  • percotol
  • Pregn-4-en-21-ol-3,20-dione21-acetate
  • primocort
  • primocortan
  • sincortex
  • steraq
  • syncort
  • syncorta
  • syncortyl
  • 11-DEOXYCORTICOSTERONE ACETATE; DOC ACETATE; CORTEXONE ACETATE
  • 4-pregnene-3,20-dione-21-olacetate
  • unidocan
  • 11-deoxycorticosterone21-acetate
  • 20-dione,21-hydroxy-pregn-4-ene-acetate
  • 21-acetoxy-3,20-diketopregn-4-ene
  • 21-Acetyloxypregn-4-ene-3,20-dione
  • 21-hydroxypregn-4-ene-3,20-dione21-acetate
  • 11-DEOXYCORTICOSTERONE ACETATE
  • 11-desoxycorticosterone acetate
  • 21-ACETOXYPROGESTERONE
  • 21-ACETOXY-4-PREGNENE-3,20-DIONE