Loperamide

Product Name: Loperamide
CAS No.: 106900-12-3
Chemical Name: Loperamide
Synonyms: R 58425;loperamide oxide;LoperaMide-d6 N-Oxide;Loperamide EP Impurity F;trans-Loperamide N-Oxide;Loperamide impurity-F(EP);Loperamide EP Impurity F HCl;Loperamide oxide monohydrate CRS;Loperamide USP Related Compound F;Loperamide Hydrochloride Impurity F
CBNumber: CB41179066
Molecular Formula: C29H33ClN2O3
Formula Weight: 493.04
MOL File: 106900-12-3.mol

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Loperamide Property

solubility: Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
pka: 12.94±0.20(Predicted)
Stability:: Hygroscopic

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Safety

RIDADR: UN 2811 6.1 / PGIII
RTECS: TM4960200
HS Code: 2933399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000341
Product name: Loperamide oxide monohydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000341
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2916
Product name: Loperamide Related Compound F
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $575
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP636
Product name: Loperamide N-oxide
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 25MG
Price: $273
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1370065
Product name: Loperamide oxide monohydrate
Packaging: 25mg
Price: $1490
Updated: 2024/03/01

TRC

Product number: L469460
Product name: trans-LoperamideN-Oxide
Packaging: 250mg
Price: $1040
Updated: 2021/12/16

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Loperamide Chemical Properties,Usage,Production

Chemical Properties

White or almost white powder, slightly hygroscopic.

Uses

Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Uses

Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Definition

ChEBI: Loperamide oxide is a diarylmethane.

Loperamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Loperamide Suppliers

Canada 1 China 39 India 4 United Kingdom 1 United States 9 Global 54

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18043
Advantage: 56

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9577
Advantage: 60

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57401
Advantage: 58

Hefei Molake Biotechnology Co., Ltd.

Tel: 0551-66336380 18956014586
Fax: 055166336380
Email: 983438788@qq.com
Country: China
ProdList: 2123
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7773
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32079
Advantage: 58

106900-12-3, LoperamideRelated Search:

1-(4-CHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL (R)-1-(4-CHLOROPHENYL)-1-PROPANOL fenpipramide 4-(4-CHLOROPHENYL)PIPERIDINE Alverine Trimethylamine N-oxide 4-(4-Chlorophenyl)piperidin-4-ol (Diphenyl-3,3 propyl)-1 phenyl-4 piperidine chlorhydrate [French] Loperamide Trimethylamine N-oxide dihydrate 2,2-DIPHENYLPROPYLAMINE HYDROCHLORIDE TRIETHYLAMINE N-OXIDE DIPHENAMID DESMETHYL LOPERAMIDE Loperamide

loperamide oxide

R 58425

trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide

trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate

Loperamide EP Impurity F

4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide

LoperaMide-d6 N-Oxide

Loperamide impurity-F(EP)

trans-Loperamide N-Oxide

Loperamide Impurity 6（Loperamide EP Impurity F）

Loperamide oxide monohydrate CRS

1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, 1-oxide, trans-

Loperamide EP Impurity F/ Loperamide Related Compound F (Loperamide N-Oxide)

4-[TRANS-4-(4-CHLOROPHENYL)-4-HYDROXY-1- OXIDOPIPERIDIN-1-YL]-N,N-DIMETHYL-2,2- DIPHENYLBUTANAMIDE HYDROCHLORIDE

Loperamide N-oxideQ: What is Loperamide N-oxide Q: What is the CAS Number of Loperamide N-oxide Q: What is the storage condition of Loperamide N-oxide Q: What are the applications of Loperamide N-oxide

Loperamide Related Compound F ((1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbu (1370065)

Loperamide Hydrochloride Impurity F

Loperamide EP Impurity F HCl

Loperamide USP Related Compound F

Loperamide Hydrochloride EP Impurity F

Loperamide EP Impurity F (Loperamide USP Related Compound F, trans-Loperamide N-Oxide)

106900-12-3

C29H27D6ClN2O3

Amines

Drug Analogues

Heterocycles

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Metabolites & Impurities

Pharmaceuticals