5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
- Product Name
- 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
- CAS No.
- 56990-57-9
- Chemical Name
- 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
- Synonyms
- NSC 87877;NSC 87877(free acid);XGMFVZOKHBRUTL-QURGRASLSA-N;8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid;5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-;5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-;(7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid
- CBNumber
- CB41243817
- Molecular Formula
- C19H13N3O7S2
- Formula Weight
- 459.45
- MOL File
- 56990-57-9.mol
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Property
- storage temp.
- Store at +4°C
- solubility
- ≥45.9 mg/mL in DMSO; insoluble in EtOH; ≥16.6 mg/mL in H2O with ultrasonic
- form
- Powder
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 14908
- Product name
- NSC 87877
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $38
- Updated
- 2024/03/01
- Product number
- 14908
- Product name
- NSC 87877
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $79
- Updated
- 2024/03/01
- Product number
- 14908
- Product name
- NSC 87877
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- 14908
- Product name
- NSC 87877
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 2613
- Product name
- NSC87877
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $162
- Updated
- 2021/12/16
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Chemical Properties,Usage,Production
Uses
NSC 87877 is an inhibitor of SHP2 and SHP1 protein tyrosine phosphatases
Definition
ChEBI: 8-oxo-7-[(6-sulfo-2-naphthalenyl)hydrazinylidene]-5-quinolinesulfonic acid is a naphthalenesulfonic acid.
Biological Activity
Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC 50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μ M for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
storage
Store at +4°C
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Preparation Products And Raw materials
Raw materials
Preparation Products
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