ChemicalBook > CAS DataBase List > 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-

Product Name
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
CAS No.
56990-57-9
Chemical Name
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
Synonyms
NSC 87877;NSC 87877(free acid);XGMFVZOKHBRUTL-QURGRASLSA-N;8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid;5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-;8-Hydroxy-7-((6-sulfonaphthalen-2-yl)diazenyl)quinoline-5-sulfonic acid;5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-;(7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid
CBNumber
CB41243817
Molecular Formula
C19H13N3O7S2
Formula Weight
459.45
MOL File
56990-57-9.mol
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5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Property

storage temp. 
Store at +4°C
solubility 
≥45.9 mg/mL in DMSO; insoluble in EtOH; ≥16.6 mg/mL in H2O with ultrasonic
form 
Powder
color 
Light brown to black
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14908
Product name
NSC 87877
Purity
≥98%
Packaging
10mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
14908
Product name
NSC 87877
Purity
≥98%
Packaging
25mg
Price
$79
Updated
2024/03/01
Cayman Chemical
Product number
14908
Product name
NSC 87877
Purity
≥98%
Packaging
50mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
14908
Product name
NSC 87877
Purity
≥98%
Packaging
100mg
Price
$220
Updated
2024/03/01
Tocris
Product number
2613
Product name
NSC87877
Purity
≥98%(HPLC)
Packaging
50
Price
$162
Updated
2021/12/16
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5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Chemical Properties,Usage,Production

Uses

NSC 87877 is an inhibitor of SHP2 and SHP1 protein tyrosine phosphatases

Definition

ChEBI: 8-oxo-7-[(6-sulfo-2-naphthalenyl)hydrazinylidene]-5-quinolinesulfonic acid is a naphthalenesulfonic acid.

Biological Activity

Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC 50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μ M for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

storage

Store at +4°C

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Suppliers

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56990-57-9, 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-Related Search:

8-HYDROXY-7-(6-SULFO-2-NAPHTHYLAZO)-5-QUINOLINESULFONIC ACID DISODIUM SALT (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE 2-Amino-5-methylphenyl)phosphonic Acid SID 487795 NSC228155 3-((Furan-2-ylmethyl)imino]-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine Hydrobromide 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- quinoline-5-sulphonic acid 8-Hydroxyquinoline-5-sulfonic acid 8-HYDROXYQUINOLINE-5-SULFONIC ACID MONOHYDRATE

  • 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
  • 8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid
  • NSC 87877
  • XGMFVZOKHBRUTL-QURGRASLSA-N
  • 5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-
  • NSC 87877(free acid)
  • (7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid
  • 8-Hydroxy-7-((6-sulfonaphthalen-2-yl)diazenyl)quinoline-5-sulfonic acid
  • 56990-57-9
  • Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP).