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Butin

Product Name
Butin
CAS No.
492-14-8
Chemical Name
Butin
Synonyms
(-)-Butin;(-)-Butin, 10 mM in DMSO;(S)-7,3',4'-Trihydroxyflavanone;(2S)-7,3',4'-Trihydroxyflavanone;7, 3', 4'-trihydroxydihydroflavone;inhibit,Inhibitor,()Butin,( ) Butin;butin (7, 3′, 4′-trihydroxydihydroflavone);(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one;(2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (S)-
CBNumber
CB41246292
Molecular Formula
C15H12O5
Formula Weight
272.25
MOL File
492-14-8.mol
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Butin Property

Melting point:
224-226℃
Boiling point:
582.4±50.0 °C(Predicted)
Density 
1.485
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.69±0.40(Predicted)
color 
Yellow to brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB69735
Product name
Butin
Packaging
500ug
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB69735
Product name
Butin
Packaging
1mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB69735
Product name
Butin
Packaging
2mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
6416CA
Product name
Butin
Packaging
1mg
Price
$164
Updated
2021/12/16
ChemScene
Product number
CS-0032187
Product name
(-)-Butin
Packaging
5mg
Price
$480
Updated
2021/12/16
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Butin Chemical Properties,Usage,Production

Uses

(-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2].

Definition

ChEBI: Butin is a trihydroxyflavanone in which the three hydroxy substituents are located at positions 3', 4' and 7. It is found in Acacia mearnsii, Vernonia anthelmintica and Dalbergia odorifera and has a protective affect against oxidative stress-induced mitochondrial dysfunction. It has a role as an antioxidant, a protective agent and a metabolite. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones.

References

[1] Duan J, et al. Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway. Sci Rep. 2017 Jan 27;7:41491. DOI:10.1038/srep41491
[2] Li P, et al. Butin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage by Anti Inflammatory Pathway. Transl Neurosci. 2018 May 8;9:7-12. DOI:10.1515/tnsci-2018-0002

Butin Preparation Products And Raw materials

Raw materials

Preparation Products

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Butin Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from Butin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Butin 492-14-8
Price
US $1.00-25.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
600KG
Release date
2024-07-17
Career Henan Chemical Co
Product
Butin 492-14-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kgs
Release date
2020-01-10

492-14-8, ButinRelated Search:


  • (2S)-7,3',4'-Trihydroxyflavanone
  • (S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (S)-
  • butin (7, 3′, 4′-trihydroxydihydroflavone)
  • (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
  • (S)-7,3',4'-Trihydroxyflavanone
  • 7, 3', 4'-trihydroxydihydroflavone
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S)-
  • (-)-Butin
  • inhibit,Inhibitor,()Butin,( ) Butin
  • (-)-Butin, 10 mM in DMSO
  • 492-14-8