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BUTEIN

Product Name
BUTEIN
CAS No.
487-52-5
Chemical Name
BUTEIN
Synonyms
BUTANOL;2',3,4,4'-TETRAHYDROCHALCONE;(2E)-;BUTEIN;CS-5675;BUTEIN(P);CCG208298;BUTEIN(SH);Butein >AC 1NQY7L)
CBNumber
CB8136455
Molecular Formula
C15H12O5
Formula Weight
272.25
MOL File
487-52-5.mol
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BUTEIN Property

Melting point:
216°C
Boiling point:
560.9±50.0 °C(Predicted)
Density 
1.483±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >50 mg/mL
form 
solid
pka
7.44±0.35(Predicted)
color 
yellow
LogP
2.405 (est)
CAS DataBase Reference
487-52-5(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
72795
Product name
Butein
Purity
analytical standard
Packaging
10mg
Price
$259
Updated
2024/03/01
Sigma-Aldrich
Product number
203987
Product name
Butein - CAS 487-52-5 - Calbiochem
Purity
A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor.
Packaging
5MG
Price
$272
Updated
2022/05/15
TCI Chemical
Product number
B3803
Product name
Butein
Purity
>98.0%(HPLC)
Packaging
1g
Price
$304
Updated
2024/03/01
TCI Chemical
Product number
B3803
Product name
Butein
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$138
Updated
2024/03/01
Cayman Chemical
Product number
15371
Product name
Butein
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
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BUTEIN Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

BUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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BUTEIN Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
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View Lastest Price from BUTEIN manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Butein 487-52-5
Price
US $0.00/MG
Min. Order
20MG
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-07
Shanghai Standard Technology Co., Ltd.
Product
Butein 487-52-5
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-21
Career Henan Chemical Co
Product
Butein 487-52-5
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

487-52-5, BUTEINRelated Search:


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  • BUTEIN(P)
  • 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-
  • Butein 2',3,4,4'-Tetrahydroxychalcone
  • 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol
  • 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol
  • 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol
  • 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol
  • 2-[2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol
  • 2-[2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)vinyl]-5-methylquinolin-8-ol
  • BUTEIN
  • 2',4',3,4-TETRAHYDROXYCHALCONE
  • 2',3,4,4'-TETRAHYDROXYCHALCONE
  • 2',3,4,4'-TETRAHYDROCHALCONE
  • 3,4,2',4'-TETRAHYDROXYCHALCONE
  • 1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE
  • BUTANOL
  • 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one
  • 2',3,4,4'-Tetrahydroxy-trans-chalcone
  • Einecs 207-659-5
  • BUTEIN(SH)
  • BUTEIN WITH HPLC
  • (2E)-
  • Butein - CAS 487-52-5 - Calbiochem
  • Butein &gt
  • Butein Butein
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
  • AC 1NQY7L)
  • Butein (NSC-652892
  • CCG208298
  • CS-5675
  • PDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,inhibit,cell,SIRT1,Phosphodiesterase (PDE),ERK,PKB,Butein,AKT,HeLa,HER1,p38,HepG2
  • (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
  • 487-52-5
  • Receptor Tyrosine Kinase Inhibitors
  • Epidermal Growth Factor Receptor (EGFR) and Src
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Kinase/Phosphatase Biology
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals