ChemicalBook > CAS DataBase List > 4-Chloro-1-butanol

4-Chloro-1-butanol

Product Name
4-Chloro-1-butanol
CAS No.
928-51-8
Chemical Name
4-Chloro-1-butanol
Synonyms
4-chlorobutan-1-ol;4-CHLOROBUTANOL;oro-1-butanoL;4-Chlorolbutanol;4-Choro-1-bytanol;4-CHLOROBUTANOL-1;4-chloro-1-butano;4-Chlorbutan-1-ol;4-CHLORO-1-BUTANOL;4-ChIoro-1-butanoI
CBNumber
CB5100347
Molecular Formula
C4H9ClO
Formula Weight
108.57
MOL File
928-51-8.mol
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4-Chloro-1-butanol Property

Boiling point:
84-85 °C/16 mmHg (lit.)
Density 
1.088 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.453(lit.)
Flash point:
97 °F
storage temp. 
2-8°C
solubility 
Soluble in methanol, chloroform, and dimethyl sufoxide.
form 
Liquid
pka
15.01±0.10(Predicted)
color 
Clear colorless to light yellow
BRN 
1731408
InChIKey
HXHGULXINZUGJX-UHFFFAOYSA-N
CAS DataBase Reference
928-51-8(CAS DataBase Reference)
NIST Chemistry Reference
4-Chloro-1-butanol(928-51-8)
EPA Substance Registry System
1-Butanol, 4-chloro- (928-51-8)
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Safety

Hazard Codes 
Xn,C,F
Risk Statements 
10-22-36/37/38-20/21/22-34-40
Safety Statements 
23-24/25-36/37/39-26-16-36/37
RIDADR 
UN 2920 8/PG 2
WGK Germany 
3
RTECS 
EL1325000
Hazard Note 
Harmful
TSCA 
Yes
HazardClass 
3.2
PackingGroup 
III
HS Code 
29055910
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H290May be corrosive to metals

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
278823
Product name
4-Chloro-1-butanol
Purity
technical grade, ~85%
Packaging
50ml
Price
$120
Updated
2024/03/01
Sigma-Aldrich
Product number
278823
Product name
4-Chloro-1-butanol
Purity
technical grade, ~85%
Packaging
250ml
Price
$309.6
Updated
2024/03/01
TCI Chemical
Product number
C0144
Product name
4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran)
Purity
>85.0%(GC)
Packaging
25g
Price
$58
Updated
2024/03/01
TCI Chemical
Product number
C0144
Product name
4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran)
Purity
>85.0%(GC)
Packaging
500g
Price
$435
Updated
2024/03/01
Alfa Aesar
Product number
L04042
Product name
4-Chloro-1-butanol, tech. 85%
Packaging
50g
Price
$72.8
Updated
2024/03/01
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4-Chloro-1-butanol Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Tetramethylene chlorohydrin is used inorganic synthesis.

Uses

4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.

Uses

4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.

Definition

ChEBI: A primary alcohol that is butan-1-ol substituted by a chloro group at position 4.

General Description

4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.

Health Hazard

The toxicity of this compound is low. How ever, the acute toxic symptoms are those ofethylene and propylene chlorohydrins. Oralintake of this compound caused muscle con traction, gastrointestinal pain, ulceration, andliver injury in test animals.
LD50 value, oral (mice): 990 mg/kg
Tetramethylene chlorohydrin caused tumorsin lungs in test animals. Its carcinogenicity,however, is not yet fully established.

Fire Hazard

Flammable; flash point 36°C (97°F); vapor density 3.7 (air = 1); the vapor forms an explosive mixture with air, range is not reported. Fire-extinguishing agent: “alcohol” foam; a water spray may be used to cool fire-exposed containers and to flush any spill. It decomposes to HCl and tetrahydrofuran on heating.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES and ALCOHOLS.

Waste Disposal

Tetramethylene chlorohydrin is burned ina chemical incinerator equipped with anafterburner and scrubber.

4-Chloro-1-butanol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-1-butanol Suppliers

Shaanxi PharmaGHS Science Co., LTD
Tel
13279368192 13279368192
Email
pharmaghs@126.com
Country
China
ProdList
564
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Anqing PhiChem Corporation
Tel
0556-5209970
Fax
0556-5209971
Email
salesaq@phichem.com.cn
Country
China
ProdList
36
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
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View Lastest Price from 4-Chloro-1-butanol manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Chloro-1-butanol 928-51-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-28
Hebei Mojin Biotechnology Co., Ltd
Product
4-Chloro-1-butanol 928-51-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Hebei Guanlang Biotechnology Co,.LTD
Product
4-Chloro-1-butanol 928-51-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2023-06-29

928-51-8, 4-Chloro-1-butanolRelated Search:


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  • ClCH24OH
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