ChemicalBook > CAS DataBase List > 4-Chloro-1-butanol
4-Chloro-1-butanol
- Product Name
- 4-Chloro-1-butanol
- CAS No.
- 928-51-8
- Chemical Name
- 4-Chloro-1-butanol
- Synonyms
- 4-chlorobutan-1-ol;4-CHLOROBUTANOL;oro-1-butanoL;4-Chlorolbutanol;4-Choro-1-bytanol;4-CHLOROBUTANOL-1;4-chloro-1-butano;4-Chlorbutan-1-ol;4-CHLORO-1-BUTANOL;4-ChIoro-1-butanoI
- CBNumber
- CB5100347
- Molecular Formula
- C4H9ClO
- Formula Weight
- 108.57
- MOL File
- 928-51-8.mol
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4-Chloro-1-butanol Property
- Boiling point:
- 84-85 °C/16 mmHg (lit.)
- Density
- 1.088 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.453(lit.)
- Flash point:
- 97 °F
- storage temp.
- 2-8°C
- solubility
- Soluble in methanol, chloroform, and dimethyl sufoxide.
- form
- Liquid
- pka
- 15.01±0.10(Predicted)
- color
- Clear colorless to light yellow
- BRN
- 1731408
- InChIKey
- HXHGULXINZUGJX-UHFFFAOYSA-N
- CAS DataBase Reference
- 928-51-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Chloro-1-butanol(928-51-8)
- EPA Substance Registry System
- 1-Butanol, 4-chloro- (928-51-8)
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Safety
- Hazard Codes
- Xn,C,F
- Risk Statements
- 10-22-36/37/38-20/21/22-34-40
- Safety Statements
- 23-24/25-36/37/39-26-16-36/37
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 3
- RTECS
- EL1325000
- Hazard Note
- Harmful
- TSCA
- Yes
- HazardClass
- 3.2
- PackingGroup
- III
- HS Code
- 29055910
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H290May be corrosive to metals
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 278823
- Product name
- 4-Chloro-1-butanol
- Purity
- technical grade, ~85%
- Packaging
- 50ml
- Price
- $120
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 278823
- Product name
- 4-Chloro-1-butanol
- Purity
- technical grade, ~85%
- Packaging
- 250ml
- Price
- $309.6
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C0144
- Product name
- 4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran)
- Purity
- >85.0%(GC)
- Packaging
- 25g
- Price
- $58
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C0144
- Product name
- 4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran)
- Purity
- >85.0%(GC)
- Packaging
- 500g
- Price
- $435
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L04042
- Product name
- 4-Chloro-1-butanol, tech. 85%
- Packaging
- 50g
- Price
- $72.8
- Updated
- 2024/03/01
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4-Chloro-1-butanol Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
Tetramethylene chlorohydrin is used inorganic synthesis.
Uses
4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
Uses
4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
Definition
ChEBI: A primary alcohol that is butan-1-ol substituted by a chloro group at position 4.
General Description
4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.
Health Hazard
The toxicity of this compound is low. How ever, the acute toxic symptoms are those ofethylene and propylene chlorohydrins. Oralintake of this compound caused muscle con traction, gastrointestinal pain, ulceration, andliver injury in test animals.
LD50 value, oral (mice): 990 mg/kg
Tetramethylene chlorohydrin caused tumorsin lungs in test animals. Its carcinogenicity,however, is not yet fully established.
Fire Hazard
Flammable; flash point 36°C (97°F); vapor density 3.7 (air = 1); the vapor forms an explosive mixture with air, range is not reported. Fire-extinguishing agent: “alcohol” foam; a water spray may be used to cool fire-exposed containers and to flush any spill. It decomposes to HCl and tetrahydrofuran on heating.
Safety Profile
Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES and ALCOHOLS.
Waste Disposal
Tetramethylene chlorohydrin is burned ina chemical incinerator equipped with anafterburner and scrubber.
4-Chloro-1-butanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-1-butanol manufacturers
Hebei Yanxi Chemical Co., Ltd.
- Product
- 4-Chloro-1-butanol 928-51-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-28
Hebei Weibang Biotechnology Co., Ltd
- Product
- 4-Chloro-1-butanol 928-51-8
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
Hebei Chuanghai Biotechnology Co,.LTD
- Product
- 4-Chloro-1-butanol 928-51-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99.%
- Supply Ability
- 10 ton
- Release date
- 2024-08-21
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