4-Amino-1-butanol
- Product Name
- 4-Amino-1-butanol
- CAS No.
- 13325-10-5
- Chemical Name
- 4-Amino-1-butanol
- Synonyms
- 4-aminobutan-1-ol;BUTANOLAMINE;4-AMINOBUTANOL;SKL271;N-ABU(4)-OL;H-ABUT(4)-OL;NH2-(CH2)4-OH;4-Aminobutanol-1;2-AcetyLhiophene;4-AMINO-1-BUTANOL
- CBNumber
- CB7853047
- Molecular Formula
- C4H11NO
- Formula Weight
- 89.14
- MOL File
- 13325-10-5.mol
4-Amino-1-butanol Property
- Melting point:
- 16-18 °C (lit.)
- Boiling point:
- 206 °C (lit.)
- Density
- 0.967 g/mL at 25 °C (lit.)
- refractive index
- n20/D ~1.462(lit.)
- Flash point:
- 226 °F
- storage temp.
- Store below +30°C.
- solubility
- Acetonitrile (Slightly), Chloroform (Sparingly), Methanol (Slightly)
- form
- Liquid
- pka
- 15.10±0.10(Predicted)
- color
- Clear colorless to slightly yellow
- Water Solubility
- MISCIBLE
- Sensitive
- Air Sensitive & Hygroscopic
- BRN
- 1731411
- Stability:
- Unstable in Aqueous Solution
- CAS DataBase Reference
- 13325-10-5(CAS DataBase Reference)
- NIST Chemistry Reference
- NH2(CH2)4OH(13325-10-5)
- EPA Substance Registry System
- 1-Butanol, 4-amino- (13325-10-5)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-22
- Safety Statements
- 26-36/37/39-45-25
- RIDADR
- UN 2735 8/PG 3
- WGK Germany
- 3
- F
- 34
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29221980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 178330
- Product name
- 4-Amino-1-butanol
- Purity
- 98%
- Packaging
- 1g
- Price
- $39.9
- Updated
- 2024/03/01
- Product number
- 178330
- Product name
- 4-Amino-1-butanol
- Purity
- 98%
- Packaging
- 5g
- Price
- $113
- Updated
- 2024/03/01
- Product number
- A1013
- Product name
- 4-Amino-1-butanol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $69
- Updated
- 2024/03/01
- Product number
- A1013
- Product name
- 4-Amino-1-butanol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $274
- Updated
- 2024/03/01
- Product number
- A12680
- Product name
- 4-Amino-1-butanol, 98%
- Packaging
- 1g
- Price
- $38.5
- Updated
- 2023/06/20
4-Amino-1-butanol Chemical Properties,Usage,Production
Description
4-Amino-1-butanol (4AB) is an important pharmaceutical intermediate compound and a precursor of biodegradable polymers for gene delivery. It can be used in organic synthesis and biological properties studies, among others. In addition, 4-Amino-1-butanol (4AB) has been shown to have a higher CO2 solubility than 2-amino-1-ethanol (MEA), which is potentially useful in solving problems related to flue gas purification[1-2].
Chemical Properties
Very light clear yellow liquid
Uses
4-Amino-1-butanol is a useful intermediate in a variety of organic synthesis. It is mainly used in personal-care products, preparation of water soluble cationic flocculants and ion exchange resins as well as in the preparation of beta-lactam antibiotics. It is used for the production of efficient anionic emulsifiers, nonionic polyethylene emulsions, water treatment, metal treatment and absorption of carbon dioxide gas. It is used as a pigment dispersion aid and curing agent in selected textile -resins.
Uses
4-Amino-1-butanol was used:
- As a linker in the synthesis of highly branched poly(β-amino esters)(HPAEs) for gene delivery.
- As a side chain to modulate antimicrobial and hemolytic activities of copolymers.
- In the total synthesis of (+)-fawcettimine,(+)-fawcettidine, and (?)-lycojapodine A.
Preparation
4-Amino-1-butanol (4AB) can be prepared by microbiological methods. we report for the first time the fermentative production of 4AB from glucose by metabolically engineered Corynebacterium glutamicum harboring a newly designed pathway comprising a putrescine (PUT) aminotransferase (encoded by ygjG) and an aldehyde dehydrogenase (encoded by yqhD) from Escherichia coli, which convert PUT to 4AB. Application of several metabolic engineering strategies such as fine-tuning the expression levels of ygjG and yqhD, eliminating competing pathways, and optimizing culture condition further improved 4AB production. Fed-batch culture of the final metabolically engineered C. glutamicum strain produced 24.7?g/L of 4AB[1].
References
[1] CINDY PRICILIA SURYA PRABOWO. Microbial production of 4-amino-1-butanol, a four-carbon amino alcohol[J]. Biotechnology and Bioengineering, 2020. DOI:10.1002/bit.27438.
[2] ZULKIFLI IDRIS . Equilibrium solubility of carbon dioxide in aqueous solutions of 3-amino-1-propanol, 4-amino-1-butanol and 5-amino-1-pentanol at low partial pressures[J]. Fluid Phase Equilibria, 2015. DOI:10.1016/j.fluid.2014.11.028.
4-Amino-1-butanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Amino-1-butanol manufacturers
- Product
- 4-Amino-1-butanol 13325-10-5
- Price
- US $980.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1-10mt
- Release date
- 2021-06-02
- Product
- 4-Amino-1-butanol 13325-10-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 10kg
- Purity
- 98%
- Supply Ability
- ton grade
- Release date
- 2023-05-10
- Product
- 4-Amino-1-butanol 13325-10-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-25