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1-Butanesulfonyl chloride

Product Name
1-Butanesulfonyl chloride
CAS No.
2386-60-9
Chemical Name
1-Butanesulfonyl chloride
Synonyms
Butane-1-sulfonyl chloride;1-ButanesuL;Butylsulfonyl;Butylsulfonylchloride;BUTANESULFONYLCHLORIDE;Butylsulfonyl chloride;Butanesulphonyl chloride;1-Butylsulfonyl chloride;N-BUTYLSULFONYL CHLORIDE;1-(Chlorosulphonyl)butane
CBNumber
CB1139240
Molecular Formula
C4H9ClO2S
Formula Weight
156.63
MOL File
2386-60-9.mol
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1-Butanesulfonyl chloride Property

Melting point:
-29°C
Boiling point:
80-81 °C/9 mmHg (lit.)
Density 
1.208 g/mL at 25 °C (lit.)
vapor pressure 
0.5 mm Hg ( 20 °C)
refractive index 
n20/D 1.454(lit.)
Flash point:
175 °F
form 
Liquid
color 
Clear colorless to light yellow or light orange
Water Solubility 
DECOMPOSES
Sensitive 
Moisture Sensitive
BRN 
1748742
InChIKey
WEDIIKBPDQQQJU-UHFFFAOYSA-N
CAS DataBase Reference
2386-60-9(CAS DataBase Reference)
NIST Chemistry Reference
1-Butanesulfonyl chloride(2386-60-9)
EPA Substance Registry System
1-Butanesulfonyl chloride (2386-60-9)
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Safety

Hazard Codes 
C
Risk Statements 
34-36/37
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
EK5950000
10-19-21
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29049090
Toxicity
mouse,LD50,intraperitoneal,> 100mg/kg (100mg/kg),Nature. Vol. 174, Pg. 737, 1954.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H335May cause respiratory irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P370+P378In case of fire: Use … for extinction.

P390Absorb spillage to prevent material damage.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B0866
Product name
1-Butanesulfonyl Chloride
Purity
>98.0%(T)
Packaging
25g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
B0866
Product name
1-Butanesulfonyl Chloride
Purity
>98.0%(T)
Packaging
500g
Price
$623
Updated
2024/03/01
Alfa Aesar
Product number
A18295
Product name
1-Butanesulfonyl chloride, 98%
Packaging
5g
Price
$26.65
Updated
2024/03/01
Alfa Aesar
Product number
A18295
Product name
1-Butanesulfonyl chloride, 98%
Packaging
100g
Price
$232.65
Updated
2024/03/01
TRC
Product number
B810658
Product name
1-Butanesulfonyl chloride
Packaging
1g
Price
$45
Updated
2021/12/16
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1-Butanesulfonyl chloride Chemical Properties,Usage,Production

Description

1-Butanesulfonyl chloride is an antimicrobial agent that inhibits the production of inflammatory substances. It has been shown to inhibit acetylcholinesterase activity and the growth of cancer cells in vitro. 1-Butanesulfonyl chloride is a cross-linking agent that can be used to produce amides, which are used as pharmaceutical preparations for treating inflammatory diseases.

Chemical Properties

clear colourless to light yellow liquid

Uses

1-Butanesulfonyl chloride has been used in the preparation of:

  • ethyl 2-(1-butanesulfonamido)pent-4-yn-l-oate
  • 1-butanesulfonamid-N,N′-1,2-ethanediylbis
  • 1-butanesulfonamide-N,N′-1,3-propanediylbis

Purification Methods

It has a pungent odour and is LACHRYMATORY. If IR shows OH bands, then dissolve in Et2O, wash with cold saturated aqueous NaHCO3 (care since CO2 will be generated) then H2O, dry it over solid Na2SO4, filter, evaporate and distil the residue twice. Characterise it by shaking a solution in Et2O or *C6H6 with aqueous NH3, collect the solid 1-butanesulfonamide with m 48o after recrystallisation from CHCl3, CCl4 or Et2O/pet ether. [Douglass & Johnson J Am Chem Soc 60 1488 1938, Lee & Dougherty J Org Chem 5 83 1940, Beilstein 4 IV 45.]

1-Butanesulfonyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Butanesulfonyl chloride Suppliers

Hangzhou Alltech Chemical Co., Ltd
Tel
0571-86739500
Fax
0571-86731857
Email
sales@alltechchem.com
Country
China
ProdList
42
Advantage
58
Shouguang Nuomeng Chemical Co Ltd.
Tel
536-5399456 13869682027
Fax
0536-5399456
Email
sales@nuomengchem.com
Country
China
ProdList
46
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
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View Lastest Price from 1-Butanesulfonyl chloride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-Butanesulfonyl chloride 2386-60-9
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-19
Shouguang Nuomeng Chemical Co Ltd.
Product
1-Butanesulfonyl chloride 2386-60-9
Price
US $130.00/KG
Min. Order
1KG
Purity
98% Min.
Supply Ability
Supply according to order quantity
Release date
2020-07-17
Hebei Mojin Biotechnology Co., Ltd
Product
1-Butanesulfonyl chloride 2386-60-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-24

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