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BUTEIN

Product Name
BUTEIN
CAS No.
487-52-5
Chemical Name
BUTEIN
Synonyms
BUTANOL;2',3,4,4'-TETRAHYDROCHALCONE;(2E)-;BUTEIN;CS-5675;BUTEIN(P);CCG208298;BUTEIN(SH);Butein >AC 1NQY7L)
CBNumber
CB8136455
Molecular Formula
C15H12O5
Formula Weight
272.25
MOL File
487-52-5.mol
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BUTEIN Property

Melting point:
216°C
Boiling point:
560.9±50.0 °C(Predicted)
Density 
1.483±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >50 mg/mL
form 
solid
pka
7.44±0.35(Predicted)
color 
yellow
LogP
2.405 (est)
CAS DataBase Reference
487-52-5(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
72795
Product name
Butein
Purity
analytical standard
Packaging
10mg
Price
$259
Updated
2024/03/01
Sigma-Aldrich
Product number
203987
Product name
Butein - CAS 487-52-5 - Calbiochem
Purity
A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor.
Packaging
5MG
Price
$272
Updated
2022/05/15
TCI Chemical
Product number
B3803
Product name
Butein
Purity
>98.0%(HPLC)
Packaging
1g
Price
$304
Updated
2024/03/01
TCI Chemical
Product number
B3803
Product name
Butein
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$138
Updated
2024/03/01
Cayman Chemical
Product number
15371
Product name
Butein
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
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BUTEIN Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

BUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BUTEIN manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Butein 487-52-5
Price
US $0.00/MG
Min. Order
20MG
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-07
Shanghai Standard Technology Co., Ltd.
Product
Butein 487-52-5
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-21
Career Henan Chemical Co
Product
Butein 487-52-5
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

487-52-5, BUTEINRelated Search:

NODAKENETIN viomycin Pterostilbene Butin 4-CHLORO-1-BUTANOL ACETATE 4-(tert-ButoxycarbonylaMino)-1-butanol 4-(2,2,6-TRIMETHYLCYCLOHEXYL)-2-BUTANOL 7,3',4'-TRIHYDROXYFLAVANONE 4-CHLORO-1-BUTANOL 4-(4-NITROPHENYL)-1-BUTANOL 4-METHYLMERCAPTO-2-AMINO-1-BUTANOL Chalcone 4-BROMO-3,3,4,4-TETRAFLUORO-1-BUTANOL 4-AMINO-2-BUTANOL 4-ETHYLAMINO-1-BUTANOL L-Methioninol 1,1,1,3,3,3-HEXAFLUORO-TERT-BUTANOL 4-AMINO-1-BUTANOL

  • (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxychalcone
  • BUTEIN(P)
  • 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-
  • Butein 2',3,4,4'-Tetrahydroxychalcone
  • 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol
  • 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol
  • 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol
  • 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol
  • 2-[2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol
  • 2-[2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol
  • 2-[2-(2-aminophenyl)vinyl]-5-methylquinolin-8-ol
  • BUTEIN
  • 2',4',3,4-TETRAHYDROXYCHALCONE
  • 2',3,4,4'-TETRAHYDROXYCHALCONE
  • 2',3,4,4'-TETRAHYDROCHALCONE
  • 3,4,2',4'-TETRAHYDROXYCHALCONE
  • 1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE
  • BUTANOL
  • 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one
  • 2',3,4,4'-Tetrahydroxy-trans-chalcone
  • Einecs 207-659-5
  • BUTEIN(SH)
  • BUTEIN WITH HPLC
  • (2E)-
  • Butein - CAS 487-52-5 - Calbiochem
  • Butein &gt
  • Butein Butein
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
  • AC 1NQY7L)
  • Butein (NSC-652892
  • CCG208298
  • CS-5675
  • PDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,inhibit,cell,SIRT1,Phosphodiesterase (PDE),ERK,PKB,Butein,AKT,HeLa,HER1,p38,HepG2
  • (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
  • 487-52-5
  • Receptor Tyrosine Kinase Inhibitors
  • Epidermal Growth Factor Receptor (EGFR) and Src
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Kinase/Phosphatase Biology
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals