4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
- Product Name
- 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
- CAS No.
- 17676-24-3
- Chemical Name
- 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
- Synonyms
- C10628;hinokiresinol;trans-Hikiresil;cis-Hinokiresinol;(-)-Hinokiresinol;trans-Hinokiresinol;4-[1-[(E)-4-Hydroxystyryl]allyl]phenol;4,4'-[(E)-3-Vinyl-1-propene-1,3-diyl]bis[phenol];4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol;Phenol,4,4'-[(1E,3S)-3-ethenyl-1-propene-1,3-diyl]bis-
- CBNumber
- CB41257863
- Molecular Formula
- C17H16O2
- Formula Weight
- 252.31
- MOL File
- 17676-24-3.mol
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Property
- Melting point:
- 69-71 °C(Solv: chloroform (67-66-3))
- Boiling point:
- 429.4±40.0 °C(Predicted)
- Density
- 1.163±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 9.88±0.26(Predicted)
- LogP
- 3.710 (est)
N-Bromosuccinimide Price
- Product number
- CFN99834
- Product name
- trans-Hinokiresinol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $463
- Updated
- 2021/12/16
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Chemical Properties,Usage,Production
Description
Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist, indicating that they are estrogen agonists. trans- and cis-Hinokiresinols have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation. 3. Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils. 4. Hinokiresinol has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction.
Definition
ChEBI: (-)-hinokiresinol is a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene that has 1E,3S configuration. A natural product found in Chamaecyparis obtusa. It has a role as a metabolite. It is a norlignan and a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene.
target
Estrogen receptor | NOS | IL Receptor | TNF-α | Progestogen receptor