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5-Aminolevulinic acid hexyl ester hydrochloride

Product Name
5-Aminolevulinic acid hexyl ester hydrochloride
CAS No.
140898-91-5
Chemical Name
5-Aminolevulinic acid hexyl ester hydrochloride
Synonyms
Hexvix;P 1206;Hexaminolevulinate HCl;ALA HEXYL ESTER HYDROCHLORIDE;AMINOLEVULINC ACID HEXYL ESTER;Hexaminolevulite hydrochloride;5-ALA hexyl ester hydrochloride;HexaMinolevulinate hydrochloride;Hexyl 5-aMinolevulinate hydrochloride;N-HEXYL 5-AMINOLEVULINATE HYDROCHLORIDE
CBNumber
CB4128630
Molecular Formula
C11H22ClNO3
Formula Weight
251.75
MOL File
140898-91-5.mol
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5-Aminolevulinic acid hexyl ester hydrochloride Property

Melting point:
94°
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO:41.0(Max Conc. mg/mL);162.86(Max Conc. mM)
form 
A solid
color 
White to off-white
Appearance
Solid Powder
Water Solubility 
H2O: 20mg/mL, clear
Sensitive 
Light Sensitive/Hygroscopic
InChI
InChI=1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
InChIKey
LZYXPFZBAZTOCH-UHFFFAOYSA-N
SMILES
C(=O)(OCCCCCC)CCC(=O)CN.Cl
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Safety

Hazard Codes 
Xi
HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1637
Product name
Hexaminolevulinate hydrochloride
Purity
≥98% (HPLC)
Packaging
10 mg
Price
$77.7
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1637
Product name
Hexaminolevulinate hydrochloride
Purity
≥98% (HPLC)
Packaging
50 mg
Price
$424.65
Updated
2025/07/31
Cayman Chemical
Product number
23949
Product name
Hexaminolevulinate (hydrochloride)
Purity
≥95%
Packaging
250mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23949
Product name
Hexaminolevulinate (hydrochloride)
Purity
≥95%
Packaging
500mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
23949
Product name
Hexaminolevulinate (hydrochloride)
Purity
≥95%
Packaging
1g
Price
$91
Updated
2023/06/20
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5-Aminolevulinic acid hexyl ester hydrochloride Chemical Properties,Usage,Production

Description

Hexaminolevulinate is a lipophilic, hexyl ester prodrug form of 5-aminolevulinic acid. It produces equivalent protoporphyrin IX (PpIX) induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS).

Uses

Diagnostic agent for the diagnosis of bladder cancer.

Uses

5-Aminolevulinic Acid Hexyl Ester Hydrochloride is used in treating domestic animal cancers through programmed cancer cell death and apoptosis-stimulating proteins.

Biological Activity

Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

5-Aminolevulinic acid hexyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Aminolevulinic acid hexyl ester hydrochloride Suppliers

BIOSYNTH AG
Tel
--
Fax
--
Email
welcome@biosynth.ch
Country
Switzerland
ProdList
1308
Advantage
60
Biosynth AG
Tel
--
Fax
--
Email
welcome@biosynth.ch
Country
Switzerland
ProdList
3324
Advantage
72
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View Lastest Price from 5-Aminolevulinic acid hexyl ester hydrochloride manufacturers

Career Henan Chemical Co
Product
5-Aminolevulinic acid hexyl ester hydrochloride 140898-91-5
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

140898-91-5, 5-Aminolevulinic acid hexyl ester hydrochlorideRelated Search:


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  • 140898-91-5
  • C11H21NO3ClH
  • C11H21NO3HCl
  • C11H22NO3Cl
  • Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives