ChemicalBook > CAS DataBase List > 2-Iodophenylacetic acid

2-Iodophenylacetic acid

Product Name
2-Iodophenylacetic acid
CAS No.
18698-96-9
Chemical Name
2-Iodophenylacetic acid
Synonyms
RARECHEM AL BO 1302;2-IODOPHENYLACETIC ACID;O-IODOPHENYLACETIC ACID;2-IodophenylaceticAcid>2-Iodo-benzeneacetic acid;2-(2-iodophenyl)aceticaci;BENZENEACETIC ACID, 2-IODO-;2-(2-IODOPHENYL)ACETIC ACID;2-Iodophenylacetic acid 97%;2-IODOPHENYLACETIC ACID, 97+%
CBNumber
CB4131159
Molecular Formula
C8H7IO2
Formula Weight
262.04
MOL File
18698-96-9.mol
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2-Iodophenylacetic acid Property

Melting point:
116-119 °C (lit.)
Boiling point:
344.5±17.0 °C(Predicted)
Density 
1.885±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Powder
pka
pK1:4.038 (25°C)
color 
Cream
Sensitive 
Light Sensitive
BRN 
2086800
CAS DataBase Reference
18698-96-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37
WGK Germany 
3
Hazard Note 
Irritant/Light Sensitive
HazardClass 
IRRITANT, LIGHT SENSITIVE
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
531472
Product name
2-Iodophenylacetic acid
Purity
97%
Packaging
5g
Price
$41.6
Updated
2024/03/01
Sigma-Aldrich
Product number
531472
Product name
2-Iodophenylacetic acid
Purity
97%
Packaging
25g
Price
$44.4
Updated
2024/03/01
TCI Chemical
Product number
I0723
Product name
2-Iodophenylacetic Acid
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$53
Updated
2024/03/01
TCI Chemical
Product number
I0723
Product name
2-Iodophenylacetic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$175
Updated
2024/03/01
Alfa Aesar
Product number
L15116
Product name
2-Iodophenylacetic acid, 98+%
Packaging
5g
Price
$57.65
Updated
2024/03/01
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2-Iodophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

Cream powder

Uses

2-Iodophenylacetic acid is a synthetic intermediate that is widely used in the chemical, pharmaceutical and cosmetic industries. 2-Iodophenylacetic acid is also used as a reagent to synthesize Cepharanone B, a natural and potentially antineoplastic aristolactam that is found in Piper longum (a medicinal plant native to India).

Application

2-Iodophenylacetic acid may be used in the preparation of:
2-iodophenylacetyl chloride
3,4-dimethoxyphenyl 2-iodophenylacetate
N-{2-[2-(2-iodophenyl)-acetylamino]-ethyl}-2-(3,4- dichlorophenyl)-acetamide

Preparation

synthesis of 2-Iodophenylacetic acid: The anthranilic acid solution was acidified with sulfuric acid to pH = 1 followed by a diazotization reaction. The diazonium was added dropwise to the potassium iodide-sulfuric acid solution (3.5 g KI, 1.0 mL concentrated H2SO4, 5 mL water) preheated to 60-70 °C, stirred for 30 min, placed overnight, and filtered to obtain the product. Recrystallization with 50% ethanol aqueous solution gave 3.83 g of 2-iodophenylacetic acid, the yield was 73% (calculated as o-nitrophenylacetic acid), and the melting point was 113-115 °C (117 °C reported in the literature).

General Description

2-Iodophenylacetic acid is a substituted acetic acid that can be prepared from 2-iodobenzyl cyanide. It undergoes palladium-catalyzed reaction with allenes to form 1,3-butadienes. 2-Iodophenylacetic acid also undergoes photolysis in carbon tetrachloride to form the corresponding chloro compound.

2-Iodophenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Iodophenylacetic acid Suppliers

INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
Rare Chemicals GmbH
Tel
--
Fax
--
Email
sales@rarechem.de
Country
Germany
ProdList
6297
Advantage
38
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 2-Iodophenylacetic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-Iodophenylacetic acid 18698-96-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-04-28
Henan Fengda Chemical Co., Ltd
Product
2-Iodophenylacetic acid 18698-96-9
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24
Shanghai Xinchem Co., Ltd.
Product
2-Iodophenylacetic acid 18698-96-9
Price
US $0.00-0.00/drums
Min. Order
1drums
Purity
99%min.
Supply Ability
10tons
Release date
2023-10-22

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