ChemicalBook > CAS DataBase List > Zearalenone

Zearalenone

Product Name
Zearalenone
CAS No.
17924-92-4
Chemical Name
Zearalenone
Synonyms
ZEN;ZON;(s)-zearalenone;RAL;(-)-Zearalenone;[S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione;ZENONE;toxinf2;f-2toxin;(3S,11E)-
CBNumber
CB4131407
Molecular Formula
C18H22O5
Formula Weight
318.36
MOL File
17924-92-4.mol
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Zearalenone Property

Melting point:
164-165°C
alpha 
25546 -170.5° (c = 1.0 in CH3OH)
Boiling point:
377.53°C (rough estimate)
Density 
1.1270 (rough estimate)
refractive index 
1.6120 (estimate)
Flash point:
6 °C
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml; Ethanol: 20 mg/ml
pka
7.58±0.40(Predicted)
form 
Solid
color 
Off-white
Merck 
13,10169
BRN 
1350216
InChIKey
MBMQEIFVQACCCH-QBODLPLBSA-N
LogP
3.830 (est)
CAS DataBase Reference
17924-92-4(CAS DataBase Reference)
EPA Substance Registry System
Zearalenone (17924-92-4)
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Safety

Hazard Codes 
C,Xn,F
Risk Statements 
34-62-63-36-20/21/22-11
Safety Statements 
26-36/37/39-45-36-16-36/37
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
DM2550000
F 
10
HS Code 
29322090
Hazardous Substances Data
17924-92-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CRM46916
Product name
Zearalenone solution
Purity
certified reference material, 50?μg/mL in acetonitrile, ampule of 1?mL
Packaging
1mL
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
34126
Product name
Zearalenone solution
Purity
100 μg/mL in acetonitrile, analytical standard
Packaging
2ml
Price
$488
Updated
2024/03/01
Sigma-Aldrich
Product number
32939
Product name
Zearalenone
Purity
reference material
Packaging
5mg
Price
$689
Updated
2022/05/15
Cayman Chemical
Product number
11353
Product name
Zearalenone
Purity
≥98%
Packaging
5mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
11353
Product name
Zearalenone
Purity
≥98%
Packaging
10mg
Price
$73
Updated
2024/03/01
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Zearalenone Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Zearalenone is a resorcylic acid lactone produced by a number of Fusarium sp.. Zearalenone acts as a non-steroidal estrogen, binding to estrogen receptor and is uterotropic. Zearalenone induces reproductive problems in animals and, in some animal models, is thought to be a primary initiator of hepatic tumours. In vivo, zearalenone undergoes metabolic reduction to the more estrogenic zearalenol. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenone and is regarded as an important food quality issue for both humans and animal health.

Uses

A phytoestrogenic mycotoxin and ER activator

Uses

Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylic acid lactones

Definition

ChEBI: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.

General Description

White microcrystals or white powder.

Air & Water Reactions

Zearalenone may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

Zearalenone is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Zearalenone may be incompatible with alkalis.

Fire Hazard

Flash point data for Zearalenone are not available. Zearalenone is probably combustible.

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.

Metabolic pathway

When zearalenone is subjected to microbial transformation by a fungus, Gliocladium roseum, it is converted to a 1 : 1 mixture of 1-(3,5-dihydroxyphenyl)- 10 0 -hydroxy-1-undecen-6'-one and 1-(3,5- dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one.

storage

-20°C

Zearalenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Zearalenone Suppliers

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View Lastest Price from Zearalenone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Zearalenone 17924-92-4
Price
US $0.00-0.00/KG
Min. Order
100g
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-19
Career Henan Chemical Co
Product
Zearalenone 17924-92-4
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

17924-92-4, ZearalenoneRelated Search:

Thiophanate-methyl Androstenedione Clethodim Bensulfuron methyl Methyl salicylate 2-Cyclohexen-1-one Trenbolone Zeranol Methylparaben Kresoxim-methyl Methyl acetate Quinocetone METSULFURON METHYL Zein trans-Zeatin TRANS-ZEATIN RIBOSIDE ZEARALANONE CORN OIL

  • (E)-(S)-2,4-DIHYDROXY-7-METHYL-7,8,9,10,13,14-HEXAHYDRO-12H-6-OXA-BENZOCYCLOTETRADECENE-5,11-DIONE
  • ZON
  • ZENONE
  • ZEARALENONE
  • (10s)-zearalenone
  • (e)--methyl-7-oxo
  • (s-(e))-xy-3-methyl
  • (s)-zearalenone
  • 3,4,5,6,9,10-HEXAHYDRO-14,16-DIHYDROXY-3-METHYL-1H-2-BENZOXACYCLOTETRADECIN-1,7(8H)-DIONE
  • MYCOTOXIN F2
  • Zearalenone, froM Giberella zeae
  • (2E,11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraene-7,13-dione
  • Zearalenone, >=98%
  • Zearalenone [S-(E)]-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
  • ZEARALENONE, FUNGAL MYCOTOXIN
  • 14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
  • Zearalenone( F-2 toxin)
  • Zearalenone, 98%, from Giberella zeae
  • [s-(e)]-xy-3-methyl
  • 16-dihydroxy-3-methyl-7-oxo-1trans-benzoxacyclotetradec-11-en-1-on
  • 1h-2-benzoxacyclotetradecin-1,7(8h)-dione,3,4,5,6,9,10-hexahydro-14,16-dihydro
  • 1h-2-benzoxacyclotetradecin-1-one,3,4,5,6,7,8,9,10-octahydro-14,16-dihydroxy-3
  • 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1h-2-benzoxacyclotetradecin-1,
  • 6-(10-hydroxy-6-oxo-1-undecenyl)-,mu-lactone,trans-resorcylicaci
  • 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylicacidlactone
  • 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylicacid-n-lactone
  • 7(8h)-dione
  • compoundf-2
  • f-2toxin
  • fusariumtoxin
  • nci-c50226
  • toxinf2
  • trans-zearalenone
  • [S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
  • zearalenone solution
  • 3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1,7(8H)-dione, FES, Compound F-2, Toxin F2
  • (3S,11E)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2 -benzoxacyclotetradecin-1,7(8H)-dione
  • rac Zearalenone-d6
  • 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (3S,11E)-
  • Zearalenone solution,ZON
  • (3S,11E)-
  • (S,E)-14,16-dihydroxy-3-Methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
  • Mycotoxin F2, Toxin F2
  • ZEN
  • Zearalenone in corn, mid level
  • Zearalenone Standard
  • Zearalenone in corn, high level
  • Zearalenone in corn, low level
  • Zearalenone Solution (100μg/ml Acetonitrile Solution)
  • RAL
  • Zearalenone Ready Made Solution
  • Zearalenone 100ug/ml in ACN
  • Zearalenone Solution in Methanol, 100μg/mL
  • Zearalenone Solution in Acetonitrile, 100μg/mL
  • (-)-Zearalenone
  • Zearalenone USP/EP/BP
  • earalenone
  • Zearalenone (Mycotoxin F2