ChemicalBook > CAS DataBase List > licarin B

licarin B

Product Name: licarin B
CAS No.: 51020-87-2
Chemical Name: licarin B
Synonyms: licarin B;Licarine B;(-)-Licarin B;Licarin B, 10 mM in DMSO;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI);5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
CBNumber: CB41314632
Molecular Formula: C20H20O4
Formula Weight: 324.37
MOL File: 51020-87-2.mol

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licarin B Property

Boiling point:: 428.5±45.0 °C(Predicted)
Density: 1.201±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
color: White
InChI: InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m1/s1
InChIKey: DMMQXURQRMNSBM-YZAYTREXSA-N
SMILES: O1C2=CC=C([C@H]3[C@H](C)C4=CC(/C=C/C)=CC(OC)=C4O3)C=C2OC1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: N1572
Product name: (-)-LicarinB
Packaging: 20mg
Price: $250
Updated: 2021/12/16

AK Scientific

Product number: Y1205
Product name: licarinB
Packaging: 25mg
Price: $336
Updated: 2021/12/16

AvaChem

Product number: 3586
Product name: (-)-Licarin B
Packaging: 5mg
Price: $89
Updated: 2021/12/16

AvaChem

Product number: 3586
Product name: (-)-Licarin B
Packaging: 20mg
Price: $189
Updated: 2021/12/16

Crysdot

Product number: CD11113736
Product name: LicarinB
Purity: 97%
Packaging: 25mg
Price: $238
Updated: 2021/12/16

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licarin B Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.

Uses

Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.

Biological Activity

Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.

in vitro

Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.

Cell Viability Assay < /p>

Cell Line:	3T3-L1 cell.
Concentration:	1-500 μM.
Incubation Time:	48 h.
Result:	Did not cause significant cell death up to 500 μM concentration.

Cell Viability Assay

td>

Cell Line:	3T3-L1 cell.
Concentration:	5 μM, 10 μM, 15 μM.
Incubation Time:	8 days (replaced every 2 days).	8 days (replaced every 2 days).
Result:	LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.

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target

PPAR | GLUT | PI3K | Akt | IRS-1

licarin B Preparation Products And Raw materials

Raw materials

Preparation Products

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licarin B Suppliers

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View Lastest Price from licarin B manufacturers

Shanghai Standard Technology Co., Ltd.

Product: (-)-Licarin B 51020-87-2
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 100 g
Release date: 2020-08-12

Career Henan Chemical Co

Product: licarin B 51020-87-2
Price: US $1.00/kg
Min. Order: 1 mg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

51020-87-2, licarin BRelated Search:

beta-Eudesmol MONOMYRISTIN MOSLOFLAVONE ALPHA-CARYOPHYLLENE Myristic acid 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol Eugenol alpha-Cyperone Hydroxyecdysone alpha-Terpineol Myristicin Artemether hydroxygenkwanin 4-[(2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-2-methoxyphenol TRIMYRISTIN

1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI)

licarin B

5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole

5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole

5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole

Licarine B

1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-

(-)-Licarin B

5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole

Licarin B, 10 mM in DMSO

51020-87-2

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

reagent

standard substance