ChemicalBook > CAS DataBase List > apomine
apomine
- Product Name
- apomine
- CAS No.
- 126411-13-0
- Chemical Name
- apomine
- Synonyms
- F-99085;apomine;SR-9223i;SR-45023A;APB-231-A2;APB-231-A-2;Apomine, 10 mM in DMSO;Phosphonic acid, P,P'-[2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethylidene]bis-, P,P,P',P'-tetrakis(1-methylethyl) ester
- CBNumber
- CB41322363
- Molecular Formula
- C28H52O7P2
- Formula Weight
- 562.66
- MOL File
- 126411-13-0.mol
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apomine Property
- Melting point:
- 102-104 °C
- Boiling point:
- 584.5±50.0 °C(Predicted)
- Density
- 1.066±0.06 g/cm3(Predicted)
- pka
- 12.02±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0009218
- Product name
- SR-45023A
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.3
- Updated
- 2021/12/16
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apomine Chemical Properties,Usage,Production
Uses
Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. Apomine can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. In addition, Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer[1].
References
[1] Kuehl PJ, et al. Preformulation, formulation, and in vivo efficacy of topically applied apomine. Int J Pharm. 2009;382(1-2):104-110. DOI:10.1016/j.ijpharm.2009.08.016
apomine Preparation Products And Raw materials
Raw materials
Preparation Products
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apomine Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
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