2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose

Product Name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose
CAS No.: 97614-43-2
Chemical Name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose
Synonyms: D-Arabinofuranose;1,3,5-TRI-O-BENZOYL-2-DEOXY-2-FLUORO-A-D-ARABINOFURANOSE;2-DEOXY-2-FLUORO-1,3,5-TRI-O-BENZOYL-ALPHA-D-ARABINOFURANOSE;FLuorosugar;2-fluoro-2-deoxy-1;2-Deoxy-2-fluoro-1,3;InterMediate of Clofarabine;2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α2-deoxy-2-fluoro-tribenzoyl - α - d-alarbulose;2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofur
CBNumber: CB4137232
Molecular Formula: C26H21FO7
Formula Weight: 464.44
MOL File: 97614-43-2.mol

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2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose Property

Melting point:: 74-77°C
Boiling point:: 584.1±50.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in chloroform or dichloromethane
form: Powder
color: White to Off-white
InChIKey: JOAHVPNLVYCSAN-PPTKZWKYSA-N
SMILES: [C@H]1(OC(=O)C2=CC=CC=C2)[C@H](F)[C@@H](OC(=O)C2C=CC=CC=2)O[C@@H]1COC(=O)C1C=CC=CC=1 |&1:0,10,12,23,r|
CAS DataBase Reference: 97614-43-2(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D4594
Product name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-alpha-D-arabinofuranose
Purity: >98.0%(GC)
Packaging: 1g
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: D4594
Product name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-alpha-D-arabinofuranose
Purity: >98.0%(GC)
Packaging: 5g
Price: $124
Updated: 2025/07/31

TRC

Product number: D235500
Product name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose
Packaging: 10g
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 008101
Product name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose|
Packaging: 250mg
Price: $446
Updated: 2021/12/16

TRC

Product number: D235500
Product name: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose
Packaging: 25g
Price: $120
Updated: 2021/12/16

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2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

It is a pharmaceutical intermediate and is used as an OLED materials.

Uses

Clofarabine intermediate.

Synthesis

97614-42-1

97614-43-2

Synthesis of Compound VIII: Compound VII (2.2 mmol) was dissolved in ethyl acetate (54 mL) and triethylamine (Et3N) was added. Hydrogen trifluoride (3HF, 2.08 mL, 0.013 mmol) was added slowly under stirring. The reaction mixture was heated to 60°C with continuous stirring for 3 hours, followed by warming to 70°C with continued stirring for 1.5 hours. Upon completion of the reaction, the reaction was quenched by the addition of ice brine (10 mL) and extracted with dichloromethane. The organic phases were combined and washed sequentially with brine, water and saturated sodium bicarbonate solution and dried over anhydrous sodium sulfate for 4 hours. The solvent was removed by concentration under reduced pressure to give a dark yellow syrupy crude product. Purification by silica gel column chromatography (5 cm × 5 cm, eluted with dichloromethane) gave a light yellow syrupy product in 86.8% yield. Finally, the crude product was recrystallized in 95% ethanol to give the white crystalline compound VIII in 66.4% yield.1H NMR (CDCl3) δ ppm: 7.31-8.10 (m, 15H, OBz), 6.71 (d, J = 9.0 Hz, 1H, H-1), 5.68 (dd, J = 19.44 Hz, 1H, H-3). 5.32 (d, J = 48.2 Hz, 1H, H-2), 4.65-4.77 (m, 3H, H-4, H-5). Melting point: 80-82°C.

References

[1] Patent: EP2177527, 2010, A1. Location in patent: Page/Page column 11-12
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 1999, vol. 42, # SUPPL. 1, p. S638-S640
[3] Tetrahedron Letters, 1996, vol. 37, # 1, p. 17 - 20

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose Suppliers

Americas 1 Austria 1 Canada 4 China 278 Europe 2 Germany 5 India 7 Japan 1 Switzerland 3 United Kingdom 10 United States 37 Global 349

TCI Chemicals (India) Pvt. Ltd.

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Reax Chemicals

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A.J Chemicals

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View Lastest Price from 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose 97614-43-2
Price: US $0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-17

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose 97614-43-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

Zhuozhou Wenxi import and Export Co., Ltd

Product: Fluorosugar 97614-43-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

97614-43-2, 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranoseRelated Search:

Triethyl phosphonoacetate Benzoyl peroxide Benzoyl chloride Diethylstilbestrol Methyl-2-deoxy-D-erythropentofuranoside dibenzoate Methyl-2-deoxy-alpha-D-ribofuranoside 2-Deoxy-D-ribose 1,3,5-Tri-O-acetyl-2-deoxy-D-erythro-pentofuranose 1,3,5-Tri-O-acetyl-2-deoxy-alpha-D-erythro-pentofuranose Methyl-2-deoxy-D-ribofuranoside diacetate 2-DEOXY-2-FLUORO-1,3,5-TRI-O-BENZOYL-L-RIBOFURANOSE 1,3,5-Tri-O-benzoyl-D-ribofuranose Triphenylformazan D-RIBOFURANOSE, 2-DEOXY-2-FLUORO-1-ACETATE 3,5-DIBENZOATE 2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate METHYL-2-DEOXY-2-FLUORO-D-ARABINOFURANOSIDE 1-Acetyl-2-deoxy-3,5-di-O-benzoylribofuranose 2-FLUORO-2-DEOXY-1,3,5-TRI-O-ACETYL-A-D-ARABINOFURANOSEDISCONTINUED

1,3,5-TRI-O-BENZOYL-2-DEOXY-2-FLUORO-A-D-ARABINOFURANOSE

2-DEOXY-2-FLUORO-1,3,5-TRI-O-BENZOYL-A-D-ARABINOFURANOSE

2-DEOXY-2-FLUORO-1,3,5-TRI-O-BENZOYL-ALPHA-D-ARABINOFURANOSE

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-arabinofuranose

2-Deoxy-2-Fluoro-1,3,5-Tribenzoate-alpha-D- Arabinofuranose Min98% C3

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α- D-arabinof

InterMediate of Clofarabine

2-Fluoro-2deoxy-1,3,5-O-benzoyl-a-D-arabinofuranos

2-fluoro-2-deoxy-1,3,5-tri-O-benzoyl-*A-D-arabino

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-alpha- D-ribofuranose

FLuorosugar

Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-alpha-D-arabinofuranose

2-Fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-D-arabinofuranose

1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro -α-D-arabinose

2-Deoxy-2-fluoro-1,3

1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose ,98%

1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose

2-deoxy-2-fluoro-tribenzoate-a-D-Arabinofuranose

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranos

1,3,5-Tri-O-benzoyl-2'-deoxy-2'-fluoro-arabinoside

[3,5-BIS(BENZOYLOXY)-4-FLUOROOXOLAN-2-YL]METHYL BENZOATE

2-fluoro-2-deoxy-1

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-&alpha

[(2R,3R,4S,5R)-3,5-bis(benzoyloxy)-4-fluorooxolan-2-yl]methyl benzoate

α-D-Arabinofuranose, 2-deoxy-2-fluoro-, tribenzoate (9CI)

2-deoxy-2-fluoro-1,3,5-tri-O-benzoyl-1-α-D- arabinofuranose

2-deoxy-2-fluoro-1,3,5-tribenzoate-alpha-d-arabinofuranose

a-D-Arabinofuranose,2-deoxy-2-fluoro-, 1,3,5-tribenzoate

α-D-Arabinofuranose,2-deoxy-2-fluoro-,1,3,5-tribenzoate

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose (Decitabine)

1,3,5-tri-benzoyl-2-Deoxy-2-fluoro-α-D-arabinofunose

2-deoxy-2-fluoro-1,3,5-tri-o-benzoyl-d-ribofuranose

2-FLUORO-2DEOXY-1,3,5-O-BENZOYL-A-D-ARABINOFURANOSE

2-FLUORO-2-DEOXY-1,3,5-TRIBENZOYL-ALPHA-D-ARABINOFURANOSE

2-FLUORO-2-DEOXY-1,3,5-TRI-O-BENZOYL-ALPHA-D-ARABINOFURANOSE

a-D-Arabinofuranose, 2-deoxy-2-fluoro-, tribenzoate

alpha-D-Arabinofuranose-2-deoxy-2-fluoro-1,3,5-tribenzoate

2-Deoxy-2-Flouro-1,3,5-Tri-O-Benzoylalpha-D-Araninofuranose

2-Deoxy-2-fluoro-1,3,5-tri-O-Bza-D-ribofuranose

D-Arabinofuranose

2-FLUORO-2-DEOXY-1,3,5-TRI-O-BENZOYL-*A-D-ARABINOFUR

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose≥ 98% (HPLC)

α-D-Arabinofuranose, 2-deoxy-2-fluoro-, tribenzoate

2-deoxy-2-fluoro-tribenzoyl - α - d-alarbulose

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose &gt

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose

1,3,5-Tri-O-Benzoyl-2-Deoxy-2-Fluoro -α-D-Arabinose

2-deoxy-2-fluoro-1,3,5-tri-o-benzoyl-alpha-D-arabinofuranoseenzoyl-alpha-D-arabinofuranose

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose USP/EP/BP

2-Deoxy-2-fluoro-α-D-arabinofuranose 1,3,5-tribenzoate

2-Deoxy-2-Fluoro-1,3,5-Tribenzoate-α-D-Arabinofuranose

[(2R,3R,4S,5R)-3,5-dibenzoyloxy-4-fluorooxolan-2-yl]methyl benzoate

1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-alpha-D-arab

2- deoxy -2- fluoro -1,3,5- tribenzoyl -alpha-D- arabinofuranose

α-D-Arabinofuranose, 2-deoxy-2-fluoro-, 1,3,5-tribenzoate

2-deoxy-2-fluoro-1,3,5-tribenzoyl-alpha-D-arabofuranose (fluorose)

2-deoxy-2-fluoro-1,3,5-tribenzoyl-alpha D-arabifurose (fluorose)

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofur