4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE
- Product Name
- 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE
- CAS No.
- 220227-98-5
- Chemical Name
- 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE
- Synonyms
- 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE;Benzaldehyde, 4-hydroxy-3-(trifluoromethyl)-;4-Formyl-2-(trifluoromethyl)phenol, 5-Formyl-2-hydroxybenzotrifluoride
- CBNumber
- CB4138789
- Molecular Formula
- C8H5F3O2
- Formula Weight
- 190.12
- MOL File
- 220227-98-5.mol
4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE Property
- Melting point:
- 159-163°C
- Boiling point:
- 224.0±35.0 °C(Predicted)
- Density
- 1.429±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 5.79±0.43(Predicted)
- color
- Light brown
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 220227-98-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS013813
- Product name
- 4-hydroxy-3-(trifluoromethyl)benzaldehyde
- Purity
- AldrichCPR
- Packaging
- 250mg
- Price
- $66.1
- Updated
- 2025/07/31
- Product number
- H999900
- Product name
- 4-Hydroxy-3-(trifluoromethyl)benzaldehyde
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- H999900
- Product name
- 4-Hydroxy-3-(trifluoromethyl)benzaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- X2735
- Product name
- 4-Hydroxy-3-(trifluoromethyl)benzaldehyde
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 2815-3-13
- Product name
- 4-Hydroxy-3-(trifluoromethyl)benzaldehyde
- Packaging
- 1g
- Price
- $140
- Updated
- 2021/12/16
4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE Chemical Properties,Usage,Production
Synthesis
444-30-4
220227-98-5
Step 1: 2-Trifluoromethylphenol (5.0 g, 30.86 mmol) was dissolved in trifluoroacetic acid (50 mL) with hexamethylenetetetramine (8.64 g, 61.72 mmol) and the reaction was stirred at 65°C for 18 hours. After completion of the reaction, the reaction solution was concentrated and diluted with 2N aqueous hydrochloric acid. The acidic aqueous phase was extracted twice with ethyl acetate, and the organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated. The residue was purified by fast column chromatography (Biotage FLASH 40M, silica gel column, eluent: 20% ethyl acetate/hexane) to give 2.1 g of 4-hydroxy-3-(trifluoromethyl)benzaldehyde in 36% yield. Mass spectrum (electrospray ionization) m/z: 188.9; high resolution mass spectrum (calculated value C8H5F3O2, 190.0242; measured value [ESI, M+H]+, 191.0324).
References
[1] Patent: WO2005/37807, 2005, A1. Location in patent: Page/Page column 218-219
4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE manufacturers
- Product
- 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE 220227-98-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2025-03-10
- Product
- 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE 220227-98-5
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02