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YADANZIOLIDE-C

Product Name
YADANZIOLIDE-C
CAS No.
95258-12-1
Chemical Name
YADANZIOLIDE-C
Synonyms
YADANZIOLIDE-C;(+)-13,20-Epoxy-1α,11β,12α,14,15β-pentahydroxypicras-3-ene-2,16-dione;(+)-13,20-Epoxy-1α,11β,12α,14,15β-pentahydroxypicrasa-3-ene-2,16-dione;Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1α,11β,12α,15β)- (9CI)
CBNumber
CB41403505
Molecular Formula
C20H26O9
Formula Weight
410.42
MOL File
95258-12-1.mol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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YADANZIOLIDE-C Chemical Properties,Usage,Production

Uses

Yadanziolide C is a quassinoid with antiproliferative and differentiation-inducing properties in promyelocytic HL-60 cells[1].

References

[1] L Luyengi, et al. A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 1996 Sep;43(2):409-12. DOI:10.1016/0031-9422(96)00258-0
[2] E Mata-Greenwood, et al. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. Nat Prod. DOI:10.1021/np010212p

YADANZIOLIDE-C Preparation Products And Raw materials

Raw materials

Preparation Products

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