furo[3,2-b]pyridine
- Product Name
- furo[3,2-b]pyridine
- CAS No.
- 272-62-8
- Chemical Name
- furo[3,2-b]pyridine
- Synonyms
- 4-Azabenzo[b]furan;furo[3,2-b]pyridine;Furo[3,2-b]pyridine,98%;4-Azabenzo[b]furan, 4-Aza-1-benzofuran
- CBNumber
- CB41515864
- Molecular Formula
- C7H5NO
- Formula Weight
- 119.12
- MOL File
- 272-62-8.mol
furo[3,2-b]pyridine Property
- Boiling point:
- 79-80℃ (12 Torr)
- Density
- 1.2g/ml
- refractive index
- 1.5753 (19℃)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- liquid
- pka
- 4.22±0.30(Predicted)
- color
- Clear Colourless
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- F822570
- Product name
- Furo[3,2-b]pyridine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR17929
- Product name
- Furo[3,2-b]pyridine
- Packaging
- 250mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- 4H56-1-2M
- Product name
- Furo[3,2-b]pyridine
- Packaging
- 250mg
- Price
- $72
- Updated
- 2021/12/16
- Product number
- Y8522
- Product name
- Furo[3,2-b]pyridine
- Packaging
- 250mg
- Price
- $117
- Updated
- 2021/12/16
- Product number
- OR17929
- Product name
- Furo[3,2-b]pyridine
- Packaging
- 1g
- Price
- $163
- Updated
- 2021/12/16
furo[3,2-b]pyridine Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 23, p. 665, 1986 DOI: 10.1002/jhet.5570230305
Synthesis
92671-70-0
272-62-8
PdCl2(PPh3)2 (1.4 g, 2.0 mmol) and CuI (0.4 g, 2.1 mmol) were dissolved in a solvent mixture of triethylamine (TEA, 100 mL) and tetrahydrofuran (THF, 200 mL) under nitrogen atmosphere. Subsequently, a solution of 2-bromo-3-acetoxypyridine (13.1 g, 60.6 mmol) and trimethylsilylacetylene (TMS-acetylene, 7.0 g, 71 mmol) in THF (100 mL) was added one time to the above solution. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution (50 mL) and methanol (50 mL). The mixture was continued to be stirred at 80 °C for 2 hours. After cooling to room temperature, it was extracted with ether. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by column chromatography to afford furo[3,2-b]pyridine (1.54 g, 21% yield).1H NMR (CDCl3, 400 MHz) δ 8.55 (m, 1H), 7.84 (m, 1H), 7.75 (m, 1H), 7.72 (m, 1H), 6.99 (m, 1H).
References
[1] Patent: WO2005/51304, 2005, A2. Location in patent: Page/Page column 144
[2] Patent: WO2005/51304, 2005, A2. Location in patent: Page/Page column 144
furo[3,2-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
furo[3,2-b]pyridine Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
- --
- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74
View Lastest Price from furo[3,2-b]pyridine manufacturers
- Product
- 4-AZABENZO[B]FURAN 272-62-8
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50kg
- Release date
- 2025-06-24