ChemicalBook > CAS DataBase List > N-Fluorobenzenesulfonimide

N-Fluorobenzenesulfonimide

Product Name
N-Fluorobenzenesulfonimide
CAS No.
133745-75-2
Chemical Name
N-Fluorobenzenesulfonimide
Synonyms
NFSI;N-fluoro-N-(phenylsulfonyl)benzenesulfonamide;NFBS;N-FLUORODIBENZENESULFONIMIDE;N-Fluorobenzenesulfonmide;N-FLUOROBENZENESULFONAMIDE;N-(benzenesulfonyl)-N-fluorobenzenesulfonamide;N-FLUOROBIS(PHENYLSULFONYL)AMINE;N-FLUORODI(BENZENESULFONYL)AMINE;N-Fluorobenzenesulfonimide, N-Fluorodibenzenesulfonimide, NFSI
CBNumber
CB4156620
Molecular Formula
C12H10FNO4S2
Formula Weight
315.34
MOL File
133745-75-2.mol
More
Less

N-Fluorobenzenesulfonimide Property

Melting point:
114-116 °C
Boiling point:
471.4±28.0 °C(Predicted)
Density 
1.4466 (estimate)
Flash point:
110℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Very soluble in acetonitrile, dichloromethane or THF and less soluble in toluene.
form 
solid
pka
-32.45±0.70(Predicted)
color 
white
BRN 
5348902
InChIKey
RLKHFSNWQCZBDC-UHFFFAOYSA-N
CAS DataBase Reference
133745-75-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,O
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
F 
10
Hazard Note 
Oxidising Agent
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29242990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
392715
Product name
N-Fluorobenzenesulfonimide
Purity
97%
Packaging
5g
Price
$87.8
Updated
2024/03/01
Sigma-Aldrich
Product number
392715
Product name
N-Fluorobenzenesulfonimide
Purity
97%
Packaging
500g
Price
$532
Updated
2023/01/07
TCI Chemical
Product number
F0335
Product name
N-Fluorobenzenesulfonimide [Fluorinating Reagent]
Purity
>97.0%(T)
Packaging
5g
Price
$77
Updated
2024/03/01
TCI Chemical
Product number
F0335
Product name
N-Fluorobenzenesulfonimide [Fluorinating Reagent]
Purity
>97.0%(T)
Packaging
25g
Price
$267
Updated
2024/03/01
Alfa Aesar
Product number
L13955
Product name
N-Fluorobenzenesulfonimide, 97%
Packaging
1g
Price
$26.65
Updated
2024/03/01
More
Less

N-Fluorobenzenesulfonimide Chemical Properties,Usage,Production

Chemical Properties

Off-white to light brown crystalline powder

Uses

Versatile fluorinating reagent used in the fluorination of aryls, enolates, carbanions, organolithiums, etc.

Uses

N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates and carbanions in high yield. It is used for diastereoselective fluorination of Li enolates of chiral carboximides, for directed fluorination of ortho-lithiated aromatics and for a review of electrophilic N-F fluorinating agents. Asymmteric fluorinations is effected in the presence of a Pd-BINAP catalyst system at room temperature in an ionic liquid. It is a reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. It is also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.

Application

N-Fluorobenzenesulfonimide is a mild electrophilic fluorinating reagent, that can also be used as a strong oxidant for the promotion of reductive elimination from transition metals.

General Description

N-Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions.
NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine.

N-Fluorobenzenesulfonimide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Fluorobenzenesulfonimide Suppliers

Americas 1 Belgium 2 China 381 Europe 5 France 2 Germany 5 India 13 Italy 1 Japan 6 Switzerland 3 United Kingdom 14 United States 47 Global 480
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
WBV international Limited
Tel
--
Fax
--
Email
kelvin@webringvalue.com
Country
United States
ProdList
51
Advantage
0
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
Brightek LLC
Tel
--
Fax
--
Country
United States
ProdList
782
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Wilshire Technologies, Inc.
Tel
--
Fax
--
Email
info@wilshiretechnologies.com
Country
United States
ProdList
893
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Spectrum Chemical Mfg. Corp.
Tel
--
Fax
--
Email
marketing@spectrumchemical.com
Country
United States
ProdList
3113
Advantage
60
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
QVENTAS INC.
Tel
--
Fax
--
Email
mike@qventas.com
Country
United States
ProdList
383
Advantage
47
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
Angene International Limited
Tel
--
Fax
--
Email
sales@angenechemical.com
Country
United States
ProdList
100
Advantage
50
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
TimTec Corporation
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
58
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Honeywell Specialty Chemicals Seelze GmbH
Tel
--
Fax
--
Email
ofc@honeywell.com
Country
United States
ProdList
639
Advantage
87
Syntech Solutions
Tel
--
Fax
--
Email
service@syntechsource.com
Country
United States
ProdList
110
Advantage
39
More
Less

View Lastest Price from N-Fluorobenzenesulfonimide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
N-Fluorobenzenesulfonimide 133745-75-2
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Month
Release date
2024-04-28
Hebei Yanxi Chemical Co., Ltd.
Product
N-Fluorobenzenesulfonimide 133745-75-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 tons
Release date
2024-01-30
Hebei Chuanghai Biotechnology Co,.LTD
Product
N-Fluorobenzenesulfonimide 133745-75-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-22

133745-75-2, N-FluorobenzenesulfonimideRelated Search:

Sulfanilamide Bis(2-ethylhexyl)amine Novaluron Benzenesulfonamide Trifluoromethanesulfonamide Triethanolamine Triethylamine N-Ethylmethylamine p-Toluenesulfonamide Dibenzylamine N-Iodosuccinimide 2,3-Difluoro-4-ethoxybenzeneboronic acid 4-BROMO-2,6-DIFLUOROBENZYL BROMIDE 2,4-Dichloro-5-fluoropyrimidine 3,4,5-Trifluorophenylacetic acid 4-Bromo-2,6-difluorobenzoic acid 2-Methylaminoethanol Mepiquat chloride

  • NFSI
  • N-FLUOROBENZENESULFONAMIDE
  • N-FLUOROBENZENESULFONIMIDE
  • N-FLUOROBENZENESULPHONIMIDE
  • N-FLUOROBIS(PHENYLSULFONYL)AMINE
  • N-FLUORODIBENZENESULFONAMIDE
  • N-Fluorobenzenesulfonimide(NFSI)
  • N-FluorobenzenesulfonMide (NFA)
  • N-FluorobenzenesulfoniMide, 97% 5GR
  • N-Fluorobis(phenylsulfonyl)amine NFSI NFBS
  • N-fluoro-N-(phenylsulfonyl)benzenesulfonaMide, NFSI
  • Bis(phenylsulphonyl)(fluoro)amine
  • N-Fluoro-N-(phenylsulphonyl)benzenesulphonamide, N-Fluorodibenzenesulphonimide, NFSI
  • bis(phenylsulfonyl)fluoroamine (N-FLUOROBENZENESULFONIMIDE)
  • Bis(phenylsulfonyl)fluoroamine
  • N-Fluorobenzenesulfonimide,97%
  • N-Fluorobenzenesulfonimide, N-Fluorodibenzenesulfonimide, NFSI
  • N-Fluorodi(benzenesulfonyl)amine, N-Fluorodibenzenesulfonimide, NFSI
  • N-fluoro-N-(phenylsulfonyl)benzenesulfonamide
  • N-Fluorobenzenesulfonimide ,98%
  • N-(benzenesulfonyl)-S-phenylfluoranesulfonamido
  • SOLI-002
  • N-Fluorobisbenzenesulphonimide
  • N-Fuoro-N-(phenylsulfonyl)-benzenesulfonamide
  • N-FluorobenzenesulfoniMide 97%
  • <i>N</i>-Fluorobenzenesulfonimide
  • N-Fluorobenzenesulfonmide
  • N-FLUORODIBENZENESULFONIMIDE
  • N-FLUORODI(BENZENESULFONYL)AMINE
  • N-Fluorodibenzenesulfonimide (NFSI)
  • N-Fluorobisbenzenesulphonimide, NFSI
  • N-Fluorobenzenesulfonmide (NFSi)
  • NFSI (N-Fluorobenzenesulfonimide)
  • N-Fluoro Dibenzenesulfonic amide
  • Benzenesulfonamide, N-fluoro-N-(phenylsulfonyl)-
  • accufluor nfsi
  • N-Fluorobenzenesulfonimide [Fluorinating Reagent]
  • -Fluorobenzenesulfonimide
  • N-Fluorobenzenesulfonimide[FluorinatingReagent]&gt
  • N-Fluorobenzenesulfonimide, 98%, for synthesis
  • N-Fluorobenzenesulphonimide，97%
  • N-fluorobenzene sulfonamide (NFSI)
  • NFBS
  • N-Fluorobenzenesulfonimide ISO 9001：2015 REACH
  • N-fluorobenzene sulfonate
  • N-(benzenesulfonyl)-N-fluorobenzenesulfonamide
  • Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine 1206525-47-4
  • N-fluorobisbenzensulfonamide
  • N-fluorobisbenzenesulfonamide
  • 133745-75-2
  • 13745-75-2
  • C12H10NO4FS2
  • C12H10FNO4S2
  • C12H10FN4S2
  • C12H14FNO4S2
  • C6H5SO22NF
  • C12F1H10N1O4S2
  • C-X Bond Formation (Halogen)