H-GLU(OBZL)-OTBU HCL

Product Name: H-GLU(OBZL)-OTBU HCL
CAS No.: 105590-97-4
Chemical Name: H-GLU(OBZL)-OTBU HCL
Synonyms: H-Glu(OBzl)-OtBu;Glu(Obzl)OtBu.HCl;H-GLU(OBZL-OTBU HC;H-GLU(OBZL)-OTBU HCL;L-Glu(OBzl)-OtBu·HCl;H-L-GLU(BZL)-OTBU HCL;H-L-GLU(OBZL)-OTBU HCL;GLUTAMIC ACID(OBZL)-OTBU HCL;H-Glu(Obzl)-Otbu hydrochloride;H-GLU(OBZL)-OTBU HCL USP/EP/BP
CBNumber: CB4161628
Molecular Formula: C16H24ClNO4
Formula Weight: 329.82
MOL File: 105590-97-4.mol

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H-GLU(OBZL)-OTBU HCL Property

Melting point:: 104-107°C
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO, Methanol
form: Solid
color: Off-White
InChI: InChI=1/C16H23NO4.ClH/c1-16(2,3)21-15(19)13(17)9-10-14(18)20-11-12-7-5-4-6-8-12;/h4-8,13H,9-11,17H2,1-3H3;1H/t13-;/s3
InChIKey: TWBZXIOAVCJDKR-PHCOUKOGNA-N
SMILES: C1(C=CC=CC=1)COC(=O)CC[C@H](N)C(=O)OC(C)(C)C.Cl |&1:12,r|

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: G598185
Product name: H-Glu(obzl)-otbuHydrochloride
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: X8766
Product name: H-Glu(OBzl)-OtBuHCl
Packaging: 10g
Price: $101
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0017611
Product name: (5-BENZYL-1-TERT-BUTYL-2-AMINOPENTANEDIOATE HYDROCHLORIDE
Purity: 98.00%
Packaging: 1G
Price: $139.65
Updated: 2021/12/16

Activate Scientific

Product number: AS38878
Product name: (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride
Purity: 97% ee
Packaging: 25g
Price: $239
Updated: 2021/12/16

Activate Scientific

Product number: AS38878
Product name: (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride
Purity: 97% ee
Packaging: 1g
Price: $22
Updated: 2021/12/16

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H-GLU(OBZL)-OTBU HCL Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

L-Glutamic Acid 1-(1,1-Dimethylethyl) 5-(Phenylmethyl) Ester Hydrochloride, is a versatile building block in the peptide chemistry. It can be used in the synthesis of series of dynamic peptides.

Uses

H-Glu(obzl)-otbu HCl

Synthesis

540-88-5

1676-73-9

105590-97-4

The general procedure for the synthesis of (S)-5-benzyl 1-tert-butyl 2-aminoglutarate hydrochloride from tert-butyl acetate and L-glutamic acid 5-benzyl ester was as follows: L-glutamic acid 5-benzyl ester (75 g) was dissolved in 750 ml of tert-butyl acetate, and the temperature of the reaction system was maintained at a temperature of less than 5°C by cooling the system with ice water from an external source. 26 ml of perchloric acid was added dropwise slowly in this condition, and after completion of addition, the temperature of the reaction system was raised to 25°C. The reaction was monitored by TLC until complete conversion of L-glutamic acid 5-benzyl ester. After completion of the addition, the temperature of the reaction system was raised to 25°C and the reaction was monitored by TLC until complete conversion of L-glutamic acid 5-benzyl ester. After the reaction was completed, the pH of the reaction solution was adjusted to 7-8 with aqueous sodium carbonate, and the aqueous and organic layers were separated. The organic layer was washed sequentially with water and brine and subsequently dried with anhydrous sodium sulfate. After filtration to remove the desiccant, tert-butyl acetate was removed by vacuum distillation at 50°C to obtain an oil. The oily substance was diluted with a small amount of ether and the pH was subsequently adjusted to 4-5 by addition of a pre-prepared ether hydrochloride solution, at which time the product precipitated. The precipitate was collected by filtration and dried to give 90 g of (S)-5-benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride with a purity of 98.5% and a final yield of 80%.

References

[1] Patent: CN105541649, 2016, A. Location in patent: Paragraph 0014

H-GLU(OBZL)-OTBU HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-GLU(OBZL)-OTBU HCL Suppliers

China 120 Germany 4 India 5 Japan 2 Switzerland 1 United Kingdom 2 United States 13 Global 147

Shanghai Kaipu New Biotechnology Co. , Ltd.

Tel: 17821452002; 17821452002
Email: info@shanghaikaipuxin.com
Country: China
ProdList: 35
Advantage: 58

Shanghai Troedsson Technology Co., LTD

Tel: 13482681346 18117455885
Email: qihongchem@163.com
Country: China
ProdList: 8722
Advantage: 58

SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD

Tel: 0838-2809458 13350585791
Email: pharm@biots.cn
Country: China
ProdList: 672
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 15618770481
Fax: 021-64823266
Email: yhx@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070 13770331960
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16027
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

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View Lastest Price from H-GLU(OBZL)-OTBU HCL manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: L-Glu(Obzl)-Otbu.HCl 105590-97-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-26

Career Henan Chemical Co

Product: H-GLU(OBZL)-OTBU HCL 105590-97-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-22

105590-97-4, H-GLU(OBZL)-OTBU HCLRelated Search:

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105590-97-4

626-64-1

C16H24ClNO4