CHAETOMIN
- Product Name
- CHAETOMIN
- CAS No.
- 1403-36-7
- Chemical Name
- CHAETOMIN
- Synonyms
- CTM;CS-1;HSF4;SSFA2;CHETOMIN;CHAETOMIN;NSC 289491;CHETOMIN(RG);DKFZp313O1039;Chetomin,Chaetomin
- CBNumber
- CB4173948
- Molecular Formula
- C31H30N6O6S4
- Formula Weight
- 710.87
- MOL File
- 1403-36-7.mol
CHAETOMIN Property
- Melting point:
- 218-220℃ (chloroform )
- Density
- 1.78±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- Off-white to fawn solid.
- pka
- 12.69±0.10(Predicted)
- color
- Off-white to fawn
N-Bromosuccinimide Price
- Product number
- C9623
- Product name
- Chetomin
- Purity
- from Chaetomium cochliodes, ≥98% (HPLC)
- Packaging
- 1mg
- Price
- $265
- Updated
- 2024/03/01
- Product number
- SAB1403947
- Product name
- Monoclonal Anti-HSF4 antibody produced in mouse
- Purity
- clone 3G3, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $524
- Updated
- 2024/03/01
- Product number
- C9623
- Product name
- Chetomin
- Purity
- from Chaetomium cochliodes, ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $792
- Updated
- 2024/03/01
- Product number
- 14437
- Product name
- Chetomin
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- 14437
- Product name
- Chetomin
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $549
- Updated
- 2024/03/01
CHAETOMIN Chemical Properties,Usage,Production
Uses
Chetomin is an antibacterial agent and inhibitor of HIF.
Definition
ChEBI: An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity.
Biochem/physiol Actions
Chetomin is a natural metabolite produced by several species of the genus Chaetomium. Chetomin is an epidithiodioxopiperazine known to disrupt the hypoxia-inducible factor (HIF) pathway. Chetomin blocks the interaction of HIF1α and HIF2α with transcriptional co-activators p300 and cAMP response element binding (CREB) binding protein (CBP), thereby attenuating hypoxia-inducible transcription. Disrupting the ability of tumors to adapt to hypoxia leads to decreased tumor growth and can serve as an antitumor stratagy. Chetomin also suppresses the proliferation of LPS-induced mouse spleen lymphocytes.
storage
+4°C
CHAETOMIN Preparation Products And Raw materials
Raw materials
Preparation Products
CHAETOMIN Suppliers
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35906
- Advantage
- 56
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51471
- Advantage
- 80
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9709
- Advantage
- 58
- Tel
- 86-(0)29-85992781 17792393971
- info@lynnchem.com
- Country
- China
- ProdList
- 4587
- Advantage
- 58
- Tel
- 020-31155029 18902330969
- Fax
- 020-31155029
- sales@tomums.cn
- Country
- China
- ProdList
- 4698
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6313
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9414
- Advantage
- 58
- Tel
- 18584079237
- 312074905@qq.com
- Country
- China
- ProdList
- 2507
- Advantage
- 58
- Tel
- 400-820-6829
- sales@mitachieve.com
- Country
- China
- ProdList
- 8864
- Advantage
- 58
- Tel
- 0571-89903882 13626641628
- jiangnan@huidabiotech.com
- Country
- China
- ProdList
- 3661
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8141
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44941
- Advantage
- 58
- Tel
- 0519-85524369
- 3477467573@qq.com
- Country
- China
- ProdList
- 8618
- Advantage
- 58
- Tel
- 021-4007787-550 400-7787-550
- 2850202386@qq.com
- Country
- China
- ProdList
- 10618
- Advantage
- 58
- Tel
- 0571-0571-89903882 15990081639
- sunshixuan@huidabiotech.com
- Country
- China
- ProdList
- 3705
- Advantage
- 58
- Tel
- 13549236410
- sales@invivochem.cn
- Country
- China
- ProdList
- 6712
- Advantage
- 58
- Tel
- 4001650900 13817534909
- 3003940895@qq.com
- Country
- China
- ProdList
- 9345
- Advantage
- 58
- Tel
- 021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29803
- Advantage
- 58
- Tel
- 0513-66337626 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 4030
- Advantage
- 58
- Tel
- 025-52151215 13915956535 13915956535
- 570945402@qq.com
- Country
- China
- ProdList
- 9733
- Advantage
- 58
- Tel
- 025-66113011 18112977050
- cb5@aikonchem.com
- Country
- China
- ProdList
- 10529
- Advantage
- 58
- Tel
- 400-901-9800 18611424007
- cis@bioss.com.cn
- Country
- China
- ProdList
- 9518
- Advantage
- 58
- Tel
- 18162595016
- 3287908757@qq.com
- Country
- China
- ProdList
- 9887
- Advantage
- 58
- Tel
- 18988968278
- sales@ubiochem.com
- Country
- China
- ProdList
- 9146
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6846
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1861586486@qq.com
- Country
- CHINA
- ProdList
- 6652
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1562893815@qq.com
- Country
- CHINA
- ProdList
- 6942
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@abace-biology.com
- Country
- CHINA
- ProdList
- 2529
- Advantage
- 58
- Tel
- --
- Fax
- --
- yangmei@bioneeds.net
- Country
- CHINA
- ProdList
- 6999
- Advantage
- 58
- Tel
- --
- Fax
- --
- 912529879@qq.com
- Country
- CHINA
- ProdList
- 6852
- Advantage
- 58
- Tel
- --
- Fax
- --
- 3128828699@qq.com
- Country
- CHINA
- ProdList
- 6509
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1985563437@qq.com
- Country
- CHINA
- ProdList
- 6172
- Advantage
- 58
- Tel
- --
- Fax
- --
- john.st@163.com
- Country
- CHINA
- ProdList
- 1472
- Advantage
- 58
- Tel
- --
- Fax
- --
- 978560024@qq.com
- Country
- CHINA
- ProdList
- 6011
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6661
- Advantage
- 58
- Tel
- --
- Fax
- --
- jijinhuaxue@sina.com
- Country
- CHINA
- ProdList
- 6617
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@f-biology.com
- Country
- CHINA
- ProdList
- 6039
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- CHINA
- ProdList
- 6057
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1914109725@qq.com
- Country
- CHINA
- ProdList
- 6530
- Advantage
- 58
- Tel
- --
- Fax
- --
- lyn@biopike.com.cn
- Country
- CHINA
- ProdList
- 6629
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@qwbio.com
- Country
- China
- ProdList
- 6912
- Advantage
- 50
- Tel
- --
- Fax
- --
- huaxiabio@163.com
- Country
- CHINA
- ProdList
- 6122
- Advantage
- 58
- Tel
- --
- Fax
- --
- 2453006496@qq.com
- Country
- CHINA
- ProdList
- 6192
- Advantage
- 58
- Tel
- --
- Fax
- --
- WHIGA22@126.COM
- Country
- CHINA
- ProdList
- 6748
- Advantage
- 58
- Tel
- --
- Fax
- --
- zikerbio@163.com
- Country
- CHINA
- ProdList
- 6478
- Advantage
- 58
- Tel
- --
- Fax
- --
- 3007606172@qq.com
- Country
- CHINA
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- SHYIJIEBIO@126.COM
- Country
- CHINA
- ProdList
- 3510
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenxue_gz@163.com
- Country
- CHINA
- ProdList
- 6618
- Advantage
- 58