HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

Product Name: HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
CAS No.: 19179-12-5
Chemical Name: HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
Synonyms: cyclo(glycylprolyl);HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;octahydropyrrolo[1,2-a]piperazine-1,4-dione;Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-;(Pro-Gly).Hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione;2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione;Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- (6CI,7CI,8CI,9CI)
CBNumber: CB4418533
Molecular Formula: C7H10N2O2
Formula Weight: 154.17
MOL File: 19179-12-5.mol

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HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Property

Boiling point:: 447.9±34.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
pka: 13.21±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 123479
Product name: Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Purity: 95+%
Packaging: 1g
Price: $364
Updated: 2021/12/16

AK Scientific

Product number: 6826AJ
Product name: Hexahydropyrrolo[1,2-A]pyrazine-1,4-dione
Packaging: 5g
Price: $566
Updated: 2021/12/16

Crysdot

Product number: CD11175905
Product name: Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Purity: 95+%
Packaging: 5g
Price: $371
Updated: 2021/12/16

Alichem

Product number: 19179125
Product name: Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Packaging: 5g
Price: $390
Updated: 2021/12/16

Arctom

Product number: CFN90272
Product name: Cyclo(Pro-Gly)
Packaging: 10mg
Price: $332
Updated: 2021/12/16

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HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Chemical Properties,Usage,Production

Uses

Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].

Definition

ChEBI: Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

in vivo

Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation^[3].

References

[1] Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. DOI:10.1007/s11356-015-5377-7
[2] Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016.
[3] T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52. DOI:10.1016/0014-5793(96)00722-3

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Suppliers

China 33 Europe 1 Germany 1 United States 11 Global 46

ForeChem (Nantong) Technology Co.,Ltd.

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19179-12-5, HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONERelated Search:

VERRUCULOGEN Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3R,8aS)- (9CI) ROQUEFORTINE C Aranotine CYCLO(-D-LEU-D-PRO) Chaetocin gypsetin BIS(METHYLTHIO)GLIOTOXIN fumitremorgin B CYCLO(-LEU-PRO) GLIOTOXIN CYCLO(-GLY-PRO) CYCLO(-HIS-PRO) CYCLO(-PHE-PRO) CYCLO(-HIS-D-PRO) CHAETOMIN HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE CYCLO(-D-HIS-PRO)

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- (6CI,7CI,8CI,9CI)

cyclo(glycylprolyl)

octahydropyrrolo[1,2-a]piperazine-1,4-dione

2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(Pro-Gly).Hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-

19179-12-5

PIPERIDINE

PYRROLE