CYCLOOCTANONE

Product Name: CYCLOOCTANONE
CAS No.: 502-49-8
Chemical Name: CYCLOOCTANONE
Synonyms: CYCLOOCTAN-1-ONE;Oxocyclooctane;Azelaone;ooctanone;CyclooCLanone;CYCLOOCTANONE;Cyclooctanone,98%;Cyclooctanone,97%;Cyclooctanone 98%;Cyclooctanone >
CBNumber: CB4182005
Molecular Formula: C8H14O
Formula Weight: 126.2
MOL File: 502-49-8.mol

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CYCLOOCTANONE Property

Melting point:: 32-41 °C (lit.)
Boiling point:: 195-197 °C (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
refractive index: 1.4694
Flash point:: 163 °F
storage temp.: Sealed in dry,Room Temperature
solubility: 15g/l
form: Crystalline Low Melting Solid
color: Colorless to white
PH: 7 (15g/l, H2O, 20℃)
Water Solubility: Soluble in water at 20°C 15g/L. Soluble in acetone, alcohol, chloroform, methanol and benzene.
BRN: 1280738
InChIKey: IIRFCWANHMSDCG-UHFFFAOYSA-N
LogP: 2.11
CAS DataBase Reference: 502-49-8(CAS DataBase Reference)
EPA Substance Registry System: Cyclooctanone (502-49-8)

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Safety

Hazard Codes: C,Xi
Risk Statements: 34-52/53-36/37/38
Safety Statements: 45-36/37/39-26-61
RIDADR: 1759
WGK Germany: 3
RTECS: GX9800000
TSCA: Yes
HazardClass: 8
HS Code: 29142990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C109800
Product name: Cyclooctanone
Purity: 98%
Packaging: 25g
Price: $59.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: C109800
Product name: Cyclooctanone
Purity: 98%
Packaging: 100g
Price: $131
Updated: 2024/03/01

TCI Chemical

Product number: C0504
Product name: Cyclooctanone
Purity: >97.0%(GC)
Packaging: 10g
Price: $18
Updated: 2024/03/01

TCI Chemical

Product number: C0504
Product name: Cyclooctanone
Purity: >97.0%(GC)
Packaging: 25g
Price: $31
Updated: 2024/03/01

Alfa Aesar

Product number: B20911
Product name: Cyclooctanone, 98%
Packaging: 25g
Price: $32.65
Updated: 2024/03/01

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CYCLOOCTANONE Chemical Properties,Usage,Production

Chemical Properties

colorless to white crystalline low melting solid

Uses

Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. It is also used in the synthesis of 14-membered lactones.

Synthesis Reference(s)

Journal of the American Chemical Society, 92, p. 5276, 1970 DOI: 10.1021/ja00720a078
The Journal of Organic Chemistry, 49, p. 3912, 1984 DOI: 10.1021/jo00195a007
Tetrahedron Letters, 36, p. 2921, 1995 DOI: 10.1016/0040-4039(95)00467-Q

Purification Methods

Purify the ketone by sublimation after drying with Linde type 13X molecular sieves. The semicarbazone has m 168-169o (from dioxane) [Kohler et al. J Am Chem Soc 61 1060 1939]. The oxime has m 36-37o after subliming at high vacuum or distillation and has b 128-129o /14mm. The iso-oxime has m 72-73o [Ruzicka et al. Helv Chim Acta 32 548 1949]. [Beilstein 7 III 77, 7 IV 49.]

CYCLOOCTANONE Preparation Products And Raw materials

Raw materials

Sodium hydride P-XYLENE Azelaic acid Methanol Sodium hydroxide Sulfuric acid

Preparation Products

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CYCLOOCTANONE Suppliers

Americas 1 Belgium 4 Canada 1 China 239 Europe 2 Germany 10 India 19 Japan 2 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 7 United States 34 Global 323

Toronto Research Chemicals

Tel: --
Fax: --
Email: info@trc-canada.com
Country: Canada
ProdList: 6038
Advantage: 71

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View Lastest Price from CYCLOOCTANONE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Cyclooctanone 502-49-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Honest Joy Holdings Limited

Product: Cyclooctanone 502-49-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.3%
Supply Ability: 100 tons
Release date: 2022-02-18

Zhuozhou Wenxi import and Export Co., Ltd

Product: Cyclooctanone 502-49-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

502-49-8, CYCLOOCTANONERelated Search:

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CYCLOOCTAN-1-ONE

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502-49-8

402-49-8

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