ChemicalBook > CAS DataBase List > CYCLOOCTANONE

CYCLOOCTANONE

Product Name
CYCLOOCTANONE
CAS No.
502-49-8
Chemical Name
CYCLOOCTANONE
Synonyms
CYCLOOCTAN-1-ONE;Oxocyclooctane;Azelaone;ooctanone;CyclooCLanone;CYCLOOCTANONE;Cyclooctanone,98%;Cyclooctanone,97%;Cyclooctanone 98%;Cyclooctanone >
CBNumber
CB4182005
Molecular Formula
C8H14O
Formula Weight
126.2
MOL File
502-49-8.mol
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CYCLOOCTANONE Property

Melting point:
32-41 °C (lit.)
Boiling point:
195-197 °C (lit.)
Density 
0.958 g/mL at 25 °C (lit.)
refractive index 
1.4694
Flash point:
163 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
15g/l
form 
Crystalline Low Melting Solid
color 
Colorless to white
PH
7 (15g/l, H2O, 20℃)
Water Solubility 
Soluble in water at 20°C 15g/L. Soluble in acetone, alcohol, chloroform, methanol and benzene.
BRN 
1280738
InChIKey
IIRFCWANHMSDCG-UHFFFAOYSA-N
LogP
2.11
CAS DataBase Reference
502-49-8(CAS DataBase Reference)
EPA Substance Registry System
Cyclooctanone (502-49-8)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34-52/53-36/37/38
Safety Statements 
45-36/37/39-26-61
RIDADR 
1759
WGK Germany 
3
RTECS 
GX9800000
TSCA 
Yes
HazardClass 
8
HS Code 
29142990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C109800
Product name
Cyclooctanone
Purity
98%
Packaging
25g
Price
$59.1
Updated
2024/03/01
Sigma-Aldrich
Product number
C109800
Product name
Cyclooctanone
Purity
98%
Packaging
100g
Price
$131
Updated
2024/03/01
TCI Chemical
Product number
C0504
Product name
Cyclooctanone
Purity
>97.0%(GC)
Packaging
10g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
C0504
Product name
Cyclooctanone
Purity
>97.0%(GC)
Packaging
25g
Price
$31
Updated
2024/03/01
Alfa Aesar
Product number
B20911
Product name
Cyclooctanone, 98%
Packaging
25g
Price
$32.65
Updated
2024/03/01
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CYCLOOCTANONE Chemical Properties,Usage,Production

Chemical Properties

colorless to white crystalline low melting solid

Uses

Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. It is also used in the synthesis of 14-membered lactones.

Synthesis Reference(s)

Journal of the American Chemical Society, 92, p. 5276, 1970 DOI: 10.1021/ja00720a078
The Journal of Organic Chemistry, 49, p. 3912, 1984 DOI: 10.1021/jo00195a007
Tetrahedron Letters, 36, p. 2921, 1995 DOI: 10.1016/0040-4039(95)00467-Q

Purification Methods

Purify the ketone by sublimation after drying with Linde type 13X molecular sieves. The semicarbazone has m 168-169o (from dioxane) [Kohler et al. J Am Chem Soc 61 1060 1939]. The oxime has m 36-37o after subliming at high vacuum or distillation and has b 128-129o /14mm. The iso-oxime has m 72-73o [Ruzicka et al. Helv Chim Acta 32 548 1949]. [Beilstein 7 III 77, 7 IV 49.]

CYCLOOCTANONE Preparation Products And Raw materials

Raw materials

Sodium hydride P-XYLENE Azelaic acid Methanol Sodium hydroxide Sulfuric acid

Preparation Products

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CYCLOOCTANONE Suppliers

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View Lastest Price from CYCLOOCTANONE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Cyclooctanone 502-49-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Honest Joy Holdings Limited
Product
Cyclooctanone 502-49-8
Price
US $0.00/KG
Min. Order
1KG
Purity
97.3%
Supply Ability
100 tons
Release date
2022-02-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
Cyclooctanone 502-49-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

502-49-8, CYCLOOCTANONERelated Search:

4-Hydroxy-2-adamantone 10-Deacetylbaccatin III 2-Chloro-1-cyclooctanone 2-Adamantanone CYCLOOCTANONE ENDRIN KETONE 5-Hydroxyadamantan-2-one 7-methylidenebicyclo[3.3.1]nonan-3-one BICYCLO[3.3.1]NONANE-2,6-DIONE Baccatine III CIS-1,5-DIMETHYLBICYCLO[3.3.0]OCTANE-3,7-DIONE PSEUDO-PELLETIERINE 9-Benzyl-9-azabicyclo[3.3.1]nonan-3-one PSEUDOPELLETIERINE HYDROCHLORIDE CYCLOOCTANONE ISOOXIME Cyclooctanone oxime, 98+%,CYCLOOCTANONE OXIME 1-aza-2-cyclooctanon INGENOL 3,20-DIBENZOATE

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  • Organic Building Blocks
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  • C7 to C8
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  • Aliphatics, Pharmaceuticals, Intermediates & Fine Chemicals
  • C7 to C8
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