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3-Fluorophenethylamine

Product Name
3-Fluorophenethylamine
CAS No.
404-70-6
Chemical Name
3-Fluorophenethylamine
Synonyms
RARECHEM AL BW 0208;3-FLUOROPHENETHYLAMINE;3-Fluoro-benzeneethanaMine;3-Fluorophenethylamine ,99%;2-(3-FLUOROPHENYL)ETHYLAMINE;Benzeneethanamine, 3-fluoro-;2-(3-Fluorophenyl)ethylamine>3-FluorophenethylaMine, 99% 5GR;3-FluorophenethylaMine, 99% 25GR;1-Amino-2-(3-fluorophenyl)ethane
CBNumber
CB4182803
Molecular Formula
C8H10FN
Formula Weight
139.17
MOL File
404-70-6.mol
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3-Fluorophenethylamine Property

Boiling point:
87 °C/15 mmHg (lit.)
Density 
1.066 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.509(lit.)
Flash point:
181 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
9.65±0.10(Predicted)
form 
Liquid
Specific Gravity
1.066
color 
Clear colorless to pale yellow
Sensitive 
Air Sensitive
CAS DataBase Reference
404-70-6(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 2735 8/PG 2
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
347051
Product name
3-Fluorophenethylamine
Purity
99%
Packaging
5g
Price
$65
Updated
2023/01/07
Sigma-Aldrich
Product number
347051
Product name
3-Fluorophenethylamine
Purity
99%
Packaging
25g
Price
$308
Updated
2023/01/07
TCI Chemical
Product number
F0930
Product name
2-(3-Fluorophenyl)ethylamine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$86
Updated
2025/07/31
TCI Chemical
Product number
F0930
Product name
2-(3-Fluorophenyl)ethylamine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$342
Updated
2025/07/31
TRC
Product number
F593870
Product name
3-Fluorophenethylamine
Packaging
1g
Price
$55
Updated
2021/12/16
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3-Fluorophenethylamine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to pale yellow liquid

Uses

3-Fluorophenethylamine may be used in the synthesis of:

  • N-(3-florophenyl)ethylcaffeamide and its anti-inflammatory activity was evaluated
  • N-{2-[(3-fluorophenyl)ethyl]}-2-methylpropanamide
  • N-(3′-fluorophenyl)ethyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol

Synthesis

501-00-8

404-70-6

General procedure for the synthesis of 2-(3-fluorophenyl)ethylamine from m-fluorophenylacetonitrile: The standard procedure for the reduction of nitrile using KBH4 and CuCl2 is as follows: to a 10 mL round-bottomed flask were added m-fluorophenylacetonitrile (0.15 g, 1 mmol), KBH4 (0.17 g, 3 mmol), CuCl2 (0.03 g, 0.25 mmol), and an 80% isopropanol solution (prepared from 1.6 mL isopropanol and 0.4 mL water). The reaction mixture was stirred at 60 °C and the progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio of dichloromethane: methanol = 10:1) to confirm that the reaction was completed within 8 hours. Upon completion of the reaction, the mixture was cooled to 25 °C and the solvent was subsequently removed by rotary evaporator. Ethyl acetate (5 mL) was added to the residue for dissolution and washed sequentially with water (1 mL) and saturated saline (1 mL). The organic layer was dried over anhydrous Na2SO4, filtered and concentrated in vacuum to give the crude product 2-(3-fluorophenyl)ethylamine.

References

[1] Asian Journal of Chemistry, 2015, vol. 27, # 10, p. 3564 - 3566
[2] Patent: WO2011/11522, 2011, A2. Location in patent: Page/Page column 58
[3] Patent: WO2012/79079, 2012, A1. Location in patent: Page/Page column 63-64
[4] Advanced Synthesis and Catalysis, 2012, vol. 354, # 16, p. 2997 - 3008
[5] Journal of Medicinal Chemistry, 1986, vol. 29, # 7, p. 1302 - 1305

3-Fluorophenethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Fluorophenethylamine Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
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View Lastest Price from 3-Fluorophenethylamine manufacturers

Honest Joy Holdings Limited
Product
3-Fluorophenethylamine 404-70-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.6%
Supply Ability
100 tons
Release date
2022-02-21
Nanjing jinheyou Trading Co., Ltd.
Product
3-Fluorophenethylamine 404-70-6
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-11-20
Career Henan Chemical Co
Product
3-Fluorophenethylamine 404-70-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 334
Release date
2019-09-01

404-70-6, 3-FluorophenethylamineRelated Search:


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