3-Fluorophenethylamine
- Product Name
- 3-Fluorophenethylamine
- CAS No.
- 404-70-6
- Chemical Name
- 3-Fluorophenethylamine
- Synonyms
- RARECHEM AL BW 0208;3-FLUOROPHENETHYLAMINE;3-Fluoro-benzeneethanaMine;3-Fluorophenethylamine ,99%;2-(3-FLUOROPHENYL)ETHYLAMINE;Benzeneethanamine, 3-fluoro-;2-(3-Fluorophenyl)ethylamine>3-FluorophenethylaMine, 99% 5GR;3-FluorophenethylaMine, 99% 25GR;1-Amino-2-(3-fluorophenyl)ethane
- CBNumber
- CB4182803
- Molecular Formula
- C8H10FN
- Formula Weight
- 139.17
- MOL File
- 404-70-6.mol
3-Fluorophenethylamine Property
- Boiling point:
- 87 °C/15 mmHg (lit.)
- Density
- 1.066 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.509(lit.)
- Flash point:
- 181 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 9.65±0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.066
- color
- Clear colorless to pale yellow
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 404-70-6(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 2735 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 347051
- Product name
- 3-Fluorophenethylamine
- Purity
- 99%
- Packaging
- 5g
- Price
- $65
- Updated
- 2023/01/07
- Product number
- 347051
- Product name
- 3-Fluorophenethylamine
- Purity
- 99%
- Packaging
- 25g
- Price
- $308
- Updated
- 2023/01/07
- Product number
- F0930
- Product name
- 2-(3-Fluorophenyl)ethylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $86
- Updated
- 2025/07/31
- Product number
- F0930
- Product name
- 2-(3-Fluorophenyl)ethylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $342
- Updated
- 2025/07/31
- Product number
- F593870
- Product name
- 3-Fluorophenethylamine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
3-Fluorophenethylamine Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to pale yellow liquid
Uses
3-Fluorophenethylamine may be used in the synthesis of:
- N-(3-florophenyl)ethylcaffeamide and its anti-inflammatory activity was evaluated
- N-{2-[(3-fluorophenyl)ethyl]}-2-methylpropanamide
- N-(3′-fluorophenyl)ethyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol
Synthesis
501-00-8
404-70-6
General procedure for the synthesis of 2-(3-fluorophenyl)ethylamine from m-fluorophenylacetonitrile: The standard procedure for the reduction of nitrile using KBH4 and CuCl2 is as follows: to a 10 mL round-bottomed flask were added m-fluorophenylacetonitrile (0.15 g, 1 mmol), KBH4 (0.17 g, 3 mmol), CuCl2 (0.03 g, 0.25 mmol), and an 80% isopropanol solution (prepared from 1.6 mL isopropanol and 0.4 mL water). The reaction mixture was stirred at 60 °C and the progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio of dichloromethane: methanol = 10:1) to confirm that the reaction was completed within 8 hours. Upon completion of the reaction, the mixture was cooled to 25 °C and the solvent was subsequently removed by rotary evaporator. Ethyl acetate (5 mL) was added to the residue for dissolution and washed sequentially with water (1 mL) and saturated saline (1 mL). The organic layer was dried over anhydrous Na2SO4, filtered and concentrated in vacuum to give the crude product 2-(3-fluorophenyl)ethylamine.
References
[1] Asian Journal of Chemistry, 2015, vol. 27, # 10, p. 3564 - 3566
[2] Patent: WO2011/11522, 2011, A2. Location in patent: Page/Page column 58
[3] Patent: WO2012/79079, 2012, A1. Location in patent: Page/Page column 63-64
[4] Advanced Synthesis and Catalysis, 2012, vol. 354, # 16, p. 2997 - 3008
[5] Journal of Medicinal Chemistry, 1986, vol. 29, # 7, p. 1302 - 1305
3-Fluorophenethylamine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Fluorophenethylamine Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- --
- Fax
- --
- labchem-tec@wako-chem.co.jp
- Country
- Japan
- ProdList
- 6819
- Advantage
- 80
View Lastest Price from 3-Fluorophenethylamine manufacturers
- Product
- 3-Fluorophenethylamine 404-70-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.6%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21
- Product
- 3-Fluorophenethylamine 404-70-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-11-20
- Product
- 3-Fluorophenethylamine 404-70-6
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 334
- Release date
- 2019-09-01