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Perospirone hydrochloride

Product Name
Perospirone hydrochloride
CAS No.
129273-38-7
Chemical Name
Perospirone hydrochloride
Synonyms
Lullan;PEROSPIRONE HYDROCHLORIDE HYDRATE;Lulla;sm-9018;D8-Perospirone HCl;2H8]-Perospirone HCl;SM-9018 hydrochloride;PEROSPIRONE HYDROCHLORIDE;Piropilone (hydrochloride);Perospirone HCl hydrate - Bio-X ?
CBNumber
CB4192563
Molecular Formula
C23H31ClN4O2S
Formula Weight
463.04
MOL File
129273-38-7.mol
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Perospirone hydrochloride Property

Melting point:
95-970C
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChIKey
HIZFAPMOZFYELI-GNXQHMNLNA-N
SMILES
C(N1CCN(C2=NSC3C=CC=CC2=3)CC1)CCCN1C([C@@]2([H])CCCC[C@@]2([H])C1=O)=O.Cl |&1:21,27,r|
CAS DataBase Reference
129273-38-7(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2944
Product name
Perospirone Hydrochloride
Packaging
25MG
Price
$135
Updated
2025/07/31
TRC
Product number
P288900
Product name
PerospironeHydrochlorideHydrate
Packaging
1g
Price
$1185
Updated
2021/12/16
Matrix Scientific
Product number
094175
Product name
Perospirone hydrochloride
Purity
95+%
Packaging
250mg
Price
$1418
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000759
Product name
PEROSPIRONE HYDROCHLORIDE TRIHYDRATE
Purity
95.00%
Packaging
100MG
Price
$1732.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000759
Product name
PEROSPIRONE HYDROCHLORIDE TRIHYDRATE
Purity
95.00%
Packaging
250MG
Price
$2232.3
Updated
2021/12/16
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Perospirone hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Serotonin (5-HT2) and dopamine (D2) antagonist (SDA).

Biological Activity

Perospirone (SM-9018) is a typical neuroleptic (antipsychotic) agent th at displays high affinity for 5-HT2, D2 and 5-HT1A receptors (Ki = 0.61, 1.4 and 2.9-1.8 nM, respectively), moderate affinity for alpha 1 and D1 receptors (Ki = 17 and 41 nM, respectively), while exhibiting much reduced affinity for alpha 2 (Ki = 408 nM) and little affinity toward muscarinic, opiate, glutamate, phencyclidine, benzodiazepine or GABAA receptors (Ki >1 μM). SM-9018 antagonizes both D2-dependent (e.g. methamphetamine-induced hyperactivity, apomorphine-induced stereotypy) and 5-HT2-mediated (e.g. tryptamine-induced clonic seizure) activities in vivo, while exhibiting very low cataleptogenic and central depressant activities commonly observed with two other neuroleptics, haloperidol and chlorpromazine.

IC 50

5-HT2A Receptor: 0.6 nM (Ki); D2 Receptor: 1.4 nM (Ki); 5-HT1A Receptor: 2.9 nM (Ki); 5-HT1 Receptor: 18 nM (Ki); D1 Receptor: 41 nM (Ki)

Perospirone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Perospirone hydrochloride Suppliers

Canada 1 China 172 Europe 2 Germany 1 India 2 United Kingdom 6 United States 21 USA 1 Global 206
Zhuhai Free Trade Zone Lizhu Synthetic Pharmaceutical Co., Ltd.
Tel
Fax
NULL
Country
China
ProdList
23
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Eastbang Pharmaceuticals Technology Co., Ltd.
Tel
+86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387
Fax
+86 (20) 39218032
Country
China
ProdList
454
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
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View Lastest Price from Perospirone hydrochloride manufacturers

Dideu Industries Group Limited
Product
Perospirone hydrochloride 129273-38-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
Perospirone hydrochloride 129273-38-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Perospirone hydrochloride 129273-38-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

129273-38-7, Perospirone hydrochlorideRelated Search:

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  • PEROSPIRONE HYDROCHLORIDE
  • PEROSPIRONE HYDROCHLORIDE DIHYDRATE
  • PEROSPIRONE HYDROCHLORIDE HYDRATE
  • 1h-isoindole-1,3(2h)-dione,2-(4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)but
  • monohydrochloride,cis-yl)hexahydro
  • sm-9018
  • (3aR,7aS)-rel-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H- isoindole-1,3(2H)-dione Hydrochloride Trihydrate
  • Lulla
  • Perospirone Hydrochloride Trihydrate
  • (3ar,7as)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione hydrochloride
  • SM-9018 hydrochloride
  • (3aR,7aS)-2-(4-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)butyl)hexahydro-1H-isoindole-1,3(2H)-dione hydrochloride
  • Lullan
  • 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, hydrochloride (1:1), (3aR,7aS)-rel-
  • Perospirone hydrochloride USP/EP/BP
  • 2H8]-Perospirone HCl
  • Piropilone (hydrochloride)
  • Perospirone hydrochloride, 10 mM in DMSO
  • Perospirone HCl hydrate - Bio-X ?
  • rel-(3aR,7aS)-2-(4-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)butyl)hexahydro-1H-isoindole-1,3(2H)-dione hydrochloride
  • D8-Perospirone HCl
  • 129273-38-7
  • 12973-38-7
  • C23H37ClN4O5S
  • C23H30N4O2SHCl
  • C23H30N4O2SHCl2H2O
  • C24H33ClN4O2S
  • Intermediates & Fine Chemicals
  • Pharmaceuticals