N-2-Acetylguanine
- Product Name
- N-2-Acetylguanine
- CAS No.
- 19962-37-9
- Chemical Name
- N-2-Acetylguanine
- Synonyms
- 2-ACETYLGUANINE;N-ACETYLGUANINE;2-N-ACETYLGUANINE;N-2-ACETYLGUANINE;Acyclovir Impurity 5;Ribavirin Impurity 41;N-2-ACETYLGUANINE, 99+%;2-ACETAMIDO-6-HYDROXYPURINE;N-2-Acetylguanine USP/EP/BP;2-acetamide-6-hydroxypurine
- CBNumber
- CB4194385
- Molecular Formula
- C7H7N5O2
- Formula Weight
- 193.16
- MOL File
- 19962-37-9.mol
N-2-Acetylguanine Property
- Melting point:
- 260 °C
- Boiling point:
- 329.37°C (rough estimate)
- Density
- 1.4225 (rough estimate)
- refractive index
- 1.8000 (estimate)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly)
- form
- Powder
- pka
- 9.06±0.20(Predicted)
- color
- White to beige
- Water Solubility
- practically insoluble
- CAS DataBase Reference
- 19962-37-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- HS Code
- 29335995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A1248
- Product name
- 2-Acetamido-6-hydroxypurine
- Purity
- >95.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $206
- Updated
- 2025/07/31
- Product number
- A1248
- Product name
- 2-Acetamido-6-hydroxypurine
- Purity
- >95.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $822
- Updated
- 2025/07/31
- Product number
- A178250
- Product name
- N2-Acetylguanine
- Packaging
- 5g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-W021535
- Product name
- 2-Acetamido-6-hydroxypurine
- Purity
- 99.69%
- Packaging
- 25g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FA07183
- Product name
- N2-Acetylguanine
- Packaging
- 25g
- Price
- $112.5
- Updated
- 2021/12/16
N-2-Acetylguanine Chemical Properties,Usage,Production
Chemical Properties
White Crystalline
Uses
Protected guanine
Synthesis
73-40-5
19962-37-9
The general procedure for the synthesis of N-(6-hydroxy-9H-purin-2-yl)acetamide from guanine is as follows:Example 52 Preparation of N2-acetyl guanine. Guanine (10.1 g) was suspended in N,N-dimethylacetamide (100 ml) followed by the addition of acetic anhydride (20 ml). The reaction mixture was stirred under reflux conditions for 2 h followed by thermal filtration. The filtrate was cooled to room temperature and the precipitated solid was filtered. The solid was suspended in ethanol (66 ml) and stirred for 1.5 hours and then filtered. The resulting solid was placed in 50% ethanol and stirred at reflux for 3 hours, followed by cooling of the solution. The solid product was obtained by filtration, washed with 50% ethanol and dried to give the target compound N2-acetylguanine (9.36 g, 72.7% yield) as a white solid.1H NMR (DMSO-d6) δ 13.14 (broad peak, 1H), 12.14 (broad peak, 1H), 11.67 (broad peak, 1H), 8.10 (broad peak, 1H), 2.28 ( single peak, 3H).
References
[1] Patent: US6034087, 2000, A
[2] Organic Letters, 2015, vol. 17, # 20, p. 4933 - 4935
N-2-Acetylguanine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-2-Acetylguanine manufacturers
- Product
- N-2-Acetylguanine 19962-37-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 1000g
- Release date
- 2021-10-15
- Product
- N2-Acetylguanine 19962-37-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-13
- Product
- N-2-Acetylguanine 19962-37-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-12