2-Methylhydroquinone
- Product Name
- 2-Methylhydroquinone
- CAS No.
- 95-71-6
- Chemical Name
- 2-Methylhydroquinone
- Synonyms
- THQ;TOLUHYDROQUINONE;1,4-Benzenediol, 2-methyl-;METHYLHYDROQUINONE;2-methyl-1,4-hydroquinone;2,5-DIHYDROXYTOLUENE;2-METHYL-1,4-BENZENEDIOL;1,4-Dihydroxy-2-methylbenzene;Toluquinol;p-Toluquinol
- CBNumber
- CB4201720
- Molecular Formula
- C7H8O2
- Formula Weight
- 124.14
- MOL File
- 95-71-6.mol
2-Methylhydroquinone Property
- Melting point:
- 128-130 °C(lit.)
- Boiling point:
- 285°C
- Density
- 1.1006 (rough estimate)
- vapor pressure
- 0.004Pa at 25℃
- refractive index
- 1.4922 (estimate)
- Flash point:
- 172 °C
- storage temp.
- Store below +30°C.
- solubility
- 77g/l
- pka
- pK1:10.03;pK2:11.62 (25°C)
- form
- Crystalline Powder
- color
- Grayish-white to light beige
- Water Solubility
- 77 g/L (25 ºC)
- BRN
- 2041489
- Stability:
- Stable. Combustible. Incompatible with oxidizing agents, strong bases.
- InChIKey
- CNHDIAIOKMXOLK-UHFFFAOYSA-N
- LogP
- 0.9 at 27℃
- CAS DataBase Reference
- 95-71-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,4-Benzenediol, 2-methyl-(95-71-6)
- EPA Substance Registry System
- 2-Methylhydroquinone (95-71-6)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36
- RIDADR
- 2811
- WGK Germany
- 2
- RTECS
- MX6700000
- Autoignition Temperature
- 851 °F
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29072900
- Toxicity
- LD50 orally in Rabbit: 200 - 400 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 8.20801
- Product name
- 2-Methylhydroquinone
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $45.3
- Updated
- 2024/03/01
- Product number
- 112968
- Product name
- Methylhydroquinone
- Purity
- 99%
- Packaging
- 250g
- Price
- $98.5
- Updated
- 2024/03/01
- Product number
- 112968
- Product name
- Methylhydroquinone
- Purity
- 99%
- Packaging
- 1kg
- Price
- $256
- Updated
- 2024/03/01
- Product number
- M0342
- Product name
- Methylhydroquinone
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $28
- Updated
- 2024/03/01
- Product number
- M0342
- Product name
- Methylhydroquinone
- Purity
- >98.0%(T)
- Packaging
- 100g
- Price
- $82
- Updated
- 2024/03/01
2-Methylhydroquinone Chemical Properties,Usage,Production
Chemical Properties
white solid
Uses
Antioxidant, polymerization inhibitor.
Uses
Methylhydroquinone is used as stabilizer and antioxidant in aerylic monomers to prevent polymerization.
Uses
Methylhydroquinone is a marine fungus metabolite, showing activity as an angiosupressor that interferes with the Akt pathway. Allows for screening of novel inhibitors of angiogenesis.
Definition
ChEBI: A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group.
Synthesis Reference(s)
Tetrahedron, 44, p. 1227, 1988 DOI: 10.1016/S0040-4020(01)85902-0
Tetrahedron Letters, 22, p. 2337, 1981 DOI: 10.1016/S0040-4039(01)82900-2
General Description
Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies.
Purification Methods
Crystallise the quinone from EtOH. [Beilstein 6 IV 5866.]
2-Methylhydroquinone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methylhydroquinone manufacturers
- Product
- 2-Methylhydroquinone 95-71-6
- Price
- US $62.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-24
- Product
- 2-Methylhydroquinone 95-71-6
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200mt/year
- Release date
- 2021-07-15
- Product
- 2-Methylhydroquinone 95-71-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13