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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE

Product Name
BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
CAS No.
122266-55-1
Chemical Name
BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
Synonyms
NHS-SS-BIOTIN;Sulfo-SS-Biotin;Biotin-SS-NHS ester;NHS-SS-biotin,Biotin-SS-NHS;SULFOBIOTIN-X-NHS, CLEAVABLE;BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE;SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE;Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB4216304
Molecular Formula
C19H28N4O6S3
Formula Weight
504.64
MOL File
Mol file
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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Property

storage temp. 
0-6°C
solubility 
≥28.79 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A8006
Product name
NHS-SS-Biotin
Packaging
100mg
Price
$100
Updated
2021/12/16
BroadPharm
Product number
BP-22636
Product name
NHS-SS-biotin
Purity
90%
Packaging
100mg
Price
$290
Updated
2021/12/16
BroadPharm
Product number
BP-22636
Product name
NHS-SS-biotin
Purity
90%
Packaging
1g
Price
$1470
Updated
2021/12/16
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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Chemical Properties,Usage,Production

Description

NHS-SS-biotin is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

Uses

NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT.

Biological Activity

nhs-ss-biotin (succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 a in length due to the existence of a cross-bridge within its chemical structure. the long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. the nhs ester group of nhs-ss-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-nhs. nhs-ss-biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-SS-NHS ester 122266-55-1
Price
US $0.00/mg
Min. Order
50mg
Purity
>95.00%
Supply Ability
50mg
Release date
2024-03-21

122266-55-1, BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLERelated Search:


  • SULFOBIOTIN-X-NHS, CLEAVABLE
  • SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE
  • SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE
  • SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE
  • NHS-SS-BIOTIN
  • BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
  • Sulfo-SS-Biotin
  • NHS-SS-biotin,Biotin-SS-NHS
  • Biotin-SS-NHS ester
  • Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 122266-55-1
  • C19H28N4O6S3
  • Biotinylation Reagents