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IDOXIFENE

Product Name
IDOXIFENE
CAS No.
116057-75-1
Chemical Name
IDOXIFENE
Synonyms
cb7432;DOXIFENE;SB 223030;IDOXIFENE;iodoxifene;(e)-pyrrolidin;Idoxifene (CB7432);IDOXIFENE USP/EP/BP;pyrrolidino-4-iodotamoxifen;(e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
CBNumber
CB4227788
Molecular Formula
C28H30INO
Formula Weight
523.45
MOL File
116057-75-1.mol
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IDOXIFENE Property

Melting point:
108-109° (McCague et al.)
Boiling point:
573.4±50.0 °C(Predicted)
Density 
1.329
storage temp. 
2-8°C
pka
9.61±0.20(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H303May be harmfulif swallowed

H350May cause cancer

H360May damage fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
I654050
Product name
Idoxifene
Packaging
5mg
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002974
Product name
IDOXIFENE
Purity
95.00%
Packaging
5MG
Price
$502.76
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
46854
Product name
Idoxifene
Packaging
5mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002974
Product name
IDOXIFENE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
Alichem
Product number
116057751
Product name
(E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
Packaging
1g
Price
$690.8
Updated
2021/12/16
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IDOXIFENE Chemical Properties,Usage,Production

Uses

SERM for treatment of urogenital atrophy weak estrogen and antiestrogen in uterus

Uses

Idoxifene is a non-steroidal estrogen antagonist. It is structurally analogous to tamoxifen (T006000).

Definition

ChEBI: Idoxifene is a stilbenoid.

in vivo

Animals receive daily intraperitoneal injections of Estradiol (0.5 mg/kg) and an oral gavage of Idoxifene (0.02, 0.1, and 0.5 mg/kg) for 3 days after Dimethylnitrosamine (DMN) treatment. The blood levels of LDH and Estradiol (E2) and histological grades (scores 0 to 5) of liver zone 3 necrosis are evaluated. Idoxifene at doses of over 0.1 mg/kg significantly reduces the hepatic levels of collagen and MDA in the DMN model in a dose-dependent manner. Although Idoxifene and E2 are administered by different routes, i.e., by oral ingestion and intraperitoneal injection, respectively, the antifibrotic effect of a dose of 0.5 mg/kg of Idoxifene is somewhat greater than that of the same dose of E2[2].

IDOXIFENE Preparation Products And Raw materials

Raw materials

Preparation Products

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IDOXIFENE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Qingdao Kingway Pharmtech Co., Ltd.
Tel
0532-87118899
Fax
0532-84117788
Email
sales@kingwaypharm.com
Country
China
ProdList
119
Advantage
56
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 17714375163
Email
yftan@aikonchem.com
Country
China
ProdList
16676
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4817
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
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View Lastest Price from IDOXIFENE manufacturers

Dideu Industries Group Limited
Product
IDOXIFENE 116057-75-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-30
Shaanxi Dideu Medichem Co. Ltd
Product
Idoxifene 116057-75-1
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
800 tons
Release date
2020-04-29

116057-75-1, IDOXIFENERelated Search:


  • IDOXIFENE
  • (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
  • (e)-pyrrolidin
  • cb7432
  • iodoxifene
  • pyrrolidino-4-iodotamoxifen
  • (E)-1-[4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene
  • 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]pyrrolidine
  • SB 223030
  • (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
  • Pyrrolidine, 1-[2-[4-[(1E)-1-(4-iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-
  • IDOXIFENE USP/EP/BP
  • DOXIFENE
  • Idoxifene (CB7432)
  • 116057-75-1
  • C28H30INO