IDOXIFENE
- Product Name
- IDOXIFENE
- CAS No.
- 116057-75-1
- Chemical Name
- IDOXIFENE
- Synonyms
- cb7432;DOXIFENE;SB 223030;IDOXIFENE;iodoxifene;(e)-pyrrolidin;Idoxifene (CB7432);IDOXIFENE USP/EP/BP;pyrrolidino-4-iodotamoxifen;(e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
- CBNumber
- CB4227788
- Molecular Formula
- C28H30INO
- Formula Weight
- 523.45
- MOL File
- 116057-75-1.mol
IDOXIFENE Property
- Melting point:
- 108-109° (McCague et al.)
- Boiling point:
- 573.4±50.0 °C(Predicted)
- Density
- 1.329
- storage temp.
- 2-8°C
- pka
- 9.61±0.20(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- I654050
- Product name
- Idoxifene
- Packaging
- 5mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- API0002974
- Product name
- IDOXIFENE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.76
- Updated
- 2021/12/16
- Product number
- 46854
- Product name
- Idoxifene
- Packaging
- 5mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- API0002974
- Product name
- IDOXIFENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1575
- Updated
- 2021/12/16
- Product number
- 116057751
- Product name
- (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
- Packaging
- 1g
- Price
- $690.8
- Updated
- 2021/12/16
IDOXIFENE Chemical Properties,Usage,Production
Uses
SERM for treatment of urogenital atrophy weak estrogen and antiestrogen in uterus
Uses
Idoxifene is a non-steroidal estrogen antagonist. It is structurally analogous to tamoxifen (T006000).
Definition
ChEBI: Idoxifene is a stilbenoid.
in vivo
Animals receive daily intraperitoneal injections of Estradiol (0.5 mg/kg) and an oral gavage of Idoxifene (0.02, 0.1, and 0.5 mg/kg) for 3 days after Dimethylnitrosamine (DMN) treatment. The blood levels of LDH and Estradiol (E2) and histological grades (scores 0 to 5) of liver zone 3 necrosis are evaluated. Idoxifene at doses of over 0.1 mg/kg significantly reduces the hepatic levels of collagen and MDA in the DMN model in a dose-dependent manner. Although Idoxifene and E2 are administered by different routes, i.e., by oral ingestion and intraperitoneal injection, respectively, the antifibrotic effect of a dose of 0.5 mg/kg of Idoxifene is somewhat greater than that of the same dose of E2[2].
IDOXIFENE Preparation Products And Raw materials
Raw materials
Preparation Products
IDOXIFENE Suppliers
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View Lastest Price from IDOXIFENE manufacturers
- Product
- IDOXIFENE 116057-75-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-30
- Product
- Idoxifene 116057-75-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 800 tons
- Release date
- 2020-04-29