ChemicalBook > CAS DataBase List > IDOXIFENE

IDOXIFENE

Product Name
IDOXIFENE
CAS No.
116057-75-1
Chemical Name
IDOXIFENE
Synonyms
cb7432;DOXIFENE;SB 223030;IDOXIFENE;iodoxifene;(e)-pyrrolidin;Idoxifene (CB7432);IDOXIFENE USP/EP/BP;pyrrolidino-4-iodotamoxifen;(e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
CBNumber
CB4227788
Molecular Formula
C28H30INO
Formula Weight
523.45
MOL File
116057-75-1.mol
More
Less

IDOXIFENE Property

Melting point:
108-109° (McCague et al.)
Boiling point:
573.4±50.0 °C(Predicted)
Density 
1.329
storage temp. 
2-8°C
pka
9.61±0.20(Predicted)
form 
Solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
I654050
Product name
Idoxifene
Packaging
5mg
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002974
Product name
IDOXIFENE
Purity
95.00%
Packaging
5MG
Price
$502.76
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
46854
Product name
Idoxifene
Packaging
5mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002974
Product name
IDOXIFENE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
Alichem
Product number
116057751
Product name
(E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
Packaging
1g
Price
$690.8
Updated
2021/12/16
More
Less

IDOXIFENE Chemical Properties,Usage,Production

Uses

SERM for treatment of urogenital atrophy weak estrogen and antiestrogen in uterus

Uses

Idoxifene is a non-steroidal estrogen antagonist. It is structurally analogous to tamoxifen (T006000).

Definition

ChEBI: Idoxifene is a stilbenoid.

in vivo

Animals receive daily intraperitoneal injections of Estradiol (0.5 mg/kg) and an oral gavage of Idoxifene (0.02, 0.1, and 0.5 mg/kg) for 3 days after Dimethylnitrosamine (DMN) treatment. The blood levels of LDH and Estradiol (E2) and histological grades (scores 0 to 5) of liver zone 3 necrosis are evaluated. Idoxifene at doses of over 0.1 mg/kg significantly reduces the hepatic levels of collagen and MDA in the DMN model in a dose-dependent manner. Although Idoxifene and E2 are administered by different routes, i.e., by oral ingestion and intraperitoneal injection, respectively, the antifibrotic effect of a dose of 0.5 mg/kg of Idoxifene is somewhat greater than that of the same dose of E2[2].

IDOXIFENE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

IDOXIFENE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Qingdao Kingway Pharmtech Co., Ltd.
Tel
0532-87118899
Fax
0532-84117788
Email
sales@kingwaypharm.com
Country
China
ProdList
119
Advantage
56
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2989
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
More
Less

View Lastest Price from IDOXIFENE manufacturers

Dideu Industries Group Limited
Product
IDOXIFENE 116057-75-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-30
Shaanxi Dideu Medichem Co. Ltd
Product
Idoxifene 116057-75-1
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
800 tons
Release date
2020-04-29

116057-75-1, IDOXIFENERelated Search:


  • IDOXIFENE
  • (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
  • (e)-pyrrolidin
  • cb7432
  • iodoxifene
  • pyrrolidino-4-iodotamoxifen
  • (E)-1-[4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene
  • 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]pyrrolidine
  • SB 223030
  • (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
  • Pyrrolidine, 1-[2-[4-[(1E)-1-(4-iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-
  • IDOXIFENE USP/EP/BP
  • DOXIFENE
  • Idoxifene (CB7432)
  • 116057-75-1
  • C28H30INO