IDOXIFENE

Product Name: IDOXIFENE
CAS No.: 116057-75-1
Chemical Name: IDOXIFENE
Synonyms: cb7432;DOXIFENE;SB 223030;IDOXIFENE;iodoxifene;(e)-pyrrolidin;Idoxifene (CB7432);IDOXIFENE USP/EP/BP;pyrrolidino-4-iodotamoxifen;(e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine
CBNumber: CB4227788
Molecular Formula: C28H30INO
Formula Weight: 523.45
MOL File: 116057-75-1.mol

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IDOXIFENE Property

Melting point:: 108-109° (McCague et al.)
Boiling point:: 573.4±50.0 °C(Predicted)
Density: 1.329
storage temp.: 2-8°C
pka: 9.61±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: I654050
Product name: Idoxifene
Packaging: 5mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002974
Product name: IDOXIFENE
Purity: 95.00%
Packaging: 5MG
Price: $502.76
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 46854
Product name: Idoxifene
Packaging: 5mg
Price: $650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002974
Product name: IDOXIFENE
Purity: 95.00%
Packaging: 1G
Price: $1575
Updated: 2021/12/16

Alichem

Product number: 116057751
Product name: (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine
Packaging: 1g
Price: $690.8
Updated: 2021/12/16

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IDOXIFENE Chemical Properties,Usage,Production

Uses

SERM for treatment of urogenital atrophy weak estrogen and antiestrogen in uterus

Uses

Idoxifene is a non-steroidal estrogen antagonist. It is structurally analogous to tamoxifen (T006000).

Definition

ChEBI: Idoxifene is a stilbenoid.

in vivo

Animals receive daily intraperitoneal injections of Estradiol (0.5 mg/kg) and an oral gavage of Idoxifene (0.02, 0.1, and 0.5 mg/kg) for 3 days after Dimethylnitrosamine (DMN) treatment. The blood levels of LDH and Estradiol (E2) and histological grades (scores 0 to 5) of liver zone 3 necrosis are evaluated. Idoxifene at doses of over 0.1 mg/kg significantly reduces the hepatic levels of collagen and MDA in the DMN model in a dose-dependent manner. Although Idoxifene and E2 are administered by different routes, i.e., by oral ingestion and intraperitoneal injection, respectively, the antifibrotic effect of a dose of 0.5 mg/kg of Idoxifene is somewhat greater than that of the same dose of E2^[2].

IDOXIFENE Preparation Products And Raw materials

Raw materials

Preparation Products

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IDOXIFENE Suppliers

China 31 Europe 2 India 1 United Kingdom 6 United States 15 Global 55

J & K SCIENTIFIC LTD.

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View Lastest Price from IDOXIFENE manufacturers

Dideu Industries Group Limited

Product: IDOXIFENE 116057-75-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-30

Shaanxi Dideu Medichem Co. Ltd

Product: Idoxifene 116057-75-1
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

116057-75-1, IDOXIFENERelated Search:

Buflomedil hydrochloride Acrivastine Cyclophosphamide monohydrate Propafenone Raloxifene Bazedoxifene 4-IODODIPHENYLMETHANE desdimethyltamoxifen Tamoxifen Tesmilifene 4-iodotamoxifen IDOXIFENE

IDOXIFENE

(e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine

(e)-pyrrolidin

cb7432

iodoxifene

pyrrolidino-4-iodotamoxifen

(E)-1-[4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene

1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]pyrrolidine

SB 223030

(E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine

Pyrrolidine, 1-[2-[4-[(1E)-1-(4-iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-

IDOXIFENE USP/EP/BP

DOXIFENE

Idoxifene (CB7432)

116057-75-1

C28H30INO