Benserazide hydrochloride
- Product Name
- Benserazide hydrochloride
- CAS No.
- 14919-77-8
- Chemical Name
- Benserazide hydrochloride
- Synonyms
- BENSERAZIDE HCL;RO 4-4602;BENPARIZDE;31796-68-6;Ro 4-4602/001;NCGC00093698-03;SPECTRUM1500137;Benserazide hydrochlo;Benserazid hydrochloride;BENSERAZIDE HYDROCHLORIDE
- CBNumber
- CB4229025
- Molecular Formula
- C10H16ClN3O5
- Formula Weight
- 293.7
- MOL File
- 14919-77-8.mol
Benserazide hydrochloride Property
- Melting point:
- 146°C
- storage temp.
- 2-8°C
- solubility
- H2O: 10 mg/mL
- form
- solid
- color
- White to Off-White
- PH
- pH(10g/L, 25℃) : 4.0～5.0
- Water Solubility
- Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone.
- Sensitive
- Light Sensitive
- λmax
- 272nm(HCl aq.)(lit.)
- Merck
- 14,1050
- InChIKey
- ULFCBIUXQQYDEI-UHFFFAOYSA-N
- CAS DataBase Reference
- 14919-77-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Y0002115
- Product name
- Benserazide for peak identification A
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- Y0002115
- Price
- $150
- Updated
- 2024/03/01
- Product number
- B7283
- Product name
- Benserazide hydrochloride
- Purity
- ≥98% (TLC), solid
- Packaging
- 1g
- Price
- $120
- Updated
- 2024/03/01
- Product number
- BP685
- Product name
- Benserazide hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $275
- Updated
- 2024/03/01
- Product number
- B7283
- Product name
- Benserazide hydrochloride
- Purity
- ≥98% (TLC), solid
- Packaging
- 5g
- Price
- $417
- Updated
- 2024/03/01
- Product number
- B4108
- Product name
- Benserazide Hydrochloride
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $65
- Updated
- 2024/03/01
Benserazide hydrochloride Chemical Properties,Usage,Production
Description
Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.
Chemical Properties
White Crystalline Solid
Uses
Used as antiparkinsonian. A peripheral decarboxylase inhibitor
Uses
Antiparkinsonian;DOPA decarboxylase inhibitor
Uses
Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.
Definition
ChEBI: A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of park nsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions whe given alone.
General Description
Benserazide is a peripheral decarboxylase inhibitor.
Biochem/physiol Actions
Inhibitor of L-aromatic amino acid decarboxylase.
Benserazide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Benserazide hydrochloride Suppliers
- Tel
- --
- Fax
- --
- guedj.gregory@kleos-pharma.com
- Country
- France
- ProdList
- 298
- Advantage
- 58
- Tel
- --
- Fax
- --
- orders@edqm.eu
- Country
- France
- ProdList
- 1913
- Advantage
- 81
View Lastest Price from Benserazide hydrochloride manufacturers
- Product
- Benserazide hydrochloride 14919-77-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.5%~101.0%,EP
- Supply Ability
- 800kg/month
- Release date
- 2021-06-18
- Product
- Benserazide hydrochloride 14919-77-8
- Price
- US $0.00/KG
- Min. Order
- 100g
- Purity
- 98%+
- Supply Ability
- 100kg
- Release date
- 2020-11-16
- Product
- Benserazide Hydrochloride 14919-77-8
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-12-22