ChemicalBook > CAS DataBase List > Nimustine
Nimustine
- Product Name
- Nimustine
- CAS No.
- 42471-28-3
- Chemical Name
- Nimustine
- Synonyms
- ACNU;ACNU 50;Nimustin;NIMUSTINE;NITROSOUREA;NIFUMICACID;NIMUSTINE HCL;Nimustine USP/EP/BP;pimustine hydrochloride;1,2-DibroMo-3-chloropropane Standard
- CBNumber
- CB4231103
- Molecular Formula
- C9H13ClN6O2
- Formula Weight
- 272.69
- MOL File
- 42471-28-3.mol
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Nimustine Property
- Melting point:
- 125°C (rough estimate)
- Boiling point:
- 98°C (rough estimate)
- Density
- 1.9048 (rough estimate)
- refractive index
- 1.5790 (estimate)
- pka
- 9.58±0.46(Predicted)
- form
- solid
- CAS DataBase Reference
- 42471-28-3(CAS DataBase Reference)
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Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- YR8450000
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0003580
- Product name
- NIMUSTINE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $402.7
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0003580
- Product name
- NIMUSTINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $427.5
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0003580
- Product name
- NIMUSTINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $537.5
- Updated
- 2021/12/16
AHH
- Product number
- API-1243
- Product name
- Nimustine
- Purity
- 98%
- Packaging
- 10g
- Price
- $320
- Updated
- 2021/12/16
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Nimustine Chemical Properties,Usage,Production
Originator
Nidran,Sankyo,Japan,1979
Definition
ChEBI: An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An anti eoplastic agent especially effective against malignant brain tumors.
Manufacturing Process
0.4 g of sodium nitrite was added with stirring, at 0°C to 5°C, to a solution of
450 mg of 1-(2-chloroethyl)-3-[(2-methyl-4-aminopyridin-5-yl)methyl]urea in
8 ml of 5% hydrochloric acid, and the reaction mixture was then stirred at
0°C to 10°C for an additional 1.5 hours.
After completion of the reaction, the reaction mixture was made alkaline by
the addition of sodium carbonate, whereupon crystals separated out in situ.
The crystals were recovered by filtration, washed with water and then
recrystallized from 6 ml of ethanol, to give 0.1 g of the pale yellow pure
desired product having a decomposition point of 125°C.
Therapeutic Function
Antitumor, Antileukemic
Nimustine Preparation Products And Raw materials
Raw materials
Preparation Products
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Nimustine Suppliers
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- 1-(800)-881-8210
- Fax
- 615-250-9817
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View Lastest Price from Nimustine manufacturers
Dideu Industries Group Limited
- Product
- Nimustine 42471-28-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-05
Career Henan Chemical Co
- Product
- Nimustine 42471-28-3
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-01-08
42471-28-3, NimustineRelated Search:
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NIMUSTINE HYDROCHLORIDE,NIMUSTINE HCL
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