ChemicalBook > CAS DataBase List > CORTISOL-9,11,12,12-D4

CORTISOL-9,11,12,12-D4

Product Name
CORTISOL-9,11,12,12-D4
CAS No.
73565-87-4
Chemical Name
CORTISOL-9,11,12,12-D4
Synonyms
Hycort-d4;Acticort-d4;Hycortol-d4;Texacort-d4;TiMocort-d4;Cortisol-d4;DerMacort-d4;Hydrocortal-d4;[2H4]-Cortisol;Deuterated cortisol
CBNumber
CB4234270
Molecular Formula
C21H26D4O5
Formula Weight
366.49
MOL File
73565-87-4.mol
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CORTISOL-9,11,12,12-D4 Property

Melting point:
211-214 °C
Flash point:
9℃
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Heated), Water
form 
Solid
color 
White to Off-White
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
63-39/23/24/25-23/24/25-11
Safety Statements 
36/37-45-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C-113
Product name
Cortisol-D4 (9,11,12, 12-D4) solution
Purity
100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$474
Updated
2024/03/01
Sigma-Aldrich
Product number
705594
Product name
Hydrocortisone-9,11,12,12-d4
Purity
98 atom % D, 98% (CP)
Packaging
5mg
Price
$921
Updated
2024/03/01
Sigma-Aldrich
Product number
705594
Product name
Hydrocortisone-9,11,12,12-d4
Purity
98 atom % D, 98% (CP)
Packaging
10mg
Price
$1610
Updated
2024/03/01
Cayman Chemical
Product number
26500
Product name
Hydrocortisone-d4
Packaging
500μg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
26500
Product name
Hydrocortisone-d4
Packaging
5mg
Price
$684
Updated
2024/03/01
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CORTISOL-9,11,12,12-D4 Chemical Properties,Usage,Production

Description

Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.

Chemical Properties

White Solid

Uses

Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Uses

Anti-inflammatory hormone

General Description

Cortisol, also known as hydrocortisone, is a glucocorticoid produced by the adrenal gland. This stable labeled internal standard is suitable for quantitation of cortisol levels in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, Addison′s disease, and Sheehan′s syndrome.

CORTISOL-9,11,12,12-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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CORTISOL-9,11,12,12-D4 Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
Advantage
58
SIMSON PHARMA LIMITED
Tel
+91-8291074273
Email
k.das@simsonpharma.com
Country
India
ProdList
228
Advantage
58

73565-87-4, CORTISOL-9,11,12,12-D4Related Search:


  • 17-Hydroxycorticosterone-9,11,12,12-d4, Cortisol-9,11,12,12-d4, Hydrocortisone-9,11,12,12-d4, Kendall's compound F (9,11,12,12-d4), Reichstein's substance M (9,11,12,12-d4), 4-Pregnene-11β,17α,21-triol-3,20-dione-d4 (9,11,12,12-d4), 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4)
  • CORTISOL-9,11,12,12-D4
  • HYDROCORTISONE (9,11,12,12-D4)
  • Cortisol-D4 (9,11,12,12-D4)
  • (11β)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione-d4
  • 11β-Hydroxycortisone-d4
  • 17-Hydroxycorticosterone-d4
  • Acticort-d4
  • (8S,10R,11S,13S)-9,11,12,12-tetradeuterio-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • DerMacort-d4
  • Hycort-d4
  • Hycortol-d4
  • Hydrocortal-d4
  • Pregn-4-ene-3,20-dione-d4
  • Texacort-d4
  • TiMocort-d4
  • Cortisol-d4
  • 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4
  • Cortisol-[D4] (CertiMass solution)
  • Cortisol-D4 (9,11,12, 12-D4) solution
  • Cortisol-D4 (9,11,12,12-D4) solution
  • Hydrocortisone-9,11,12,12-D4 solution
  • Deuterated cortisol
  • Deuterated hydrocortisone
  • Pregn-4-ene-3,20-dione-9,11,12,12-d4,11,17,21-trihydroxy-, (11b)-
  • 4-Pregnene-11β,17α,21-triol-3,20-dione-D4
  • Cortisol-[d4] (Solution)
  • [2H4]-Cortisol
  • Hydrocortisone D4Q: What is Hydrocortisone D4 Q: What is the CAS Number of Hydrocortisone D4 Q: What is the storage condition of Hydrocortisone D4 Q: What are the applications of Hydrocortisone D4
  • Hydrocortisone-d4 (Cortisol-d4)
  • Pregn-4-ene-3,20-dione-9,11,12,12-d4, 11,17,21-trihydroxy-, (11β)-
  • Cortisol-9,11,12,12-d?
  • 73565-87-4
  • C21H26D4O5
  • C21D4H26O5
  • C21H26D4O4
  • Steroids & Hormones - 13C & 2H
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Steroids